Results 31 to 40 of about 34,421 (331)
Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future [PDF]
, 2019 Ocular diseases cause visual impairment and blindness, imposing a devastating impact on quality of life and a substantial societal economic burden. Many such diseases lack universally effective pharmacotherapies.
Corson, Timothy W., Park, Bomina
core +1 more source
Inhibition of pathologic retinal neovascularization by -defensins
Blood, 2005 Proliferative retinopathies, such as those complicating prematurity and diabetes, are major causes of blindness. A prominent feature of these retinopathies is excessive neovascularization, which is orchestrated by the hypoxia-induced vascular endothelial growth factor (VEGF) stimulating endothelial cells and the integrin-mediated adhesive interactions ...
Klaus T. Preissner +9 more
openaire +4 more sources
A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization
Cell Reports, 2019 Summary: Id helix-loop-helix (HLH) proteins (Id1–4) bind E protein bHLH transcription factors, preventing them from forming active transcription complexes that drive changes in cell states.
Paulina M. Wojnarowicz +32 more
doaj +1 more source
Angiofluorographic Characteristics of Choroidal Neovascularization associated with Pathologic Myopia
romanian journal of ophthalmology, 2020 Purpose: To evaluate the incidence of choroidal neovascularization (CNV) in high myopic patients who experienced recent visual loss and to describe the characteristics of CNV that develop as a complication of pathologic myopia and were detected by fluorescein angiography (FA).
Irina Stefan, Anca Tomi
openaire +3 more sources
Jornal Vascular Brasileiro, 2019 Background Anti-angiogenic regulators may have therapeutic implications for onset and progression of atherosclerosis. Objectives To demonstrate histological changes secondary to the use of bevacizumab in the aorta of pigs after interruption of flow in ...
Cyro Castro Júnior +1 more
doaj +1 more source
Management of Myopic Maculopathy: A Review
Türk Oftalmoloji Dergisi, 2023 Myopia, including pathologic myopia, has seen a significant increase in prevalence in recent years. It is a significant cause of irreversible vision loss worldwide and prediction models demonstrate the substantial future impact on the population.
William J. Anderson, Levent Akduman
doaj +1 more source
BMC Ophthalmology, 2021 Background To evaluate the 12-month efficacy and safety of intravitreal conbercept for myopic choroidal neovascularization (CNV). Methods A retrospective, observational study.
Xin Nie +3 more
doaj +1 more source
Frontiers in Medicine, 2022 Myopia represents a major socioeconomic burden with an increasing prevalence worldwide. Pathologic myopia refers to myopic patients with structural changes in the posterior pole including different patterns of chorioretinal atrophy, choroidal ...
Roberto Gallego-Pinazo +2 more
doaj +1 more source
Intravitreal anti-VEGF therapy for choroidal neovascularisation secondary to pathological myopia: 4-year outcome [PDF]
, 2013 OBJECTIVE: To report the visual outcome after 4-year follow-up in a series of highly myopic eyes with choroidal neovascularisation (CNV) treated with antivascular endothelial growth factor (anti-VEGF) drugs.
Arias, L +4 more
core +1 more source
Thymidine phosphorylase and its possible correlation with the lung cancer phenotype features
Patologìâ, 2015 The tumor phenotype investigation is necessary for lung cancer drug therapy optimization. For this purpose is perspective to use the biochemical markers of angiogenesis. Thymidine phosphorylase may be one of them. Aim. The aim of study was to evaluate
E. M. Bakurova +5 more
doaj +1 more source