Results 21 to 30 of about 16,895 (259)
Dynamic Changes in Pentraxin-3 and Neprilysin in ST Segment Elevation Myocardial Infarction
Biomedicines, 2022 Pentraxin-3 (PTX3) and neprilysin have been associated with increased morbidity and mortality in chronic inflammatory disease and heart failure, but these biomarkers have been studied less in patients with ST segment elevation myocardial infarction ...
Rahel Befekadu +4 more
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Angiotensin receptor blocker neprilysin inhibitors
World Journal of Cardiology, 2021 Heart failure (HF) is a clinical syndrome that results from a structural or functional cardiac disorder that reduces the ability of the ventricle of the heart to fill with, or eject, blood. It is a multifaceted clinical condition that affects up to 2% of the population in the developed world, and is linked to significant morbidity and mortality; it is ...
Usuda, Daisuke +18 more
openaire +2 more sources
Autocrine regulation of human sperm motility by tachykinins
Reproductive Biology and Endocrinology, 2010 Background We examined the presence and function of tachykinins and the tachykinin-degrading enzymes neprilysin (NEP) and neprilysin-2 (NEP2) in human spermatozoa.
Pinto Francisco M +7 more
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Association between soluble neprilysin and diabetes: Findings from a prospective longitudinal study
Frontiers in Endocrinology, 2023 BackgroundThe potential role of neprilysin (NEP) in glucose metabolism has been found by basic studies but lacks population evidence. The objective of this study was to examine the association between serum NEP and diabetes in Chinese adults.MethodsIn a ...
Junting Hu +10 more
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Potential of valsartan+sacubitril therapy in hypertensive heart disease
Российский кардиологический журнал, 2021 The course of hypertension is often complicated by left ventricular hypertrophy (or hypertensive heart disease, HHD). The main “corridor” of natural HHD is development of heart failure with preserved ejection fraction (HFpEF).
A. G. Ovchinnikov +4 more
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Frontiers in Physiology, 2018 Chronic hypoxia has been postulated as one of the mechanisms involved in salt-sensitive hypertension and chronic kidney disease (CKD). Kidneys have a critical role in the regulation of arterial blood pressure through vasoactive systems, such as the renin-
Carlos P. Vio +8 more
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Changes in Aβ42, Neprilysin, and γ-Secretase in the Hippocampus of Male Rats Alzheimer’s model: The Effects of Aerobic Training and Omega-3 Intake [PDF]
Journal of Kerman University of Medical Sciences, 2023 Background: Alzheimer›s disease (AD) is characterized by excessive deposition of the amyloid-β peptide (Aβ) in the central nervous system and reducing its level is the goal of many medications.
Ali Yaghoubi
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Roles of Natriuretic Peptides and the Significance of Neprilysin in Cardiovascular Diseases
Biology, 2022 Atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) activate the guanylyl cyclase A receptor (GC-A), which synthesizes the second messenger cGMP in a wide variety of tissues and cells.
Hitoshi Nakagawa, Yoshihiko Saito
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microPublication biology, 2021 The neprilysin (M13) family of metalloendopeptidases comprises highly conserved ectoenzymes that cleave and thereby inactivate many physiologically relevant peptides in the extracellular space. Impaired neprilysin activity is associated with numerous human diseases.
Meyer, Heiko +5 more
openaire +3 more sources
Brazilian Journal of Medical and Biological Research, 1997 Two intramolecularly quenched fluorogenic peptides containing o-aminobenzoyl (Abz) and ethylenediamine 2,4-dinitrophenyl (EDDnp) groups at amino- and carboxyl-terminal amino acid residues, Abz-DArg-Arg-Leu-EDDnp (Abz-DRRL-EDDnp) and Abz-DArg-Arg-Phe ...
M.A.S. Medeiros +4 more
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