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Organophosphate nerve agents

Handbook of Toxicology of Chemical Warfare Agents, 2020
Publisher Summary The chemical warfare (CW) nerve agents primarily addressed in this chapter include the anticholinesterase nerve agents tabun (GA), sarin (GB), soman (GD), cyclosarin (GF), and VX, all of which are, or have been, part of the US domestic munitions inventories. These agents are potent anticholinesterase compounds deliberately formulated
A. Watson   +5 more
semanticscholar   +3 more sources

Environmental exposure to organophosphorus nerve agents.

Environmental Toxicology and Pharmacology, 2017
Exposure to organophosphorus nerve agents, the most deadly chemical warfare agents, is possible in a variety of situations, such as destruction of chemical warfare agents, terrorist attacks, armed conflicts or accidents in research laboratories and storage facilities.
S. Vučinić   +9 more
semanticscholar   +7 more sources

Effective Degradation of Novichok Nerve Agents by the Zirconium Metal-Organic Framework MOF-808.

ACS Applied Materials and Interfaces, 2022
Novichoks are a novel class of nerve agents (also referred to as the A-series) that were employed in several poisonings over the last few years. This calls for the development of novel countermeasures that can be applied in protective concepts (e.g ...
M. D. de Koning   +4 more
semanticscholar   +1 more source

Paper-Based Analytical Device for the On-Site Detection of Nerve Agents.

ACS Applied Bio Materials, 2021
We report a colorimetric paper-based microfluidic device based on an enzyme inhibition assay that allows the on-site detection of nerve agents by sampling and wicking.
Akinori Yamaguchi   +3 more
semanticscholar   +1 more source

Zirconium-Based Metal-Organic Frameworks for the Catalytic Hydrolysis of Organophosphorus Nerve Agents.

ACS Applied Materials and Interfaces, 2020
Organophoshorus nerve agents are among the most toxic chemicals known to humans, and because of their unfortunate recent use despite international bans, there is an urgent need to develop materials that can effectively degrade these nerve agents.
Kent O. Kirlikovali   +4 more
semanticscholar   +1 more source

Nerve agents

Neurology, 1992
Nerve agents produce neuromuscular blockade and convulsions in exposed humans. Military personnel in areas of potential exposure take prophylactic pyridostigmine. They are instructed to self-administer atropine and pralidoxime at the first sign of nerve agent toxicity.
Carl H. Gunderson   +3 more
openaire   +3 more sources

Sensitive Untargeted Screening of Nerve Agents and Their Degradation Products Using Liquid Chromatography-High Resolution Mass Spectrometry.

Analytical Chemistry, 2020
Nerve agents (NAs) are notorious chemical warfare agents that pose a serious threat to national security and public health. The total number of theoretical chemicals of NAs and their degradation products (DPs) exceeds 410,000, according to 1.A.01-1.A.03 ...
M. Zhang   +13 more
semanticscholar   +1 more source

High-Throughput Screening of MOFs for Breakdown of V-Series Nerve Agents.

ACS Applied Materials and Interfaces, 2020
Metal-organic frameworks (MOFs) have shown promise for the catalytic decomposition of chemical weapons. Finding the best materials for the degradation of nerve agents requires the ability to screen a high number of samples and elucidate the key ...
Joseph M Palomba   +6 more
semanticscholar   +1 more source

How to defeat a nerve agent [PDF]

open access: possibleScience, 2018
Urgent efforts are underway to find better countermeasures to the potent chemical weapons.
openaire   +2 more sources

Integration of Metal-Organic Frameworks on Protective Layers for Destruction of Nerve Agents under Relevant Conditions.

Journal of the American Chemical Society, 2019
Metal-organic frameworks (MOFs) are promising candidates for the catalytic hydrolysis of nerve agents and their simulants. Though highly efficient, bulk water and volatile bases are often required for hydrolysis with these MOF catalysts, preventing real ...
Zhijie Chen   +10 more
semanticscholar   +1 more source

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