Results 121 to 130 of about 72,055 (308)

Is It Still Beneficial to Monitor the Trough Concentration of Vancomycin? A Quantitative Meta-Analysis of Nephrotoxicity and Efficacy

Antibiotics
This study conducted a quantitative meta-analysis to investigate the association of vancomycin indicators, particularly area under the curve over 24 h (AUC24) and trough concentrations (Ctrough), and their relationship with both nephrotoxicity and ...
Wanqiu Yang, Kaiting Zhang, Yuancheng Chen, Yaxin Fan, Jing Zhang   +4 more
doaj   +1 more source

Glycopolymeric nanoparticles transported by activated platelets protect ischemic myocardium by alleviating PANoptosis through targeting macrophage Dectin‐1

BMEMat, EarlyView.
NP‐SF, designed to target macrophage Dectin‐1 and activated platelets, selectively accumulated in ischemic myocardium, where it was taken up by macrophages after platelet hitchhiking. By inhibiting NLRC5‐related PANoptosis, NP‐SF significantly attenuated pathological damage, and effectively preserved cardiac function in a murine ischemia–reperfusion ...
Guanye Yu, Na Yang, Yan Zhang, Lingxin Peng, Yi Li, Yue Chao, Qinfang Miao, Haikun Qi, Jianhui Zhuang, Weixia Jian, Bingyu Li, Wenhui Peng, Jinghua Chen, Shiyu Gong   +13 more
wiley   +1 more source

Drug-induced nephrotoxicity [PDF]

, 2017
Drug-induced nephrotoxicity is an extremely common condition and is responsible for a variety of pathological effects on the kidneys. Drug-induced acute renal failure (ARF) accounted for 20% of all ARF cases.
Pathak, Deepanjali, Dhodi, Dinesh K., Patel, Sadiq B., Bhagat, Sagar B.   +3 more
core   +1 more source

An all‐in‐one fucosylated gold nanocluster probe enables NIR‐II imaging and multi‐mechanistic therapy of acute kidney injury

BMEMat, EarlyView.
This study developed a fucoside‐targeted gold nanocluster probe that enables early NIR‐II imaging and multi‐mechanistic therapy for acute kidney injury, effectively mitigating oxidative stress, modulating inflammatory responses, and inhibiting ferroptosis to improve renal outcomes. Abstract Acute kidney injury (AKI) remains a life‐threatening condition
Ping Zhang, Boning Tan, Suqing Feng, Beibei Gu, Ting Feng, Haiguang Zhu, Jianping Xie, Xun Yuan   +7 more
wiley   +1 more source

Maximizing Neurovascular Outcomes of Facial Transplantation: A Comprehensive Review

Clinical Anatomy, EarlyView.
ABSTRACT Facial transplantation is a division of reconstructive surgery which aims to improve the function and appearance of a face that has endured severe disfigurement. Currently, the face transplant procedure uses allogenic tissue, harvested from a brain‐dead donor, to replace damaged facial components.
Olivia A. James, Faye Bennett
wiley   +1 more source

Comprehensive Assessment of Colistin Induced Nephrotoxicity: Incidence, Risk Factors and Time Course

Infection and Drug Resistance, 2023
Razan Rabi,1,* Ahmad Enaya,1,* Mamoun W Sweileh,1 Banan M Aiesh,2 Ashraqat Namrouti,1 Zakaria I Hamdan,1,3 Dina Abugaber,1,3 Zaher Nazzal3 1Department of Internal Medicine, An-Najah National University Hospital, Nablus, Palestine; 2Infection ...
Rabi R, Enaya A, Sweileh MW, Aiesh BM, Namrouti A, Hamdan ZI, Abugaber D, Nazzal Z   +7 more
doaj  

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, EarlyView.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Nephrotoxicity of halogenated inhalational anaesthetics: Fictions and facts [PDF]

, 2002
Reichle, Florian M., Peter, Klaus, Conzen, Peter F.   +2 more
core   +1 more source

A review of Tenofovir Disoproxil Fumarate associated nephrotoxicity among People Living with HIV: Burden, risk factors and solutions

Clinical Epidemiology and Global Health
Background: Tenofovir Disoproxil Fumarate (TDF) is one of the first-line antiretroviral therapy (ART) recommended for all treatment naïve People Living with HIV (PLHIV). However, evidence indicates increasing TDF-associated nephrotoxicity among PLHIV due
Edwin Sam Asirvatham, Varsha Ranjan, Chhavi Garg, Charishma Jones Sarman, Mahalingam Periasamy, Vijay Yeldandi, Sunita Upadhyaya, Bhawna Rao   +7 more
doaj   +1 more source