Results 111 to 120 of about 63,588 (218)

Managing the meniscus part I—Anatomy, biomechanics, and treatment strategies for the atraumatic meniscus tear

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose The purpose of this article is to serve as the first of a two‐part review on the meniscus; in this review, we will establish the background on anatomy and pathogenesis of the meniscus, as well as the effect of the meniscus on native knee kinematics and function.
Ehab M. Nazzal, Jonathan D. Hughes, Armin Runer, Matthew P. Kolevar, Jorge Chahla, Robert G. Marx, James J. Irrgang, Roman Seil, Berte Bøe, David Parker, Ryosuke Kuroda, Eric H. Senorski, Sachin Tapasvi, Volker Musahl   +13 more
wiley   +1 more source

Weight-based polymyxin B dosing for mortality and nephrotoxicity: an exploratory dose-response study. [PDF]

J Antimicrob Chemother
Pan SC, Tsai MT, Wang JT, Sheng WH, Chuang YC.   +4 more
europepmc   +1 more source

Trough concentrations of 10-15 mg/L of vancomycin are generally sufficient to achieve pharmacodynamic targets, whereas higher troughs can result in unnecessary nephrotoxicity: we respectfully disagree. [PDF]

Crit Care
Honoré PM, Benkaddour Y, Muscato CY.
europepmc   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Hesperidin Attenuates Vincristine-Induced Nephrotoxicity via Nrf2/HO-1 and PI3K/Akt/mTOR Signaling. [PDF]

J Biochem Mol Toxicol
Genc A, Akoglan B, Sahin E, Cankaya E.
europepmc   +1 more source

Targeted Muscle Reinnervation for Intuitive Prosthetic Control

Muscle &Nerve, EarlyView.
ABSTRACT The convergence of medical and technological advances has led to a substantial expansion of therapeutic approaches for patients with limb amputations. Targeted muscle reinnervation (TMR) is one of the strategies to improve control of bionic arms and has been applied for more than two decades. Through surgical rewiring of the nerves responsible
Nitay Maile, Laura Ferrante, Dario Farina, Ulla Al Dabbass, Oskar C. Aszmann, Vlad Tereshenko   +5 more
wiley   +1 more source

Toxoplasma gondii Infection After Kidney Transplantation: A Case Report and Literature Review

Organ Medicine, EarlyView.
Toxoplasma gondii infection after kidney transplantation is rare and presents with nonspecific clinical manifestations; however, the associated mortality rate is high. We discuss the relevant literature, clinical manifestations, therapeutic regimens, and prognoses of post‐transplantation toxoplasmosis.
Peng Zhang, Xingqiang Lai, Rongxin Chen, Li Li, Jiali Fang, Guanghui Li, Junjie Ma, Luhao Liu, Zheng Chen   +8 more
wiley   +1 more source

RETRACTED: Das et al. Carnosic Acid Attenuates Cadmium Induced Nephrotoxicity by Inhibiting Oxidative Stress, Promoting Nrf2/HO-1 Signalling and Impairing TGF-β1/Smad/Collagen IV Signalling. <i>Molecules</i> 2019, <i>24</i>, 4176. [PDF]

Molecules
Das S, Dewanjee S, Dua TK, Joardar S, Chakraborty P, Bhowmick S, Saha A, Bhattacharjee S, De Feo V.   +8 more
europepmc   +1 more source

Aspartic Protease Inhibition Induces Proteomic Remodeling in Paracoccidioides brasiliensis

PROTEOMICS, EarlyView.
ABSTRACT Paracoccidioidomycosis (PCM) is a major systemic mycosis in Latin America caused by Paracoccidioides brasiliensis, yet the contribution of aspartic proteases to fungal physiology and pathogenicity remains poorly understood. Here, we employed data‐independent acquisition (DIA)‐based quantitative proteomics to investigate the impact of pepstatin
Sarah Fernandes Lima, Wilson Dias Segura, Leonardo Brogliato de Moraes, Reinaldo Souza Oliveira, Pedro Henrique Corteletti Manfio, Alison Felipe Alencar Chaves, Wagner Luiz Batista   +6 more
wiley   +1 more source

Redox biology underlying the efficacy and toxicity of colistin as a last-resort antibiotic. [PDF]

Front Microbiol
Soria-Herrera RJ, Trujillo-Rangel WÁ, García-Benavides L, Diaz-De la Cruz EN.   +3 more
europepmc   +1 more source