Results 101 to 110 of about 34,072 (291)

Advanced Biomaterial Delivery of Hypoxia‐Conditioned Extracellular Vesicles (EVs) as a Therapeutic Platform for Traumatic Brain Injury

Advanced Science, EarlyView.
This research introduces a novel approach to enhance neuroregeneration following Traumatic Brain Injury (TBI). Extracellular Vesicles (EVs) are isolated from human neural progenitor cells under hypoxic conditions, leading to enhanced expression of neurogenic and angiogenic factors.
Joshua B. Stein, Songzi Zhang, Eun Ji Roh, Jeffrey Luo, Meizi Chen, Hyunjun Jang, Li Ling Goldston, Brandon Conklin, Inbo Han, Ki‐Bum Lee   +9 more
wiley   +1 more source

Method for Angiographically Guided Fine-Needle Diathermy in the Treatment of Corneal Neovascularization [PDF]

, 2016
Purpose: To describe a method to assess corneal neovascular (CoNV) complexes and identify feeder vessels for selective arterial fine-needle diathermy (FND). Methods: In patients with CoNV, color photography and corneal indocyanine green angiography (ICGA)
Ahmad, S, Brunner, M, Kaye, SB, Romano, V, Steger, B, Willoughby, CE   +5 more
core   +1 more source

AGAPIR: A Novel PIWI‐Interacting RNA Enhancing Post‐Decompression Angiogenesis in Degenerative Cervical Myelopathy

Advanced Science, EarlyView.
The restoration of blood flow following surgical decompression for degenerative cervical myelopathy (DCM) significantly contributes to the amelioration of neurological deficits. This study identifies AGAPIR, an angiogenesis‐associated PIWI‐interacting RNA, enhances angiogenesis and motor function recovery post‐spinal cord decompression in a mouse model
Yongheng Xie, Yiling Peng, Tianyu Qin, Cuimei Chen, Zhenxiao Ren, Naibo Feng, Chungeng Liu, Songlin Peng, Houqing Long   +8 more
wiley   +1 more source

Bevacizumab as a treatment option in gastrointestinal bleeding associated to hereditary hemorrhagic telangiectasia. Case Report

Revista de la Facultad de Medicina, 2019
Introduction: Hereditary Hemorrhagic Telangiectasia (HHT) is an autosomal dominant genetic disease characterized by the presence of arteriovenous malformations in the nasal mucosa, the tips of fingers, and sometimes in the lungs, the gastrointestinal ...
Erwing Castillo, Jeanette Prada-Arismendy   +1 more
doaj   +1 more source

Apolipoprotein E2 and E3, but Not E4, Promote Retinal Pathologic Neovascularization

Investigative Opthalmology & Visual Science, 2017
To determine the relationship between the different isoforms of apolipoprotein E (ApoE) and retinal neovascularization.The concentrations of ApoE and VEGF in vitreous humor samples with either a macular hole (MH), or diabetic macular edema (DME), or proliferative diabetic retinopathy (PDR) with or without intravitreal injection of bevacizumab (IVB ...
Atsushi Kojima, Hideaki Kawakami, Hideaki Hara, Tomomi Masuda, Masamitsu Shimazawa, Kiyofumi Mochizuki, Shinsuke Nakamura, Shinsuke Suemori, Kazuhide Kawase, Yuhei Hashimoto   +9 more
openaire   +3 more sources

Mixed origin of neovascularization of human endometrial grafts in immunodeficient mouse models [PDF]

, 2009
peer reviewedBACKGROUND: In vivo mouse models have been developed to study the physiology of normal and pathologic endometrium. Although angiogenesis is known to play an important role in endometrial physiology and pathology, the origin of neovasculature
A. Beliard, Abulafia, Asahara, Becker, BRUNER-TRAN, C. Galant, Critchley, Debbage, Di Carlo, Donnez, E. Marbaix, Eggermont, F. Frankenne, Fraser, Galili, Galili, Gargett, Gordon, Grummer, Hickey, Hull, J.-M. Foidart, Jaffe, Kawashima, KRIKUN, M. Nisolle, M.-L. Alvarez Gonzalez, McCluggage, Mints, Murphy, Nap, Nisolle, Pe a, Risau, Rydberg, Saito, Smith, Story, Van Cauwenberge, Zeng   +39 more
core   +1 more source

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

Advanced Science, EarlyView.
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen, Min Zhu, Xingyan Fan, Kangjia Lv, Kuan Jiang, Yuchen Zhang, Haoliang Zhang, Xinming Qi, Benjamin TK Lee, Yakun Wan, Gang Wei, Kun Liu, Xun Xu   +12 more
wiley   +1 more source

Biologic response of inguinal hernia prosthetics: A comparative study of conventional static meshes versus 3D dynamic implants [PDF]

, 2015
Despite improvements in prosthetics and surgical techniques, the rate of complications following inguinal hernia repair remains high. Among these, discomfort and chronic pain have become a source of increasing concern among surgeons.
Aasvang, Amato, Amato, Amato, Amato, Amato, Amato, Amato, Amid, Amid, Amid, Amid, Debord, EU Hernia Trialist Collaboration, Kim-Fuchs, Kincaid, Klinge, Klosterhalfen, Klosterhalfen, O'Dwyer, Penkert, Read, Rutkow, Rutkow, Schwab, Tozzi, Valentin   +26 more
core   +1 more source

EETs Reduction Contributes to Granulosa Cell Senescence and Endometriosis‐Associated Infertility via the PI3K/AKT/mTOR Signaling Pathway

Advanced Science, EarlyView.
1) 14, 15‐EET levels were decreased in ovarian granulosa cells, follicular fluid, peritoneal fluid from endometriosis patients. 2) EETs reduction in endometriosis follicular fluid aggravated granulosa cell senescence. 3) ROS reduced 14, 15‐EET levels by upregulating EPHX2 through a mechanism involving histone methylation modification.
Xiang Lin, Weijia Gu, Xiaomei Tong, Mengru Lai, Yi Zhang, Na Liu, Xiaoying Jin, Chao Li, Dong Huang, Feng Zhou, Yongdong Dai, Songying Zhang   +11 more
wiley   +1 more source

Intravitreal aflibercept for the treatment of choroidal neovascularization associated with pathologic myopia: a pilot study

Clinical Ophthalmology, 2016
Andrii R Korol, Oleg S Zadorozhnyy, Volodymyr O Naumenko, Taras B Kustryn, Nataliya V Pasyechnikova The Filatov Institute of Eye Diseases and Tissue Therapy of the National Academy of Medical Sciences of Ukraine, Odessa, Ukraine Purpose: To determine ...
Korol AR, Zadorozhnyy OS, Naumenko VO, Kustryn TB, Pasyechnikova NV   +4 more
doaj