Results 111 to 120 of about 121,280 (344)

Risk factors for calcineurin inhibitor nephrotoxicity after renal transplantation: a systematic review and meta-analysis

Drug Design, Development and Therapy, 2018
Tianyi Xia, Sang Zhu, Yan Wen, Shouhong Gao, Mingming Li, Xia Tao, Feng Zhang, Wansheng Chen Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai, People’s Republic of China Background: Nephrotoxicity of ...
Xia T, Zhu S, Wen Y, Gao S, Li M, Tao X, Zhang F, Chen W   +7 more
doaj  

Use of phytotherapics in dogs and cats. [PDF]

, 2008
Phytotherapy is one of the most utilized non conventional medicines (NCM) both in human and veterinary medicine. It can be used to mitigate and prevent slight diseases and to support conventional medicine using allopathic drugs. In this paper the Authors
AUTORE G., DE TOMMASI N., MARZOCCO S., RUSSO, ROSARIO, SEVERINO, LORELLA   +4 more
core  

Pharmacokinetics of dolutegravir, tenofovir and lamivudine during venous–venous extracorporeal membrane oxygenation (VV‐ECMO): A case report

British Journal of Clinical Pharmacology, EarlyView.
While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart, Emiel Leegwater, Thomas H. Ottens, Emile F. Schippers, Erik B. Wilms, David M. Burger, Cees van Nieuwkoop, Liesbeth B. E. Bosma   +7 more
wiley   +1 more source

Is It Still Beneficial to Monitor the Trough Concentration of Vancomycin? A Quantitative Meta-Analysis of Nephrotoxicity and Efficacy

Antibiotics
This study conducted a quantitative meta-analysis to investigate the association of vancomycin indicators, particularly area under the curve over 24 h (AUC24) and trough concentrations (Ctrough), and their relationship with both nephrotoxicity and ...
Wanqiu Yang, Kaiting Zhang, Yuancheng Chen, Yaxin Fan, Jing Zhang   +4 more
doaj   +1 more source

Effect of FK506 in experimental organ transplantation. [PDF]

, 1988
FK506 is the most potent immunosuppressive agent known. Its toxicity is substantial in dogs, minor in rats, and unknown in subhuman primates. In small doses that are nontoxic even in dogs, it can be used in synergistic combination with cyclosporine ...
Casavilla, A., ChapChap, P., Demetris, J., Imventarza, O., Kahn, D., Makowka, L., Murase, N., Okuda, K., Podesta, L., Starzl, T.E., Todo, S., Ueda, Y.   +11 more
core  

Tacrolimus exposure during pregnancy in kidney and liver transplantation recipients: A comparison between whole blood and plasma concentration‐to‐dose ratios

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus monitoring is generally performed in whole blood (WB). Most (>85%) of circulating tacrolimus is bound to red blood cells. During pregnancy, WB monitoring might be suboptimal because of physiological changes including increased plasma volume and decreased haematocrit.
Jildau R. Meinderts, Paola Mian, Frederike G. I. van Vilsteren, Karien M. H. van de Wetering, Jelmer R. Prins, Stefan P. Berger, Daan J. Touw, Margriet F. C. de Jong   +7 more
wiley   +1 more source

Comprehensive Assessment of Colistin Induced Nephrotoxicity: Incidence, Risk Factors and Time Course

Infection and Drug Resistance, 2023
Razan Rabi,1,* Ahmad Enaya,1,* Mamoun W Sweileh,1 Banan M Aiesh,2 Ashraqat Namrouti,1 Zakaria I Hamdan,1,3 Dina Abugaber,1,3 Zaher Nazzal3 1Department of Internal Medicine, An-Najah National University Hospital, Nablus, Palestine; 2Infection ...
Rabi R, Enaya A, Sweileh MW, Aiesh BM, Namrouti A, Hamdan ZI, Abugaber D, Nazzal Z   +7 more
doaj  

Intestinal transplantation [PDF]

, 1994
Intestinal transplantation is often the only alternative form of treatment for patients dependent on total parenteral nutrition for survival.
Andreas G. Tzakis, M.D, Deltz E, Murase N, Satoru Todo, M.D, Starzl TE, Starzl TE, Starzl TE, Thomas E. Starzl, M.D., Ph.D, Todo S, Tzakis AG   +9 more
core   +1 more source

Theranostic nanoplatform for high‐performance dual‐modal magnetic resonance imaging‐guided therapy of orthotopic hepatocellular carcinoma

BMEMat, EarlyView.
This article introduces a biomimetic Mn‐doped polydopamine nanoplatform (HAMM NPs) coated with cancer cell membranes. It enables targeted hepatocellular carcinoma theranostics via T1/T2 dual‐mode magnetic resonance imaging and tumor microenvironment‐triggered sonodynamic therapy/chemodynamic therapy, achieving potent antitumor efficacy in subcutaneous ...
Jiayin Lin, Wenbo Chen, Xiuqi Hou, Kai Wang, Fan Liu, Ruling Zhang, Zhong Cao, Jian Zheng   +7 more
wiley   +1 more source

Nano‐networks via reaction‐induced self‐assembly coordinate spatiotemporal multi‐drug delivery for acute kidney injury therapy

BMEMat, EarlyView.
Multifunctional nano‐networks (NNWs) are prepared via reaction‐induced self‐assembly (RISA) of spermidine (SPD), epigallocatechin gallate (EGCG), 2‐formylphenylboronic acid (2‐FPBA), and deferoxamine (DFO) through dynamic iminoboronate bonds. These NNWs leverage the oxidative AKI microenvironment to trigger disintegration, enabling site‐specific ...
Juan Jin, Xiao Zhang, Chenxi Wang, Taian Jin, Xinyang Fang, Yixuan Gao, Mengchun Chen, Weiyang Meng, Chang Gao, Wenlu Li, Yuanfeng Li, Yijie Chen, Calvin A. Omolo, Thirumala Govender, Linqi Shi, Yunguang Wang, Yong Liu, Qiang He   +17 more
wiley   +1 more source