Results 71 to 80 of about 13,840,459 (217)

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source

Evaluation of the Safety and Therapeutic Range of Nanosecond Laser Treatment in Rabbits

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Subthreshold, nanosecond laser therapy has potential as a treatment for age‐related macular degeneration; however, the therapeutic range and safety profile have not been fully documented. In this study, rabbits were used for a preclinical assessment of nanosecond laser treatment.
Glyn Chidlow, John P. M. Wood, Weng Onn Chan, Robert J. Casson   +3 more
wiley   +1 more source

Ranibizumab in neovascular age-related macular degeneration: a 5-year follow-up [PDF]

, 2016
Nadezhda P Cvetkova, Kristina Hölldobler, Philipp Prahs, Viola Radeck, Horst Helbig, David Märker Department of Ophthalmology, University of Regensburg, Regensburg, Germany Purpose: Our aim was to evaluate an optical coherence tomography (OCT)
Hölldobler K, Radeck V, Helbig H, Märker D, Radeck, Viola, Cvetkova, Nadezhda, Prahs P, Märker, David, Prahs, Philipp, Cvetkova NP, Helbig, Horst, Hölldobler, Kristina   +11 more
core   +1 more source

Spotlight on Faricimab in the Treatment of Wet Age-Related Macular Degeneration: Design, Development and Place in Therapy

Drug Design, Development and Therapy, 2022
Archana A Nair, Avni P Finn, Paul Sternberg Jr Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, TN, USACorrespondence: Paul Sternberg Jr, Chair and G. W.
Nair AA, Finn AP, Sternberg P Jr
doaj  

The optical coherence tomography and microperimetry biomarker evaluation in patients with geographic atrophy (OMEGA) study: Geographic atrophy progression in fundus autofluorescence ‐ OMEGA report 3

Acta Ophthalmologica, Volume 104, Issue 7, Page 750-759, November 2026.
Abstract Purpose To measure the progression of geographic atrophy (GA) in subjects with age‐related macular degeneration (AMD) in a natural history study. Methods We analysed fundus autofluorescence (FAF) images using a semiautomatic method (RegionFinder) to quantify the GA area in a monocentric study.
Philippe Valmaggia, Georg Ansari, Nadja Inglin, Nils Schärer, Hanna Zuche, Chrysoula Gabrani, Faady Yahya, Marco Cattaneo, Kristina Pfau, Andrea Giani, Marieh Esmaeelpour, Taffeta Chingning Yamaguchi, Christian Prünte, Hendrik P. N. Scholl, Nicolas Feltgen, Leopold Schmetterer, Maximilian Pfau, Peter M. Maloca   +17 more
wiley   +1 more source

Ocular Manifestations of Metabolic Syndrome: A Systemic Vascular Phenotype

Diabetes, Obesity and Metabolism, Volume 28, Issue 11, Page 9809-9818, November 2026.
ABSTRACT Context Metabolic syndrome (MetS) is defined by central obesity, insulin resistance, hypertension and dyslipidemia. MetS affects over one‐third of US adults. Beyond its cardiovascular burden, MetS has clinically relevant associations with ocular health and may contribute to a systemic vascular and neuro‐metabolic phenotype involving the retina,
Ron T. Varghese, Ansu A. John
wiley   +1 more source

Reliability of colour perimetry to assess macular pigment optical density in age-related macular degeneration [PDF]

, 2020
Producción CientíficaABSTRACT: BACKGROUND: The aim of this study was to determine the intra-session repeatability and inter-examiner reproducibility of the colour perimetry technique when assessing in vivo macular pigment optical density in age-related ...
Coco Martín, Rosa María, Plata Cordero, María, Pichel Mouzo, María Dolores, Fernández Martínez, Itziar, López Miguel, Alberto   +4 more
core   +1 more source

Patients' preferences in treatment for neovascular age-related macular degeneration in clinical routine [PDF]

, 2012
To assess the effect of ranibizumab treatment for neovascular age-related macular degeneration (nvAMD) on patients' preferences and vision-related quality of life (VRQoL) in a routine clinical ...
Neubauer, Aljoscha S., Hoffmann, Andrea E., Fenwick, Eva K., Finger, Robert P., Wolf, Armin, Hirneiss, Christoph, Kampik, Anselm, Kernt, Marcus, Finger, Robert   +8 more
core   +1 more source

Photodynamic therapy for neovascular age-related macular degeneration

Philippine Journal of Ophthalmology, 2005
Background: In neovascular age-related macular degeneration (ARMD) new vessels grow under the retina, distorting vision and leading to scarring. This is exacerbated if the blood vessels leak.
Richard P.L. Wormald, MA, MB, BCh, MSc, FRCS, FRCOphth, Jennifer R Evans, PhD, Katherine S Henshaw, Liam L Smeeth, MD   +3 more
doaj  

Cutting Edge Advancements in Management of Neovascular Age-Related Macular Degeneration A Scoping Review on Gene Therapy

IJRETINA (International Journal of Retina)
Introduction: Age-related macular degeneration (AMD) is the fourth leading cause of blindness globally. Therapeutic strategies for neovascular AMD (nAMD) have utilized anti-VEGF proteins, however compliance has become an issue. This study aims to explore
Diannisa Paramita Susantono, Andi Arus Victor   +1 more
doaj   +1 more source