Results 71 to 80 of about 357,434 (340)

Association between change in serum uric acid and rapid decline in kidney function in China

open access: yesScientific Reports
While the elevation of serum uric acid (SUA) is acknowledged as a risk factor for chronic kidney disease, the independent extent to which variations in SUA levels are correlated with temporal changes in estimated glomerular filtration rate (eGFR) remains
Yu Li   +6 more
doaj   +1 more source

A preliminary study of KAT2A on cGAS-related immunity in inflammation amplification of systemic lupus erythematosus

open access: yesCell Death and Disease, 2021
Previous studies demonstrated that cGAS pathway is related to the inflammation amplification in a variety of autoimmune diseases. Lysine acetyltransferase family (KATs) can regulate the nuclear transcription or cytoplasmic activation of cGAS through ...
Youzhou Tang   +8 more
doaj   +1 more source

The Role of AIF-1 in the Aldosterone-Induced Vascular Calcification Related to Chronic Kidney Disease: Evidence From Mice Model and Cell Co-Culture Model

open access: yesFrontiers in Endocrinology, 2022
Increasing evidence suggests that aldosterone (Aldo) plays an essential role in vascular calcification which is a serious threat to cardiovascular disease (CVD) developed from chronic kidney disease (CKD).
Xueying Chang   +5 more
doaj   +1 more source

PROSEDUR MENANGANI KELUHAN NASABAH OLEH CUSTOMER SERVICE PADA PT. BANK RAKYAT INDONESIA (PERSERO) Tbk. UNIT SOEKARNO HATTA MALANG [PDF]

open access: yes, 2023
The task of a customer service person is to serve customers and fulfill customer desires according to the customer's requests. As the front guard, customer service is obliged to provide maximum service to customers.
Putra, Muhammad Taufik Enliana
core  

Sympathetic Activation Promotes Kidney Fibrosis in Mice via Macrophage‐Derived N2ICD‐Enriched Extracellular Vesicles

open access: yesAdvanced Science, EarlyView.
Norepinephrine/α2B‐adrenoceptor axis promotes the secretion of Notch2 intracellular domain (N2ICD)‐enriched extracellular vesicles (EVs) from macrophages. These EVs deliver N2ICD into fibroblasts, thereby inducing their activation. Deletion of Notch2 or α2B‐AR in macrophages disrupts N2ICD‐enriched EV formation and alleviates kidney fibrosis in mice ...
Huiwen Ren   +14 more
wiley   +1 more source

Nomogram for thromboembolic events in primary membranous nephropathy associated with PLA2R antibody

open access: yesScientific Reports
Patients with nephrotic syndrome, particularly those with primary membranous nephropathy (pMN), are at a heightened risk of thromboembolic events.
Zihan Zhai   +7 more
doaj   +1 more source

miR-374a Regulates Inflammatory Response in Diabetic Nephropathy by Targeting MCP-1 Expression

open access: yesFrontiers in Pharmacology, 2018
The microRNA (mir)-374a has been implicated in several types of human cancer; however, its role in diabetic nephropathy (DN) remains unclear. Monocyte chemoattractant protein (MCP)-1 is a chemokine that recruits macrophages to inflammatory sites and is ...
Zijun Yang   +7 more
doaj   +1 more source

Single‐Cell Dissection of the Biological Function and Molecular Features Underlying the Micropeptide LSMEM1 in Kidney

open access: yesAdvanced Science, EarlyView.
LSMEM1, an evolutionarily conserved micropeptide with extreme hydrophobicity (aliphatic index═113) and dynamic amphiphilicity (GRAVY═0.017), features a strong α‐helical transmembrane anchor (residues 64‐86). Single‐cell analysis reveals its critical role in renal lipid homeostasis.
Peimin Liu   +11 more
wiley   +1 more source

Pharmacological effects of raas blockade in ischemic nephropathy [PDF]

open access: yes, 2016
Background: The management of ischemic nephropathy due to atherosclerotic renal artery stenosis has become increasingly conservative in the modern era, with current guidelines recommending optimized medical therapy as the initial step.
Barbano, Biagio   +8 more
core   +1 more source

Treating Hearing Loss: From Cochlear Implantation to Gene Therapy

open access: yesAdvanced Science, EarlyView.
Cochlear implantation is the primary treatment for deafness, restoring functional hearing in over a million people. Recently, gene therapy has enabled biological hearing restoration in a small number of patients with OTOF‐related mutations. This perspective evaluates both approaches, concluding that cochlear implants will remain the standard for most ...
Fan‐Gang Zeng   +4 more
wiley   +1 more source

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