Results 81 to 90 of about 1,688,218 (301)
Frontiers in Medicine, 2020 Introduction: Current imaging modalities for peripheral nerves display the nerve's structure but not its function. Based on a nerve's capacity for axonal transport, it may be visualized by targeted application of a contrast agent and assessing the ...
Vlad Tereshenko +23 more
doaj +1 more source
Neutral 1,3-Diindolylureas for nerve agent remediation
, 2012 Efficient neutralization of nerve?agent simulants by 1,3?diindolylureas in a neutral medium was investigated (see scheme; DCP=diethylchlorophosphate, DCNP=diethylcyanophosphonate).
Costero Nieto, Ana María +18 more
core +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Nerve-terminal and Schwann-cell response after nerve injury in the absence of nitric oxide
, 2015 Dystrophic muscles show alterations in the dystrophin-glycoprotein complex and a lack of neuronal nitric oxide (NO) synthase. In mdx mice, presynaptic expression of neuronal NO synthase is decreased, suggesting that presynaptic signaling may be altered ...
Santo, H +3 more
core +2 more sources
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Investigation into the pharmacodynamics of ethanol as a nerve blocking agent
, 2014 Ethanol is a known nerve-blocking agent, yet its clinical use is minimal. This is partly due to unclear dosage levels and not enough knowledge of its pharmacodynamics and overwhelming dominance of its psychomotor properties.
Maibvise, Charles
core
Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora
FEBS Open Bio, EarlyView.This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi +6 more
wiley +1 more source
SAW Chemical Array Device Coated with Polymeric Sensing Materials for the Detection of Nerve Agents
Sensors, 2020 G nerve agents are colorless, odorless, and lethal chemical warfare agents (CWAs). The threat of CWAs, which cause critical damage to humans, continues to exist, e.g., in warfare or terrorist attacks. Therefore, it is important to be able to detect these
Jinuk Kim +4 more
doaj +1 more source
Investigation into the pharmacodynamics of ethanol as a nerve blocking agent
, 2019 Ethanol is a known nerve-blocking agent, yet its clinical use is minimal. This is partly due to unclear dosage levels and not enough knowledge of its pharmacodynamics and overwhelming dominance of its psychomotor properties.
Maibvise, Charles
core
High-throughput screening of solid-state catalysts for nerve agent degradation
, 2018 A high-throughput screening (HTS) method was devised to increase the rate of discovery and evaluation of nerve agent degradation catalysts.
Gregory W. Peterson +6 more
core +1 more source