Results 101 to 110 of about 36,146 (282)

Irigenin Modulates BL‐Induced Pyroptosis in Retinal Pigment Epithelial Cells Through p38 MAPK and NFκB Pathways

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 2, February 2026.
Irigenin alleviates blue light‐induced RPE cell damage by inhibiting NLRP3 inflammasome and p38/NF‐κB signalling, showing potential for AMD prevention. ABSTRACT Age‐related macular degeneration (AMD), a primary cause of vision loss among older adults, is strongly associated with inflammatory processes.
I‐Li Su, Kun‐Lin Yeh, Chien‐Ying Lee, Sheng‐Chien Lin, Chen‐Yu Chiang, Chun‐Jung Chen, Wen‐Ying Chen, Ching‐Chi Tseng, Yin‐Che Lu, Yu‐Hsiang Kuan   +9 more
wiley   +1 more source

Functional Outcomes of the Low Vision Depression Prevention Trial in Age-Related Macular Degeneration. [PDF]

, 2017
Purpose: To compare the efficacy of behavioral activation (BA) plus low vision rehabilitation with an occupational therapist (OT-LVR) with supportive therapy (ST) on visual function in patients with age-related macular degeneration (AMD). Methods: Single-
Casten, Robin J., Deemer, Ashley D., Massof, Robert W., Piersol, Catherine V., Rovner, Barry W.   +4 more
core   +3 more sources

Progress in RNA‐Targeted Therapeutics for Human Diseases

MedComm, Volume 7, Issue 2, February 2026.
RNA‐targeted therapies are revolutionizing molecular medicine by transitioning from a “protein‐centric” focus to an “RNA‐regulatory network” approach. Leveraging RNA's diverse roles in gene regulation, signaling, and epigenetic modifications, advanced platforms such as ASOs, siRNA, miRNA, mRNA, aptamers, shRNA, and CRISPR/Cas systems are enabling ...
Wangzheqi Zhang, Aimin Jiang, Bin‐Kui Jia, Yuming Jin, Yinghu Chen, Zhaoyu Li, Yan Liao, Haoling Zhang, Zhiheng Lin, Xiao Fang, Linhui Wang   +10 more
wiley   +1 more source

'You've got dry macular degeneration, end of story': a qualitative study into the experience of living with non-neovascular age-related macular degeneration. [PDF]

, 2019
BACKGROUND/OBJECTIVES: To investigate the impact of non-neovascular (dry) age-related macular degeneration (AMD) on the person with respect to diagnosis, vision loss and coping strategies.
Binns, A. M., Crabb, D. P., Jones, L., Taylor, D. J.   +3 more
core   +2 more sources

MSC‐Derived Exosomal lnc‐AGT‐3: A Novel Anti‐Angiogenic Target in Age‐Related Macular Degeneration Through p53 Signaling Pathway

Aging Cell, Volume 25, Issue 2, February 2026.
MSC‐derived exosomes deliver lnc‐AGT‐3 to vascular endothelial cells, where it binds hnRNP K in the nucleus. This interaction inhibits p53 ubiquitination, enhancing p53 stabilization and transcriptional activation of anti‐angiogenic targets TSP1. Consequently, p53‐mediated signaling is potentiated, effectively suppressing choroidal neovascularization ...
Lingjie Kong, Xiaoyan Han, Siyi Qi, Duo Li, Jingyue Zhang, Linyu Zhang, Shujie Zhang, Qin Jiang, Biao Yan, Chen Zhao   +9 more
wiley   +1 more source

Real World Data Comparison of Standard Care vs SDM Laser Vision Protection Therapy for Prevention of Neovascular AMD

Clinical Ophthalmology, 2022
Jeffrey K Luttrull,1 Gerry Gray2 1Ventura County Retina Vitreous Medical Group, Ventura, CA, USA; 2Regulatory Pathways, Inc, Laguna Beach, CA, USACorrespondence: Jeffrey K Luttrull, Ventura County Retina Vitreous Medical Group, 3160 Telegraph Road, Suite
Luttrull JK, Gray G
doaj  

Intravitreal injections: A brief note

Kerala Journal of Ophthalmology, 2018
The delivery of medications directly into the vitreous cavity through an injection or implant has become a commonplace in ophthalmology. Common diseases treated by intravitreal injections include neovascular age-related macular degeneration, clinically ...
Anu Joseph
doaj   +1 more source

Intravitreal anti‐vascular endothelial growth factor injections and risks of stroke in patients with neovascular age‐related macular degeneration—A registry‐based cohort study

Acta Ophthalmologica, Volume 104, Issue 1, Page 98-105, February 2026.
Abstract Background Intravitreal Anti‐Vascular Endothelial Growth Factor (VEGF) rescues retinal vasculatures and prevents disease progression in patients with neovascular Age‐Related Macular Degeneration (nAMD). However, systemic anti‐VEGF may increase the risk of thromboembolic related complications including stroke and TIA. This study aims to explore
A. H. Falemban, K. Söderberg‐Löfdal, F. Jonsson, S. Almlöf‐Sarman, M. von Euler, I. Westborg   +5 more
wiley   +1 more source

Neovascular Age-related Macular Degeneration

, 2022
This thesis describes the treatment of exudative Age-Related Macular Degeneration (ARMD) with bevacizumab. The main object of the thesis was to evaluate the viability of less frequent bevacizumab dosage regiments. Furthermore, the reactivation interval of CNV was observed, and we delved deeper into a specific kind of CNV and its characteristics using a
openaire   +1 more source

Continuity of care and risk of vision loss in patients with newly developed macular degeneration

Acta Ophthalmologica, Volume 104, Issue 1, Page e39-e47, February 2026.
Abstract Purpose Neovascular age‐related macular degeneration (AMD) is a major cause of vision loss. Effective treatment requires sustained care, which may be influenced by continuity of care (COC). Understanding this association is crucial for improving patient outcomes.
In Hwan Cho, Minah Park, Dae Joong Ma, In Hwan Hong, Hyunkyu Kim, Seung Hoon Kim   +5 more
wiley   +1 more source