Results 81 to 90 of about 165,276 (249)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Risk of cardiac, neuropsychiatric and musculoskeletal adverse events with levothyroxine: Systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Levothyroxine (LT4) is the standard treatment for hypothyroidism and the most widely prescribed medication worldwide. Although generally safe, regulatory reports list potential cardiac, neuropsychiatric and musculoskeletal adverse events (AEs). Clarifying their clinical relevance is essential.
Bala Swetha Baskaran, Mohammad Ali Omrani, Flory T. Muanda   +2 more
wiley   +1 more source

Transfer Learning Approaches in Bioprocess Engineering: Opportunities and Challenges

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Transfer learning (TL) has recently emerged as a promising approach to overcoming one of the key limitations of bioprocess engineering: data scarcity. By leveraging knowledge from one bioprocess to another, TL allows existing models and data sets to be reused efficiently, accelerating process development, improving prediction accuracy, and ...
Daniel Barón Díaz, Anna‐Lena Drommershausen, Alexander Grünberger, Dirk Holtmann   +3 more
wiley   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

The potential role of non-coding RNAs in acute kidney injury: a focus on natural medicine treatment

Frontiers in Molecular Biosciences
Acute kidney injury (AKI) is a complex clinical disease characterized by sophisticated molecular pathways. Non-coding RNAs (ncRNAs), including lncRNAs, miRNAs, and circRNAs, play a pivotal role.
Yuxin Guo, Yuxin Guo, Yanru Zhao, Yanru Zhao, Hanqing Zhang, Hanqing Zhang, Yunze Xing, Yunze Xing, Yaxuan Fang, Yaxuan Fang, Dingyuan Zheng, Dingyuan Zheng, Hanqi Yang, Hanqi Yang, Yanheng Qiao, Yanheng Qiao, Bo Yang, Bo Yang   +17 more
doaj   +1 more source

Analgesic nephropathy [PDF]

Nephrology Dialysis Transplantation, 1996
De Broe, M. E., Elseviers, M. M., Bengtsson, U., Mihatsch, M. J., Molzahn, M., Pommer, W., Ritz, E., Schwarz, A.   +7 more
openaire   +4 more sources

Intraosseous sarcoidosis imitating peri‐implantitis: A case study

Clinical Advances in Periodontics, EarlyView.
Abstract Background Sarcoidosis is a multisystem granulomatous disorder of unknown cause, typically affecting the lungs and lymph nodes, but it can also involve the eyes, skin, heart, bones, and other organs. The exact cause is unclear, but genetic factors and environmental triggers like infections, chemicals, or dust may play a role.
Magdalena Orlowska, David S. Gottlieb, Kenneth S. Kornman   +2 more
wiley   +1 more source

Intravascular Lithotripsy Is Associated With Superior Clinical Outcomes Compared to Atherectomy: A Large‐Scale, Propensity‐Matched Analysis

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Coronary artery disease (CAD) with severe calcification remains a growing challenge in percutaneous coronary intervention (PCI). Atherectomy (ATH) has long been used for plaque modification, whereas intravascular lithotripsy (IVL) has emerged as a promising alternative. Large‐scale comparative data on long‐term outcomes are limited.
Charles D. Miks, Grant K. Ozaki, Chirayu R. Shukla, Vikram Sharma   +3 more
wiley   +1 more source

Development and validation of a novel nomogram model for predicting delayed graft function in deceased donor kidney transplantation based on pre-transplant biopsies

BMC Nephrology
Background Delayed graft function (DGF) is an important complication after kidney transplantation surgery. The present study aimed to develop and validate a nomogram for preoperative prediction of DGF on the basis of clinical and histological risk ...
Meihe Li, Xiaojun Hu, Yang Li, Guozhen Chen, Chen-guang Ding, Xiaohui Tian, Puxun Tian, Heli Xiang, Xiaoming Pan, Xiaoming Ding, Wujun Xue, Jin Zheng   +11 more
doaj   +1 more source

Association between neutrophil-to-lymphocyte ratio and early renal function decline in patients with immunoglobulin a nephropathy

Annals of Medicine
Background IgA nephropathy (IgAN) is a chronic immune-mediated progressive kidney disease. The Neutrophil-To-Lymphocyte Ratio (NLR) has emerged as a novel marker for systemic immune inflammation.
Cun Shen, Mengchao Liu, Zhen Cai, Mengdi Wang, Lei Tian, Long Tang, Fangqiang Cui, Wenjing Zhao   +7 more
doaj   +1 more source