Aldehyde Dehydrogenase 2 Gene Polymorphism and Alcohol Consumption Are Associated With Nephrolithiasis in a Chinese Population [PDF]
Molecular Genetics & Genomic MedicineBackground Nephrolithiasis is a common urological disorder and has become a significant global public health issue. Aldehyde dehydrogenase 2 (ALDH2), an important endogenous antioxidant enzyme involved in alcohol metabolism, has been shown to exert ...
Tao Liu +11 more
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Multiomics Mendelian randomization integrating pQTL, eQTL and mQTL data revealed BTN3A2 as a potential drug target for nephrolithiasis [PDF]
Scientific ReportsNephrolithiasis has a high recurrence rate and imposes a heavy burden on patients and society. Therefore, there is an urgent need to explore new effective targets for nephrolithiasis prevention and treatment.
Shanshan Sun +4 more
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Prevalence and related factors of nephrolithiasis among medical staff in Qingdao, China: a retrospective cross-sectional study [PDF]
BMC NephrologyBackground Certain occupations may predispose individuals to urolithiasis, a multi-factorial disease. The study aimed to evaluate the prevalence and related factors of nephrolithiasis in medical staff in Qingdao, China.
Lei Guo +7 more
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Prevalence and risk factors for nephrolithiasis in adults with cystic fibrosis: A retrospective cohort study. [PDF]
PLoS ONEBackgroundCalcium oxalate nephrolithiasis is more common in persons living with cystic fibrosis (PwCF) than in the general population. A primary risk factor is exocrine pancreatic insufficiency (EPI) causing enteral hyperoxaluria.
Da Yeon Ryoo +12 more
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Urology Case Reports, 2023 The incidence of nephrolithiasis in children ranges from 5 to 10% in developing countries. Etiology of nephrolithiasis in children remains largely unknown, so metabolic evaluation is indicated in all case, because of potential morbidity and recurrence ...
Rizky Ramdhani +6 more
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Effects of sodium-glucose co-transporter-2 inhibitors on the risk of nephrolithiasis and urinary tract infections in Thai patients with type 2 diabetes: a hospital-based cohort study [PDF]
Diabetology & Metabolic SyndromeBackground Nephrolithiasis is a multifactorial disease with many contributing factors varying across races, ethnicities, and sociocultural backgrounds. Diabetes is a significant independent risk factor for nephrolithiasis.
Thitiya Lukkunaprasit +10 more
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The -160C>a polymorphism in E-cadherin is associated with the risk of nephrolithiasis. [PDF]
PLoS ONE, 2013 Nephrolithiasis is a common disorder worldwide. E-cadherin (CDH1) is involved in epithelial cell-cell interactions and plays important roles in the etiology of nephrolithiasis.
Mingyue Tan +4 more
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Life, 2022 The association of gout with nephrolithiasis has been suggested. The current study investigated the risk of nephrolithiasis in patients with gout.
So Young Kim +7 more
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Nephrolithiasis, kidney failure and bone disorders in Dent disease patients with and without CLCN5 mutations [PDF]
, 2015 open9noDent disease (DD) is a rare X-linked recessive renal tubulopathy characterised by low-molecular-weight proteinuria (LMWP), hypercalciuria, nephrocalcinosis and/or nephrolithiasis. DD is caused by mutations in both the CLCN5 and OCRL genes.
Angela D’Angelo +9 more
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Современная ревматология, 2011 output The paper describes current ideas on the pathogenesis and treatment of nephrolithiasis, virtually a constant attendant of gout. The prevalence of nephrolithiasis is reported to be increasing worldwide.
V G Barskova, M V Mukagova
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