Results 21 to 30 of about 34,421 (331)

An Endostatin-lentivirus (ES-LV)-EPC gene therapy agent for suppression of neovascularization in oxygen-induced retinopathy rat model

open access: yesBMC Molecular and Cell Biology, 2020
Background Transplantation of gene transfected endothelial progenitor cells (EPCs) has provided novel methods for tumor neovascularization therapy but not for ocular disease therapy.
Jing Ai   +4 more
doaj   +1 more source

Evaluation of a novel deep learning based screening system for pathologic myopia [PDF]

open access: yesInternational Journal of Ophthalmology, 2023
AIM: To evaluate the clinical application value of the artificial intelligence assisted pathologic myopia (PM-AI) diagnosis model based on deep learning. METHODS: A total of 1156 readable color fundus photographs were collected and annotated based on the
Pei-Fang Ren   +5 more
doaj   +1 more source

Gut microbiota influences pathological angiogenesis in obesity‐driven choroidal neovascularization [PDF]

open access: goldEMBO Molecular Medicine, 2016
AbstractAge‐related macular degeneration in its neovascular form (NV AMD) is the leading cause of vision loss among adults above the age of 60. Epidemiological data suggest that in men, overall abdominal obesity is the second most important environmental risk factor after smoking for progression to late‐stage NV AMD.
Elisabeth M. M. A. Andriessen   +6 more
openalex   +4 more sources

Sema3f Protects Against Subretinal Neovascularization In Vivo

open access: yesEBioMedicine, 2017
Pathological neovascularization of the outer retina is the hallmark of neovascular age-related macular degeneration (nAMD). Building on our previous observations that semaphorin 3F (Sema3f) is expressed in the outer retina and demonstrates anti ...
Ye Sun   +17 more
doaj   +1 more source

Angiogenesis in squamous precancerous cervical lesions [PDF]

open access: yesVojnosanitetski Pregled, 2007
Background/Aim. Vascularisation is one of basic tumor's characteristics. Neoangiogenesis starts at the stage of the dysplastic epithelial changes, thus before the progression into invasive lesion. This study was designed to determine the relation between
Panjković Milan   +1 more
doaj   +1 more source

Arterial pathology in canine mucopolysaccharidosis-I and response to therapy. [PDF]

open access: yes, 2011
Mucopolysaccharidosis-I (MPS-I) is an inherited deficiency of α-L-iduronidase (IdU) that causes lysosomal accumulation of glycosaminoglycans (GAG) in a variety of parenchymal cell types and connective tissues.
Dickson, Patricia I   +6 more
core   +3 more sources

Co-existent choroidal neovascular membrane and macular hole in pathologic myopia:a long follow-up clinical outcome and literature review

open access: yesInternational Journal of Ophthalmology, 2013
Choroidal neovascularization (CNV) is an uncommon complication associated with a macular hole. In this case report of a rare condition, we present a pathologic myopia patient with a co-existent macular hole and choroidal neovascular membrane. The patient
Zhi-Qing Chen   +4 more
doaj   +1 more source

Oxidative and Nitrosative Stress in Age-Related Macular Degeneration: A Review of Their Role in Different Stages of Disease

open access: yesAntioxidants, 2021
Although the exact pathogenetic mechanisms leading to age-related macular degeneration (AMD) have not been clearly identified, oxidative damage in the retina and choroid due to an imbalance between local oxidants/anti-oxidant systems leading to chronic ...
Caterina Toma   +4 more
doaj   +1 more source

Long-term follow-up of myopic choroidal neovascularization treated with ranibizumab [PDF]

open access: yes, 2011
PURPOSE: To evaluate the long-term safety and efficacy of intravitreal ranibizumab in the treatment of myopic choroidal neovascularization (CNV). METHODS: Three-year retrospective, nonrandomized, interventional case series.
Cachulo, ML   +6 more
core   +1 more source

El cáncer en la función mitocondrial

open access: yesRevista de la Facultad de Medicina, 2018
Metabolism alterations are associated with the loss of mitochondrial function in tumor cells. Current research discuss whether such loss is evident in function itself, or if cells can provide maximum stability to its functions. More studies are needed to
Sofía Isabel Freyre-Bernal   +4 more
doaj   +1 more source

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