Results 101 to 110 of about 14,897 (210)

Emerging techniques to treat corneal neovascularisation [PDF]

Eye, 2011
Neovascularisation is a major cause of visual loss in a number of ophthalmic diseases. This review aims to outline the basic regulators of vessel growth in corneal neovascularisation. An understanding of the underlying principles of physiological and pathophysiological vascular development helps to appreciate current approaches to prevent or treat ...
openaire   +2 more sources

Paediatric Choroidal Neovascularisation of Unknown Cause

Cureus
Choroidal neovascularisation (CNV) is a condition characterised by the proliferation of abnormal blood vessels within the choroid. These vessels tend to leak blood and fluid into the adjacent tissues, thereby causing harm to the retina and posing a threat to visual function.
Elghazali Bakhiet, Tasneem, Hassan, Shoaib, Shankar, Jai   +2 more
openaire   +2 more sources

Intimal neovascularisation is a prominent feature of atherosclerotic plaques in diabetic patients with critical limb ischaemia.

, 2016
INTRODUCTION: Neovascularisation of atherosclerotic plaques correlates with increased plaque instability and subsequent risk of vascular complications. Diabetics have widespread atherosclerotic involvement of the arterial tree and a more aggressive form ...

core   +1 more source

CAMKII as a therapeutic target for growth factor-induced retinal and choroidal neovascularisation [PDF]

, 2019
While anti-VEGF drugs are commonly used to inhibit pathological retinal and choroidal neovascularization, not all patients respond in an optimal manner.
Canning, Paul, Curtis, Tim M, Micu, Ileana, Fernandez, Jose A, Ashraf, Sadaf, Brazil, Derek P, McGeown, J Graham, Stitt, Alan W; id_orcid, McCauley, Hannah, O'Leary, Caitriona, O'Hare, Michael, Bell, Samuel, Stitt, Alan W, Barabas, Peter, O'Hare, Michael; id_orcid, Michael O'Hare, Peter Barabas, Alan W. Stitt, Hannah McCauley, Tim M. Curtis, Ileana Micu, Paul Canning, Sadaf Ashraf, Caitriona O'Leary, Samuel Bell, Derek P. Brazil, Jose A. Fernandez, J. Graham McGeown   +27 more
core   +1 more source

Anti Vascular Endothelial Growth Factor Agents in Corneal Neovascularization

Delhi Journal of Ophthalmology, 2011
Corneal neovascularisation is a potentially blinding condition, an established risk factor for rejection and results in loss of immune privilege. It may occur as a normal physiologic healing response to various stimuli or as an inappropriate local tissue
Srivatsa Sehra, Reetika
doaj   +1 more source

Lutein and zeaxanthin attenuates VEGF-induced neovascularisation in human retinal microvascular endothelial cells through a Nox4-dependent pathway

, 2020
Age-related macular degeneration (AMD) and proliferative diabetic retinopathy (DR) are two of the most common and severe causes of vision loss in the population.
Gianne Keegan (16662135), Shahina Pardhan (841338), Havovi Chichger (16654908)   +2 more
core   +2 more sources

Anti-VEGF Therapy and the Retina: An Update

Journal of Ophthalmology, 2015
Ocular angiogenesis and macular oedema are major causes of sight loss across the world. Aberrant neovascularisation, which may arise secondary to numerous disease processes, can result in reduced vision as a result of oedema, haemorrhage, and scarring ...
Vikas Tah, Harry O. Orlans, Jonathan Hyer, Edward Casswell, Nizar Din, Vishnu Sri Shanmuganathan, Louise Ramskold, Saruban Pasu   +7 more
doaj   +1 more source

Heterotypic macrophages/microglia differentially contribute to retinal ischaemia and neovascularisation [PDF]

Aims/hypothesisDiabetic retinopathy is characterised by neuroinflammation that drives neuronal and vascular degenerative pathology, which in many individuals can lead to retinal ischaemia and neovascularisation.
Little, Karis, Kaizu, Yoshihiro, Garweg, Justus G., Zandi, Souska, Shiraishi, Wataru, Wada, Iori, Yamasaki, Ryo, Uemura, Akiyoshi, Singh, Aditi, Shibata, Kensuke, Little, Karis; id_orcid, Ishibashi, Tatsuro, Sonoda, Koh-Hei, Nakao, Shintaro, Garweg, Justus G, Arima, Mitsuru, Go, Yasuhiro, Stitt, Alan W.; id_orcid, Stitt, Alan W, Yamaguchi, Muneo, Matoba, Tetsuya   +20 more
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Assessment of microvascular flow in human atherosclerotic carotid plaques using ultrasound localization microscopyResearch in context

EBioMedicine
Summary: Background: Neovascularisation of carotid plaques contributes to their vulnerability. Current imaging methods such as contrast-enhanced ultrasound (CEUS) usually lack the required spatial resolution and quantification capability for precise ...
Henri Leroy, Louise Z. Wang, Anatole Jimenez, Nassim Mohamedi, Clément Papadacci, Pierre Julia, Salma El Batti, Jean-Marc Alsac, Jonas Sitruk, Armelle Arnoux, Patrick Bruneval, Emmanuel Messas, Tristan Mirault, Guillaume Goudot, Mathieu Pernot   +14 more
doaj   +1 more source

Neovascularisation. [PDF]

British Journal of Ophthalmology, 1986
openaire   +2 more sources