Results 91 to 100 of about 4,230,808 (299)
A model of toxic neuropathy in Drosophila reveals a role for MORN4 in promoting axonal degeneration [PDF]
, 2012 Axonal degeneration is a molecular self-destruction cascade initiated following traumatic, toxic, and metabolic insults. Its mechanism underlies a number of disorders including hereditary and diabetic neuropathies and the neurotoxic side effects of ...
Bhattacharya, Martha R.C. +7 more
core +2 more sources
Pain relief for women with cervical intraepithelial neoplasia undergoing colposcopy treatment [PDF]
, 2012 Treatment for CIN is usually undertaken in an outpatient colposcopy clinic to remove the pre-cancerous cells from the cervix. It commonly involves lifting the cells off the cervix with electrically heated wire (diathermy) or laser, or destroying the ...
AI-Kurdi +31 more
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, 2023 Nerve agents, are organic chemicals that interrupt the cholinergic transmission to organs by irreversible inhibition of enzyme acetylcholinesterase.(1) This leads to the accumulation of neurotransmitter acetylcholine (ACh), which can ultimately lead to fatality.
openaire +1 more source
Organophosphate Nerve Agent Detection with Europium Complexes
The Scientific World Journal, 2004 We explore the detection of paraoxon, a model compound for nonvolatile organophosphate nerve agents such as VX. The detection utilizes europium complexes with 1,10 phenanthroline and thenoyltrifluoroacetone as sensitizing ligands.
Jake R. Schwierking +2 more
doaj +1 more source
Tuning Butyrylcholinesterase Inactivation and Reactivation by Polymer‐Based Protein Engineering
Advanced Science, 2020 Organophosphate nerve agents rapidly inhibit cholinesterases thereby destroying the ability to sustain life. Strong nucleophiles, such as oximes, have been used as therapeutic reactivators of cholinesterase‐organophosphate complexes, but suffer from ...
Libin Zhang +7 more
doaj +1 more source
A Review Article on Nerve Agents
Hong Kong Journal of Emergency Medicine, 2002 The incidence of Tokyo subway attack by the Aum Shinrikyo cult in 1995 had raised the concern of the use of nerve agent as a weapon in terrorist attack. The recent event in World Trade Centre in New York city had further brought our attention to the possibility of terrorist attacks using these agents.
Syh Tang, Jts Chan
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Local administration of icariin contributes to peripheral nerve regeneration and functional recovery
Neural Regeneration Research, 2015 Our previous study showed that systemic administration of the traditional Chinese medicine Epimedium extract promotes peripheral nerve regeneration. Here, we sought to explore the therapeutic effects of local administration of icariin, a major component ...
Bo Chen +9 more
doaj +1 more source
Cyclosarin-An Organophosphate Nerve Agent
Defence Science Journal, 2005 Organophosphorus compounds ascribed to as nerve agents (sarin, soman, tabun, cyclosarin) are highly toxic, and are considered to be the most dangerous chemical compounds. All apparently share a common mechanism of cholinesterase inhibition and can cause similar svmotoms. The . .
Gabriela Krejčová +2 more
openaire +2 more sources
Protein engineering, design & selection : PEDS, 2017 Improving an enzyme's initially low catalytic efficiency with a new target substrate by an order of magnitude or two may require only a few rounds of mutagenesis and screening or selection.
M. Goldsmith +11 more
semanticscholar +1 more source
BioengineeringPeripheral nerve injuries are a significant concern in surgical procedures, often leading to chronic pain and functional impairment. Despite advancements in imaging, preoperative and intraoperative visualization of peripheral nerves remains a challenge ...
Rui Tang +4 more
doaj +1 more source