Results 131 to 140 of about 1,067,090 (283)
Animal Models and Experimental Medicine, EarlyView.Based on the inducible pericyte ablation model, we discovered that Pdgfrb+ pericytes regulate glioblastoma (GBM) growth. Using the pericyte lineage tracing model, we revealed their dynamic behavior during GBM angiogenesis. Proteomic analysis combined with pericyte RNA analysis based on human single‐cell data demonstrated cross‐species conserved ...
Qinghong Wang +5 more
wiley +1 more source
Irisin‐Loaded Dissolving Microneedles Promote Rapid Wound Healing
Advanced NanoBiomed Research, EarlyView.Schematic of effective wound healing facilitated by water‐degradable microneedles loaded with irisin that enhance irisin penetration, fibroblast migration, differentiation, and extracellular matrix synthesis at the wound site. Irisin, an exercise‐induced myokine with anti‐inflammatory and regenerative activity, is incorporated into dissolving poly ...
Yu‐Chi Pan +6 more
wiley +1 more source
Pegaptanib sodium for ocular vascular disease
Indian Journal of Ophthalmology, 2007 Pegaptanib sodium (Macugen) is a selective RNA aptamer that inhibits vascular endothelial growth factor (VEGF) 165 , the VEGF isoform primarily responsible for pathologic ocular neovascularization and vascular permeability, while sparing the ...
Shukla Dhananjay +3 more
doaj
Advanced NanoBiomed Research, EarlyView.Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo +2 more
wiley +1 more source
Bezmiâlem ScienceOptic disc pit is an excavation of the optic disc that usually develops congenital or rarely acquired, mostly located in the inferotemporal part of the disc. It is usually asymptomatic but sometimes might be symptomathic with maculopathy development.
Atilla ŞAHİN +2 more
doaj +1 more source
Choroidal neovascularization secondary to pathological myopia
World Journal of Ophthalmology, 2014 Chui Ming Gemmy Cheung, Kelvin Teo
openaire +2 more sources
Arthritis &Rheumatology, Accepted Article.Objectives Giant cell arteritis (GCA) is a large‐vessel vasculitis, potentially causing complications such as blindness and strokes. This study aims to gain insights into the pathogenesis of GCA by identifying specific DNA methylation signatures in the arterial tissue of patients with this vasculitis.
Gonzalo Borrego‐Yaniz +18 more
wiley +1 more source
Targeting the Mitochondrial Chaperone TRAP1 Alleviates Vascular Pathologies in Ischemic Retinopathy
Advanced ScienceActivation of hypoxia‐inducible factor 1α (HIF1α) contributes to blood‐retinal barrier (BRB) breakdown and pathological neovascularization responsible for vision loss in ischemic retinal diseases.
So‐Yeon Kim +10 more
doaj +1 more source
Cost–benefit analysis of screening programme for diabetic retinopathy in Bulgaria
British Journal of Clinical Pharmacology, EarlyView.Aims Late‐diagnosed diabetic retinopathy (DR) is difficult and expensive to treat. Screening programmes can identify the disease early and reduce the costs of its future treatment. This study aims to analyse the cost–benefit of screening programmes for DR.
Iva Nenkova +5 more
wiley +1 more source
Antibacterial hydrogel: The sniper of chronic wounds
BMEMat, EarlyView.The treatment of chronic wounds has always been an important challenge in the medical field. We focus on hydrogels not only because they provide a moist healing environment but also because compared with traditional dressings, they can effectively prevent and treat infections, reduce wound pain and scar formation.
Shengtai Bian +6 more
wiley +1 more source