Results 81 to 90 of about 32,828 (188)
Our understanding of the molecular basis of cystinuria has deepened as the result of the causative genes, SLC3A1 and SLC7A9, being identified. The proteins coded for by these genes form a heterodimer responsible for reabsorption of filtered cystine in the proximal tubule. Failure of this transport system to be targeted to the apical membrane, as in the
Fattah, Hasan +2 more
openaire +2 more sources
ABSTRACT In patients with familial adenomatous polyposis, intra‐abdominal desmoid tumors should be recognized as a rare but important cause of ureteral obstruction and obstructive pyelonephritis. Prompt cross‐sectional imaging, early recognition, and multidisciplinary management are essential for preserving renal function, treating infection, and ...
Alireza Mehrban +5 more
wiley +1 more source
Nucleotide Metabolism in Health and Disease
Nucleotide metabolism, including de novo synthesis, salvage pathways, and catabolism, when dysregulated contributes to cancer, immune disorders, metabolic and urological diseases, and radiation injury. Metabolites such as adenosine, cGAMP, NAD, and cAMP and enzymes like RNR are promising therapeutic targets and biomarkers.
Xiaoying Zhao +7 more
wiley +1 more source
Background Iron deficiency anemia is a common finding in women of child-bearing age. Pica, or the ingestion of non-food or non-nutritive items, is a well-known manifestation of iron deficiency. A high sodium diet increases risk for nephrolithiasis.
Brittany Rogers +4 more
doaj +1 more source
ABSTRACT Hyperuricemia, characterized by elevated serum uric acid (SUA) levels, is increasingly recognized as a pathological contributor to renal injury through oxidative stress, inflammation, and apoptosis. Hirudin, a thrombin inhibitor derived from leech saliva, has recently been noted for its anti‐inflammatory properties, yet its role in ...
Yingxue Zhao +8 more
wiley +1 more source
Nephrolithiasis induced end stage renal disease in patients on hemodialysis in Baghdad (A Multicenter study) [PDF]
Background: Kidney stones are the third most common disease of the urinary system. Nephrolithiasis still remains underappreciated cause of end stage renal disease.
Ali J. Hashim Al Saedi +2 more
doaj
Upper Urinary Tract Stone Disease: Practical Guidance for Early Assessment and Management
ABSTRACT Upper urinary tract stone disease is a common urological condition with high recurrence rates and a significant healthcare burden. Many patients initially present in community or primary care settings, where early assessment and triage influence patient safety, referral timing and subsequent urological management.
Matthew Kwon, Avi Raman
wiley +1 more source
Abstract The guinea pig (Cavia porcellus) is a small rodent commonly kept as a companion animal in exotic pet practice, with reproductive disorders that commonly affect entire females. Among these, ovarian cysts are particularly prevalent in middle‐aged to older animals. This case report describes the use of a right horizontal dorsolateral approach for
Marcus Vinícius Lage Silva Giaculi Marques +4 more
wiley +1 more source
Background Certain occupations may predispose individuals to urolithiasis, a multi-factorial disease. The study aimed to evaluate the prevalence and related factors of nephrolithiasis in medical staff in Qingdao, China.
Lei Guo +7 more
doaj +1 more source
Persistent Haematuria Is Associated With Reduced Kidney Survival in Primary Podocytopathies
ABSTRACT Aim Haematuria is frequently present in podocytopathies, but its significance and prognostic value are not well described. This study aimed to determine the prevalence and association between persistent haematuria and kidney survival in patients with membranous nephropathy (MN), minimal change disease (MCD) and focal segmental ...
Gabriel Ștefan +3 more
wiley +1 more source

