Results 141 to 150 of about 34,072 (291)

Two years follow-up outcome of verteporfin therapy for subfoveal choroidal neovascularization in pathologic myopia in Indian eyes

Indian Journal of Ophthalmology, 2008
Context: In India, refractive errors are a major cause of treatable blindness. Population surveys in southern India have shown prevalence of high myopia to be 4.32-4.54%. Photodynamic therapy (PDT) for choroidal neovascularization (CNV) caused by
Hussain Nazimul, Khanna Rohit, Das Taraprasad, Narayanan Raja, Sunday Oluleye, Bansal Azad, Reddy Rajeev   +6 more
doaj  

Dual‐Pedicle Tissue‐Engineered Trachea Promotes Biomimetic Cartilaginous Framework, Vascularization, and Epithelial Lining for Long‐Segment Tracheal Reconstruction

Advanced Science, EarlyView.
Overcoming the limitations of conventional grafts, a biomimetic trachea with two independent vascular pedicles enables rapid integration and sustained patency. This approach markedly improves survival rates, restores the epithelial barrier, and promotes regenerative pathways, presenting a transformative paradigm for clinical application.
Ziming Wang, Yuming Wang, Zihao Chen, Erji Gao, Liang Guo, Juanjuan Li, Siqiang Zheng, Jiaoyu Yi, Zhe‐Sheng Chen, Bo Tao   +9 more
wiley   +1 more source

Reinstating Niche Failure in Diabetic Cranial Defects via Chronotaxic Signal‐Amplifying Fluidic Biomimetic Hydrogel

Advanced Science, EarlyView.
An in situ moldable GelSSO/PDA@SDF hydrogel functions as a chronotaxic signal‐amplifying biomimetic niche to restore regenerative failure in diabetic cranial defects. By sequentially releasing SDF‐1α‐loaded PDA nanoparticles and osteoinductive oligodeoxynucleotides, it orchestrates immunomodulation, progenitor recruitment, angiogenesis, and ...
Yingji Mao, Yu Chen, Runlin Fan, Pengzhen Zhuang, Hongbo Zhang, Pinghui Zhou   +5 more
wiley   +1 more source

Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined

Aggregate, EarlyView.
Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei, Xikai Wang, Zhuang Hu, Jierui Yan, Xiaobo Wang, Haoran Wang, Ya Hou, Pengfei Zhang, Qihang Ding   +8 more
wiley   +1 more source

Microgels for 3D Biofabrication

Aggregate, EarlyView.
This review highlights microgels as a versatile platform advancing biomanufacturing and tissue regeneration. It details their fabrication methods, core functions (bioprinting inks, suspension support baths, porous sacrificial scaffolds), and pivotal applications (drug delivery, dynamic cell culture microenvironments, tissue engineering scaffolds ...
Ting Xie, Huaibin Wang, Jieting Li, Leyan Xuan, Farzana Nazir, Long Chen, Zeyu Luo, Mian Wang, Yingling Miao, Dongyang Zhang, Wanlu Li, Guosheng Tang   +11 more
wiley   +1 more source

Biomimetic Thalidomide Nanoparticles: Targeted and Sustained Therapeutic Strategy for Oxygen‐Induced Retinopathy

Aggregate, EarlyView.
Magnesium acetyl taurate and thalidomide co‐assembled nanoparticles (MT NPs) are prepared via Super‐stable Pure Nanomedicine Formulation Technology (SPFT), and the NPs are further coated with transferrin‐modified cell membrane vesicles to construct Tfm@MT nanomedicine for oxygen‐induced retinopathy treatment.
Mengdie Li, Shundong Cai, Jinfa Ye, Lang Ke, Guanxiong Yang, Shaopan Wang, Cuiting Chen, Peixin Cai, Hui Liu, Xingyuan Wei, Songyi Wang, Yun Han, Shilong Shao, Min Su, Gang Liu, Chengchao Chu   +15 more
wiley   +1 more source

Differences between pathologic and non-pathologic high myopia in 4-year outcomes of anti-VEGF therapy for macular neovascularization

Scientific Reports
This retrospective observational study aimed to investigate the difference in 4-year outcomes of ranibizumab or aflibercept therapy for macular neovascularization (MNV) with high myopia between pathologic myopia (PM) and non-PM.
Yuki Honda, Manabu Miyata, Masahiro Miyake, Masayuki Hata, Shogo Numa, Yuki Mori, Sotaro Ooto, Hiroshi Tamura, Naoko Ueda-Arakawa, Yuki Muraoka, Ayako Takahashi, Keina Sado, Ai Kido, Akitaka Tsujikawa   +13 more
doaj   +1 more source

Mainstream Artificial Intelligence Technologies in Contemporary Ophthalmology

Advanced Intelligent Systems, EarlyView.
This review explores the latest artificial intelligence (AI) technologies in ophthalmology, focusing on four key data types: medical imaging, electronic health records, robotic‐assisted surgery, and genomics. It examines the structural features, use cases, clinical goals, and evaluation metrics of various AI algorithms, while also introducing emerging ...
Shiqi Yin, Lei Wang, Shanjun Wu, Jiewei Jiang, Wei Qiang, Yangyang Wang, Shihong Wang, Yi Shao, Wei Chen, Zhongwen Li   +9 more
wiley   +1 more source

Effects of expressions of VEGF, VEGF ⁃ C, VEGFR ⁃ 3 on interstitial angiogenesis and tumor cell proliferation in human gliomas

Chinese Journal of Contemporary Neurology and Neurosurgery, 2010
Objective To explore the changes of vascular endothelial growth factor (VEGF), vascular endothelial growth factor⁃C (VEGF⁃C) and vascular endothelial growth factor receptor⁃3 (VEGFR⁃3) expression and their impacts on tumor cell proliferation and ...
Su⁃qin CHEN, Yong⁃jing HE, Shi⁃zhu YU, Yang SONG, Tong⁃ling AN, Cui⁃yun SUN, Qian WANG   +6 more
doaj  

Mast cells promote choroidal neovascularization in a model of age-related macular degeneration

Journal of Neuroinflammation
‘Wet’ age-related macular degeneration (AMD) is characterized by pathologic choroidal neovascularization (CNV) that destroys central vision. Abundant evidence points to inflammation and immune cell dysfunction in the progression of CNV in AMD. Mast cells
Rabah Dabouz, Pénélope Abram, Jose Carlos Rivera, Sylvain Chemtob   +3 more
doaj   +1 more source