Results 91 to 100 of about 306,712 (215)

Targeting panoptosis: a narrative review of its therapeutic potential in kidney disease

BMC Nephrology
Renal diseases are major global public health challenges due to their complex mechanisms and growing burden. PANoptosis, a unified programmed cell death pathway driven by the PANoptosome complex, involves the combined activation of pyroptotic, apoptotic,
Yuxin Guo, Yanru Zhao, Yanheng Qiao, Yunze Xing, Yaxuan Fang, Yuetong Zhao, Hanqi Yang, Yi Chen, Bo Yang   +8 more
doaj   +1 more source

Identifying chemokines as therapeutic targets in renal disease: Lessons from antagonist studies and knockout mice [PDF]

, 2004
Chemokines, in concert with cytokines and adhesion molecules, play multiple roles in local and systemic immune responses. In the kidney, the temporal and spatial expression of chemokines correlates with local renal damage and accumulation of chemokine ...
Abdi R, Anders HJ, Anders HJ, Anders HJ, Bruhl H, Burne-Taney MJ, Feng L, Fituri O, Fujinaka H, Garcia GE, Grone HJ, Keane MP, Mack M, Miura M, Murphy PM, Nath KA, Perez de Lema G, Rollins BJ, Romagnani P, Segerer S, Segerer S, Segerer S, Tang WW, Taub DD, Tesch GH, Tokuda A, Topham PS, Vielhauer V, Vielhauer V, Wada T, Wang Y, Wenzel U, Wu X, Wu X, Zernecke A   +34 more
core   +1 more source

Circ-0069561 as a novel diagnostic biomarker for progression of diabetic kidney disease

Renal Failure
Background Circular RNAs (circRNAs) are non-coding RNAs that are key regulators of the initiation and progression of various human diseases. However, the role of circRNAs in diabetic kidney disease (DKD) remains unknown.Methods Whole high-throughput RNA ...
Chaoyi Chen, Xinran Liu, Sai Zhu, Yukai Wang, Yu Ma, Ziyun Hu, Yonggui Wu, Ling Jiang   +7 more
doaj   +1 more source

Analgesic nephropathy [PDF]

Nephrology Dialysis Transplantation, 1996
De Broe, M. E., Elseviers, M. M., Bengtsson, U., Mihatsch, M. J., Molzahn, M., Pommer, W., Ritz, E., Schwarz, A.   +7 more
openaire   +4 more sources

Association between neutrophil-to-lymphocyte ratio and early renal function decline in patients with immunoglobulin a nephropathy

Annals of Medicine
Background IgA nephropathy (IgAN) is a chronic immune-mediated progressive kidney disease. The Neutrophil-To-Lymphocyte Ratio (NLR) has emerged as a novel marker for systemic immune inflammation.
Cun Shen, Mengchao Liu, Zhen Cai, Mengdi Wang, Lei Tian, Long Tang, Fangqiang Cui, Wenjing Zhao   +7 more
doaj   +1 more source

Development and validation of a novel nomogram model for predicting delayed graft function in deceased donor kidney transplantation based on pre-transplant biopsies

BMC Nephrology
Background Delayed graft function (DGF) is an important complication after kidney transplantation surgery. The present study aimed to develop and validate a nomogram for preoperative prediction of DGF on the basis of clinical and histological risk ...
Meihe Li, Xiaojun Hu, Yang Li, Guozhen Chen, Chen-guang Ding, Xiaohui Tian, Puxun Tian, Heli Xiang, Xiaoming Pan, Xiaoming Ding, Wujun Xue, Jin Zheng   +11 more
doaj   +1 more source

Deletion of diacylglycerol-responsive TRPC genes attenuates diabetic nephropathy by inhibiting activation of the TGFβ1 signaling pathway [PDF]

, 2017
TRPC6 plays a critical role in proteinuric kidney diseases, and TRPC3 is involved in tubulointerstitialdamage and renal fibrosis in obstructed kidneys. Podocyte loss is a characteristic event in diabetic nephropathy(DN).
Birnbaumer, Lutz, He, Xiju, Li, Shoutian, Liao, Yanhong, Liu, Benju, Xu, Benke   +5 more
core  

Effect and Safety of Finerenone in Patients with IgA Nephropathy

Journal of Inflammation Research
Yanhong Guo,* Xuewen Zhang,* Silu Zhao,* Yulin Wang, Liuwei Wang, Qiuhong Li, Lu Yu, Lin Tang Department of Nephropathy, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, People’s Republic of China ...
Guo Y, Zhang X, Zhao S, Wang Y, Wang L, Li Q, Yu L, Tang L   +7 more
doaj  

ANALGESIC NEPHROPATHY [PDF]

Australian and New Zealand Journal of Medicine, 1968
openaire   +9 more sources

The potential role of non-coding RNAs in acute kidney injury: a focus on natural medicine treatment

Frontiers in Molecular Biosciences
Acute kidney injury (AKI) is a complex clinical disease characterized by sophisticated molecular pathways. Non-coding RNAs (ncRNAs), including lncRNAs, miRNAs, and circRNAs, play a pivotal role.
Yuxin Guo, Yuxin Guo, Yanru Zhao, Yanru Zhao, Hanqing Zhang, Hanqing Zhang, Yunze Xing, Yunze Xing, Yaxuan Fang, Yaxuan Fang, Dingyuan Zheng, Dingyuan Zheng, Hanqi Yang, Hanqi Yang, Yanheng Qiao, Yanheng Qiao, Bo Yang, Bo Yang   +17 more
doaj   +1 more source