Results 1 to 10 of about 34,421 (331)

Specific ablation of PDGFRβ-overexpressing pericytes with antibody-drug conjugate potently inhibits pathologic ocular neovascularization in mouse models [PDF]

Communications Medicine, 2021
Lee et al. use an antibody-drug conjugate to treat pathologic ocular neovascularization in mouse models. The antibody-drug conjugate targets PDGFRβ-expressing pericytes, with similar therapeutic effects to an anti-VEGF agent and with limited unwanted ...
Seok Jae Lee, Soohyun Kim, Dong Hyun Jo, Chang Sik Cho, Su Ree Kim, Dongmin Kang, Jisu Chae, Duck Kyun Yoo, Suji Ha, Junho Chung, Jeong Hun Kim   +10 more
doaj   +2 more sources

Use of ranibizumab for the treatment of subretinal neovascularization in pathologic myopia: a prospective study

Journal of Ophthalmology, 2016
Purpose: To determine the efficacy of ranibizumab as a treatment for subretinal neovascularization (SRNV) in pathologic myopia. Materials and Methods: This was an uncontrolled, prospective cohort study, involving 66 pathologic myopic eyes (65 patients)
О.M. Blavatska, T.B. Kustry, A.R. Korol
doaj   +2 more sources

ANTI-ANGIOGENIC THERAPY IN PATIENTS WITH PATHOLOGIC MYOPIA AND CHOROIDAL NEOVASCULARIZATION

Acta Biomedica Scientifica, 2016
Purpose of the study: to study the efficacy and safety of Ranibizumab in patients with pathologic myopia and choroidal neovascularization (CNV). 22 patients (22 eyes) with myopic CNV were included in the study.
S. A. Korotkikh, E. V. Bobykin, G. V. Zhiborkin, A. Y. Anashkin, A. V. Berezin   +4 more
doaj   +3 more sources

Two years follow-up outcome of verteporfin therapy for subfoveal choroidal neovascularization in pathologic myopia in Indian eyes

Indian Journal of Ophthalmology, 2008
Context: In India, refractive errors are a major cause of treatable blindness. Population surveys in southern India have shown prevalence of high myopia to be 4.32-4.54%. Photodynamic therapy (PDT) for choroidal neovascularization (CNV) caused by
Hussain Nazimul, Khanna Rohit, Das Taraprasad, Narayanan Raja, Sunday Oluleye, Bansal Azad, Reddy Rajeev   +6 more
doaj   +2 more sources

Targeting ATF6 reduces pathological neovascularization and improves visual outcomes in retinal disease models. [PDF]

Sci Rep
Bradley A, Park S, Park S, Kim K, Galdamez A, Min H, Diaz-Aguilar MS, Hartnett ME, Lee EJ, Lin JH.   +9 more
europepmc   +2 more sources

Vascular endothelial growth factor and KIT expression in relation with microvascular density and tumor grade in supratentorial astrocytic tumors [PDF]

Acta Cirúrgica Brasileira, 2013
PURPOSE: To evaluate the relationship between microvascular density and the expression of vascular endothelial growth factor (VEGF) and KIT as possible markers of angiogenic stimulus in astrocytic tumors and correlate it with histopathological grading ...
Thaís Heinke, Kleber Simões do Espiríto Santo, Adhemar Longatto Filho, João Norberto Stavale   +3 more
doaj   +3 more sources

Topical Nanoemulsion of a Runt-related Transcription Factor 1 Inhibitor for the Treatment of Pathologic Ocular Angiogenesis

Ophthalmology Science, 2022
Purpose: To test the efficacy of runt-related transcription factor 1 (RUNX1) inhibition with topical nanoemulsion containing Ro5-3335 (eNano-Ro5) in experimental ocular neovascularization. Design: Preclinical experimental study.
Santiago Delgado-Tirado, MD, Lucia Gonzalez-Buendia, MD, Miranda An, BA, Dhanesh Amarnani, MS, Daniela Isaacs-Bernal, BSc, Hannah Whitmore, PhD, Said Arevalo-Alquichire, PhD, David Leyton-Cifuentes, BME, Jose M. Ruiz-Moreno, MD, PhD, Joseph F. Arboleda-Velasquez, MD, PhD, Leo A. Kim, MD, PhD   +10 more
doaj   +1 more source

Correlation between the expression of vegf and survival in osteosarcoma [PDF]

Acta Ortopédica Brasileira, 2014
Objective: To present a series of 50 consecutive patients with non-metastatic extremity osteosarcoma, and attempt to correlate expression of the vascular endothelial growth factor (VEGF) protein in biopsy tissue to their prognosis regarding overall ...
André Mathias Baptista, André Ferrari De França Camargo, Renée Zon Filippi, Cláudia Regina Gomes Cardim Mendes De Oliveira, Raymundo Soares De Azevedo Neto, Olavo Pires De Camargo   +5 more
doaj   +1 more source

MicroRNA-18a-5p Administration Suppresses Retinal Neovascularization by Targeting FGF1 and HIF1A

Frontiers in Pharmacology, 2020
Pathologic ocular neovascularization commonly results in visual impairment or even blindness in numerous fundus diseases, including proliferative diabetic retinopathy (PDR), retinopathy of prematurity (ROP), and age-related macular degeneration (AMD ...
Ji-Tian Guan, Xin-Xin Li, De-Wei Peng, Wen-Meng Zhang, Jia Qu, Fan Lu, Fan Lu, Robert J. D’Amato, Robert J. D’Amato, Zai-Long Chi, Zai-Long Chi   +10 more
doaj   +1 more source

Successful Use of Conbercept to Treat Choroidal Neovascularization: A Case Report

Case Reports in Ophthalmology, 2022
Chronic urticaria is a dermatological condition characterized by the appearance of wheals or angioedema longer than 6 weeks. It could cause serious complications such as laryngeal edema, vasculitis, and diarrhea.
Jin Yang, Zheng Liu, Tao Liu
doaj   +1 more source