Results 111 to 120 of about 26,618 (266)

Sequential catalytic nanosystem of carbon dots and uricase integrated with polydopamine for therapy of gouty wound ulceration

BMEMat, EarlyView.
Sequential dual‐catalytic treatment of the gout wound ulceration process by CDs‐Uri@PDA. (a) Synthesis steps and morphology of CDs‐Uri@PDA. (b) Sequential treatment process and mechanism of CDs‐Uri@PDA for gout wound ulceration according to (i) uric acid reduction, (ii) antibacterial activity, and (iii) anti‐inflammatory effects.
Yonglan Yang, Yang Yang, Pengpeng Ma, Ruiqi Zhu, Xia Pan, Shaoling Zheng, Bo Chen, Yanli Jin, Youcong Gong, Jie Liu, Tianwang Li, Xu Chen   +11 more
wiley   +1 more source

Inhibition of pathological retinal neovascularization by semaphorin 3A.

Molecular vision, 2013
Pathological retinal angiogenesis is a major cause of vision loss. Semaphorin 3A (Sema3A), a chemorepellent guidance protein, plays crucial roles in neural and vascular patterning. To identify its role in retinal neovascularization, we investigated its antiangiogenic effects.Human umbilical vein endothelial cells (HUVECs) were used for the in vitro ...
Wenzhen, Yu, Yujing, Bai, Na, Han, Fei, Wang, Min, Zhao, Lvzhen, Huang, Xiaoxin, Li   +6 more
openaire   +1 more source

Exosome‐mimetic vesicle‐encapsulated multi‐responsive antibacterial hydrogel core‐shell microneedle patch promotes scarless healing of infected wounds

BMEMat, EarlyView.
The core‐shell microneedle patch VP@FNV‐CuO2‐MN was fabricated by encapsulating n‐CuO2 in a moderately crosslinked PVA/CMCS/Borax4 hydrogel shell and VP‐loaded fibroblast membrane nanovesicles (VP@FNV) in a highly crosslinked PVA/CMCS/Borax6 hydrogel core. Upon application to an infected wound, the acidic microenvironment triggers Fenton‐like reactions
Ziwei Jiang, Huihui Zhang, Lianglong Chen, Zhangfeifan Yang, Sai Cao, Yufang He, Xiaoyang Liu, Siew Yee Wong, Xu Li, Hai Zhou, Ziyan Li, Zijun Zheng, Lei Yang   +12 more
wiley   +1 more source

Unilateral Optic Disc Neovascularization in a Patient with Optic Disc Pit Depending on Proliferative Diabetic Retinopathy

Bezmiâlem Science
Optic disc pit is an excavation of the optic disc that usually develops congenital or rarely acquired, mostly located in the inferotemporal part of the disc. It is usually asymptomatic but sometimes might be symptomathic with maculopathy development.
Atilla ŞAHİN, Cansu EKİNCİ ASLANOĞLU, Hakan ÖZDEMİR   +2 more
doaj   +1 more source

Choroidal neovascularization management in pathological myopia

, 2012
New approaches in the diagnosis and therapy of myopic Choroidal neovascularization (CNV). Long-tem effects of anti-VEGF therapy for subfoveal myopic CNV. Best treatment drug: Bevacizumab versus Ranibizumab. Effects of treatment regimen. Effects of myopic CNV location (Juxtafoveal versus Extrafoveal myopic CNV).
openaire   +1 more source

Digital workflow to assess healing after acellular dermal matrix exposure in root coverage: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background This case report describes 18‐month clinical and digital outcomes after bilateral treatment of multiple gingival recessions using coronally advanced flap plus acellular dermal matrix (ADM). Methods A 46‐year‐old woman with multiple maxillary recessions received bilateral surgery.
Edgar Daniel Vargas‐Quiroga, Ana Carolina Duarte Firmino, Débora S. F. Sávio, Rhayssa Tritula Barini, Juliana Jendiroba Faraoni, Mario Taba‐Jr, Bruna S. H. Tonin, Arthur Belém Novaes Junior   +7 more
wiley   +1 more source

Targeting the Mitochondrial Chaperone TRAP1 Alleviates Vascular Pathologies in Ischemic Retinopathy

Advanced Science
Activation of hypoxia‐inducible factor 1α (HIF1α) contributes to blood‐retinal barrier (BRB) breakdown and pathological neovascularization responsible for vision loss in ischemic retinal diseases.
So‐Yeon Kim, Nam Gu Yoon, Jin Young Im, Ji Hye Lee, Juhee Kim, Yujin Jeon, Young Jae Choi, Jong‐Hwa Lee, Akiyoshi Uemura, Dong Ho Park, Byoung Heon Kang   +10 more
doaj   +1 more source

Spatial Mismatch Between Angiographic Obstruction and Plaque Destabilization in Acute Coronary Syndromes: A Conceptual Narrative Review

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT The identification of the “culprit lesion” in acute coronary syndromes (ACS) traditionally relies on coronary angiography, assuming that the most severe stenosis, abrupt occlusion, or largest filling defect marks the site of plaque destabilization.
Fernando Quevedo‐Candela, Olivier F. Bertrand, Pedro Cepas‐Guillén, Jean‐Pierre Déry, David García‐Labbé, Andrés Ruhl, Eduardo Flores‐Umanzor, Tomas Cieza   +7 more
wiley   +1 more source

Halogenated Tryptophans Improve Integrin αVβ6 Affinity of Cyclic RGD Peptides and Provide Handles for Late‐Stage Derivatization

Chemistry – A European Journal, EarlyView.
Lighting up αVβ6: Halotryptophan engineering converts an RGD scaffold into a modular αVβ6 ligand platform, enabling picomolar affinity and late‐stage functionalization. The resulting probes combine high selectivity with fluorescence for FACS and tumor imaging.
Beate Nachtigall, Caroline Brinkmann, Jana Langosch, Anke Nieß, Norbert Sewald   +4 more
wiley   +1 more source

Microbiome and Tumor Microenvironment Interactions: Advances From Ecological Niches to Precision Oncology

Cancer Nexus, EarlyView.
Tumor‐associated microbiota occupies spatially organized ecological niches and influence cancer progression by reshaping tumor‐cell signaling, metabolism, immunity, stromal remodeling, and therapeutic response. Integrating microbiome‐derived biomarkers, targeted microbial interventions, spatial multi‐omics, longitudinal monitoring, and AI may enable ...
Yiwen Zhang, Ji'an Liu, Jing Li, Xue Liu, Yang Su, Peng Luo, Yuhan Zhang, Zhengrui Li   +7 more
wiley   +1 more source