Results 71 to 80 of about 32,828 (188)

Chemotherapy in nephrolithiasis.

open access: yesIsrael journal of medical sciences, 1971
Isr J Med ...
Timmermann, A., Kallistratos, G.
openaire   +3 more sources

Challenges in Managing Pregnancy in Patients With Fructose 1, 6‐Bisphosphatase Deficiency: A Single‐Centre Experience

open access: yesJIMD Reports, Volume 67, Issue 5, September 2026.
ABSTRACT Fructose‐1,6‐bisphosphatase deficiency is a rare inherited metabolic disorder of gluconeogenesis characterized by recurrent hypoglycemia and lactic acidosis, typically triggered by inadequate glucose intake or increased consumption of fructose, sucrose, or sorbitol.
Raashda A. Sulaiman   +6 more
wiley   +1 more source

Clinical Molecular Investigation of Encephalitozoon cuniculi in Pet Rabbits: Early Detection of Potential Risk for Animal and Human Infection

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
This study assesses the presence, genotypes and clinical signs of E. cuniculi infection in pet rabbits in Slovenia. Molecular analysis reveals the presence of E. cuniculi DNA (Genotype I) in 14.98% rabbit urine samples, mostly in rabbits with signs of urinary tract disorders.
Maruša Škrbec   +8 more
wiley   +1 more source

Potential metabolic pathways of nephrolithiasis mediated by occupational cadmium exposure

open access: yes环境与职业医学
BackgroundLong-term cadmium exposure is a risk factor for nephrolithiasis; however, the mechanisms underlying cadmium-mediated nephrolithiasis remain unclear.ObjectiveTo investigate the potential metabolic pathways involved in nephrolithiasis induced by ...
Yaotang DENG   +9 more
doaj   +1 more source

G6PC Downregulation Promotes Renal Calcium Oxalate Stone Formation via Lactate‐Induced SNAIL1 K206 Lactylation and Epithelial‐Mesenchymal Transition

open access: yesAdvanced Science, Volume 13, Issue 43, 3 August 2026.
In renal calcium oxalate stone formation, G6PC downregulation leads to lactate accumulation. This lactate mediates CBP/p300‐dependent lactylation of SNAIL1 at K206, promoting its nuclear translocation. Nuclear SNAIL1 activates the TGF‐β/SMAD3 pathway, driving epithelial‐mesenchymal transition and fibrosis, which ultimately facilitates crystal ...
Kai Liu   +16 more
wiley   +1 more source

The comparison of ultrasound and non-contrast helical computerized tomography for children nephrolithiasis detection

open access: yesUrology Annals, 2014
Aims: Nephrolithiasis is less common in children than adults, but its diagnosis and management in children may be more perplexing. In this article, we compare two imaging ultrasound (US) and non-contrast helical computerized tomography (CT) for diagnosis
Majid Malaki
doaj   +1 more source

Herba Lysimachiae Polysaccharide‐Modified Selenium Nanoparticles Alleviate Oxidative Injury in Kidney Stones via TOMM22‐Regulated Mitophagy Activation

open access: yesAdvanced Science, Volume 13, Issue 46, 17 August 2026.
HLP‐SeNPs, a Lysimachia christinae polysaccharide‐modified selenium nanoparticle, treat kidney stones by downregulating TOMM22 expression, which reduces PINK1 translocation into mitochondria and promotes its retention on the outer mitochondrial membrane.
Junyi Yang   +10 more
wiley   +1 more source

Pathogenesis of Nephrolithiasis [PDF]

open access: yesJournal of Urology, 2013
Much has been learned in the last decade regarding the initial steps of crystal deposition and ultimate stone formation. There appear to be 3 basic pathways for crystal formation in the upper urinary tract. The first and most common pathway is the overgrowth of calcium oxalate on suburothelial deposits of hydroxyapatite, so-called Randall plaque.1 This
openaire   +2 more sources

A Metabolomic Signature Predicts Gout Flare Clinical Outcome Associated With Colchicine Prophylaxis

open access: yesArthritis &Rheumatology, Volume 78, Issue 8, Page 1765-1775, August 2026.
Objective This study investigated that serum metabolomics, before urate‐lowering therapy (ULT) initiation, could serve as a biomarker for responsiveness to colchicine prophylaxis in patients with gout commencing treat‐to‐target ULT. Methods We studied a multicenter prospective cohort (n = 409) initiating treat‐to‐target ULT plus colchicine prophylaxis.
Wenyan Sun   +13 more
wiley   +1 more source

Impact of empiric potassium supplementation on mortality, sudden cardiac arrest and stroke in furosemide initiators

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2924-2936, August 2026.
Aim A prior non‐randomized study suggests that potassium supplementation may improve survival among furosemide initiators, and a randomized trial suggests that salt substitutes containing potassium might lower stroke risk. We conducted a retrospective cohort study using health‐care data to confirm or refute these associations among new users of ...
Thanh Phuong Pham Nguyen   +8 more
wiley   +1 more source

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