Results 71 to 80 of about 19,003 (253)

Effectiveness of Sugammadex on muscle relaxant reversal in preterm neonates

Egyptian Journal of Anaesthesia, 2023
Background & objective Sugammadex is a drug used to reverse the muscle relaxation effect of rocuronium. Its use is still limited in preterm neonates. The aim of this study was to compare the efficacy of Sugammadex with that of neostigmine in reversing ...
Ahmed Mohamed Ahmed Elshafie, Ahmed Ezzat Marzouq Sad Elrouby, Yasser Mohamed Osman   +2 more
doaj   +1 more source

Hippocampal‐Specific Insulin Resistance Elicits Synaptic Effects on Glutamate Neurotransmission

Journal of Neurochemistry, Volume 169, Issue 6, June 2025.
In animals with hippocampal‐specific insulin resistance, reduced vGluT2 and synaptophysin expression resulted in lowered synaptic glutamate concentrations. These animals also exhibited reduced serine phosphorylation of GluA1 (green postsynaptic receptor) and reduced expression of GluN2B (purple postsynaptic receptor).
Jennifer M. Erichsen, Jennifer L. Woodruff, Claudia A. Grillo, Gerardo G. Piroli, Jim R. Fadel, Lawrence P. Reagan   +5 more
wiley   +1 more source

Evaluation of the Alterations in Central Cholinergic Neurotransmission in Aging and Amyloid Precursor Protein Knock‐In Mice

Journal of Neurochemistry, Volume 169, Issue 5, May 2025.
In Alzheimer's disease, reduced release of ACh is linked more to Aβ pathology than to age‐related change, highlighting an early sign of disease. ABSTRACT A progressive decline in cognitive function occurs as a result of aging and Alzheimer's disease (AD) and is primarily associated with diminished cholinergic neurotransmission.
Itsumi Nagai‐Arakawa, Ikunobu Muramatsu, Junsuke Uwada, Yo Tsuda, Akinori Tokunaga, Ai Irie, Hideyuki Maeda, Yuta Madokoro, Toyohiro Sato, Yuto Uchida, Takashi Saito, Takaomi C. Saido, Kiyonao Sada, Takayoshi Masuoka, Noriyuki Matsukawa   +14 more
wiley   +1 more source

Reversal of profound vecuronium-induced neuromuscular block under sevoflurane anesthesia: sugammadex versus neostigmine.

BMC Anesthesiology, 2010
Background Acetylcholinesterase inhibitors cannot rapidly reverse profound neuromuscular block. Sugammadex, a selective relaxant binding agent, reverses the effects of rocuronium and vecuronium by encapsulation.
Lemmens Hendrikus JM, El-Orbany Mohammad I, Berry James, Morte Jovino, Martin Gavin   +4 more
doaj   +1 more source

Neostigmine and atropine as a treatment for postdural puncture headache after spinal anesthesia in cesarean section: A case report

Clinical Case Reports, 2023
Key Clinical message Neostigmine and atropine offer a promising treatment option for postdural puncture headache (PDPH) following spinal anesthesia in cesarean section, providing effective relief with a favorable risk–benefit profile.
Indra Kumar Shrestha, Rupak Chalise, Saroj Poudel, Ashim Regmi, Anup Ghimire, Bikash Khadka, Kishor Khanal   +6 more
doaj   +1 more source

Perioperative analgesic effects of a modified supratemporal retrobulbar block in dogs undergoing corneal and endocular surgery

Journal of Small Animal Practice, Volume 66, Issue 5, Page 328-334, May 2025.
Objectives To evaluate the perioperative efficacy of a modified supratemporal retrobulbar block in dogs undergoing ocular surgery. Materials and Methods In this prospective randomised clinical trial, dogs were premedicated with dexmedetomidine (1 mcg/kg im) and methadone (0.1 mg/kg im), induced with propofol to effect and maintained with isoflurane (FE'
E. Lardone, M. Crasta, P. C. Ostan, P. Gherlinzoni, A. Landi, P. Franci   +5 more
wiley   +1 more source

Sugammadex for reversal of neuromuscular blockade: a retrospective analysis of clinical outcomes and cost-effectiveness in a single center

ClinicoEconomics and Outcomes Research, 2016
Michele Carron, Fabio Baratto, Francesco Zarantonello, Carlo Ori Department of Medicine, Anesthesiology and Intensive Care, University of Padova, Padova, Italy Objective: The aim of the study is to evaluate the clinical and economic impact of introducing
Carron M, Baratto F, Zarantonello F, Ori C   +3 more
doaj  

Neostigmine treatment protocols applied in acute colonic pseudo-obstruction disease: A retrospective comparative study.

The Turkish Journal of Gastroenterology, 2019
BACKGROUND/AIMS When conservative methods fail, neostigmine is recommended in the pharmacological treatment of acute colonic pseudo-obstruction (ACPO). The objective of this study was to analyze the response of patients to different neostigmine protocols.
Ömür İlban, F. Çiçekçi, J. Celik, M. Baş, A. Duman   +4 more
semanticscholar   +1 more source

Case Series of Canine Myasthenia Gravis: A Classification Approach With Consideration of Seronegative Dogs

Journal of Veterinary Internal Medicine, Volume 39, Issue 3, May/June 2025.
ABSTRACT Background Myasthenia gravis (MG) is categorized into several subgroups, including seronegative MG. Seronegative human patients are well documented, but seronegative dogs remain clinically uncharacterized and their prevalence unknown. Objectives This study aims to evaluate the clinical presentation, diagnosis, treatment, and outcome of canine ...
Rui Xavier Dos Santos, Jan Waelkens, Abbe H. Crawford, Sam Khan, Sara Sami, Sergio A. Gomes, Anouk Van Ham, Iris Van Soens, Ine Cornelis, Jake Canning, Joe Fenn, Patrick Waters, Sofie F. M. Bhatti, An E. Vanhaesebrouck   +13 more
wiley   +1 more source

Dermal reaction and bigeminal premature ventricular contractions due to neostigmine: a case report

Journal of Medical Case Reports, 2011
Introduction Neostigmine is a frequently used acetylcholinesterase inhibitor administered to reverse muscular relaxation caused by nondepolarizing neuromuscular relaxants in patients recovering from general anesthesia.
Khashayar Patricia, Anbarafshan Mohammad, Yousefshahi Fardin   +2 more
doaj   +1 more source