Results 1 to 10 of about 104,728 (194)
Human kidney organoids model the tacrolimus nephrotoxicity and elucidate the role of autophagy [PDF]
The Korean Journal of Internal Medicine, 2021 Background/Aims Tacrolimus has been used as an immunosuppressive agent in organ transplantation. Despite the therapeutic benefits, tacrolimus’s use is limited due to its nephrotoxicity.
Jin Won Kim +12 more
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Sex Difference in Cisplatin-Induced Nephrotoxicity: Laboratory and Clinical Findings
Journal of Toxicology, 2022 Cisplatin (CP) as the most important anticancer drug has limited usage due to a lot of side effects such as nephrotoxicity. Additionally, nephrotoxicity is gender/sex-related.
Fatemeh Eshraghi-Jazi, Mehdi Nematbakhsh
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Asian Pacific Journal of Cancer Biology, 2022 Introduction: Head and neck cancers are the common cancers in developing countries, especially in Southeast Asia. Concurrent chemoradiation is the treatment of choice for locally advanced stage III to IVB squamous cell carcinoma of head and neck ...
Mahfujul Ahmed Riad
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International Journal of Bipolar Disorders, 2015 AbstractReports of toxic effects on the kidney of lithium treatment emerged very soon after lithium therapy was introduced. Lithium-induced nephrogenic diabetes insipidus is usually self-limiting or not clinically dangerous. Some reports of irreversible chronic kidney disease and renal failure were difficult to attribute to lithium treatment since ...
Azab, Abed N. +5 more
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Molecular Therapy: Nucleic Acids, 2023 Billions of people worldwide have experienced irreversible kidney injuries, which is mainly attributed to the complexity of drug-induced nephrotoxicity.
Kexing Xi +5 more
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Frontiers in Pharmacology, 2020 AimAntineoplastic effect of cisplatin, the first line treatment in non-small cell lung cancer (NSCLC), is hindered by its nephrotoxicity and myelotoxicity. Both low-dose and high-dose regimens are used in the management of NSCLC. The aim of this study is
Zulfan Zazuli +9 more
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Atazanavir nephrotoxicity [PDF]
Clinical Kidney Journal, 2015 Atazanavir is commonly used as one of the key drugs in combination antiretroviral therapy for human immunodeficiency virus (HIV). However, atazanavir has the potential to yield its crystalline precipitation in urine and renal interstitial tissues, leading to crystalluria, urolithiasis, acute kidney injury (AKI) or chronic kidney disease (CKD).
Hara, Masaki +5 more
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Bibliometric and visual analysis of nephrotoxicity research worldwide
Frontiers in Pharmacology, 2022 Background: Nephrotoxicity of drugs contributes to acute kidney injury with high mortality and morbidity, which crucially limits the application and development of drugs.
Tianmu He +9 more
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Inhibition of gentamicin–induced renal tubular cell necrosis [PDF]
Journal of Nephropathology, 2012 Gentamicin nephrotoxicity limit its usage against gram negative bacteria. Most researches showed that antioxidant agents improved gentamicin nephrotoxicity.
Majid Tavafi
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F1000Research, 2017 Nephrotoxic medication exposure is nearly ubiquitous in hospitalized patients and represents one of the most common causes of acute kidney injury (AKI) in the hospitalized setting. Although provision of medications that are nephrotoxic has led to improved outcomes in terms of treatment of underlying illness, unnecessary nephrotoxic medication exposure ...
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