Results 1 to 10 of about 1,609,891 (295)

Tuning Butyrylcholinesterase Inactivation and Reactivation by Polymer‐Based Protein Engineering

Advanced Science, 2020
Organophosphate nerve agents rapidly inhibit cholinesterases thereby destroying the ability to sustain life. Strong nucleophiles, such as oximes, have been used as therapeutic reactivators of cholinesterase‐organophosphate complexes, but suffer from ...
Libin Zhang, Stefanie L. Baker, Hironobu Murata, Nicholas Harris, Weihang Ji, Gabriel Amitai, Krzysztof Matyjaszewski, Alan J. Russell   +7 more
doaj   +1 more source

Smart Sensing of Nerve Agents

ChemPlusChem
AbstractThe recent international scenario highlights the importance to protect human health and environmental quality from toxic compounds. In this context, organophosphorous (OP) Nerve Agents (NAs) have received particular attention, due to their use in terrorist attacks.
Puglisi, Roberta, Santonocito, Rossella, Pappalardo, Andrea, Trusso Sfrazzetto, Giuseppe   +3 more
openaire   +3 more sources

Local administration of icariin contributes to peripheral nerve regeneration and functional recovery

Neural Regeneration Research, 2015
Our previous study showed that systemic administration of the traditional Chinese medicine Epimedium extract promotes peripheral nerve regeneration. Here, we sought to explore the therapeutic effects of local administration of icariin, a major component ...
Bo Chen, Su-ping Niu, Zhi-yong Wang, Zhen-wei Wang, Jiu-xu Deng, Pei-xun Zhang, Xiao-feng Yin, Na Han, Yu-hui Kou, Bao-guo Jiang   +9 more
doaj   +1 more source

4‐Aminopyridine promotes functional recovery and remyelination in acute peripheral nerve injury

EMBO Molecular Medicine, 2016
Traumatic peripheral nerve damage is a major medical problem without effective treatment options. In repurposing studies on 4‐aminopyridine (4‐AP), a potassium channel blocker that provides symptomatic relief in some chronic neurological afflictions, we ...
Kuang‐Ching Tseng, Haiyan Li, Andrew Clark, Leigh Sundem, Michael Zuscik, Mark Noble, John Elfar   +6 more
doaj   +1 more source

Invasion of Calcium Hydroxide Preparations Leading to Severe Chemical Nerve Injury Treated Through Nerve Repair Using Artificial Nerve Conduit: A Case Report

Case Reports in Dentistry
Calcium hydroxide is an effective agent in endodontic treatment worldwide. Some cases reported that treating a mandibular molar can lead to severe incidents of overfilling from the root canal, which leads to nerve disturbance. However, it remains unclear
Akihiro Nishiyama, Andreas Neff, Takahiro Nakada, Takaharu Ariizumi, Akira Iwasaki, Keisuke Sugahara, Akira Katakura   +6 more
doaj   +1 more source

Supramolecular Detection of a Sub-ppm Nerve Agent Simulant by a Smartphone Tool. [PDF]

ACS Omega, 2023
Puglisi R, Santonocito R, Butera E, Mendola GL, Pappalardo A, Trusso Sfrazzetto G.   +5 more
europepmc   +1 more source

Nerve Agents [PDF]

Journal of the Royal Army Medical Corps, 2002
openaire   +1 more source

Impact of Solvent Choice on SERS Sensing: Solvent-Analyte and Solvent-Substrate Effects for Organophosphate and Nerve Agent Detection. [PDF]

J Phys Chem A
Öberg R, Segervald J, Larsson A, Andersson M, Andersson PO.   +4 more
europepmc   +1 more source

COF-supported zirconium oxyhydroxide as a versatile heterogeneous catalyst for Knoevenagel condensation and nerve agent hydrolysis. [PDF]

iScience, 2023
Shekhar P, Datta Devulapalli VS, Reji R, Singh HD, Jose A, Singh P, Torris A, Vinod CP, Tokarz JA, Mahle JJ, Peterson GW, Borguet E, Vaidhyanathan R.   +12 more
europepmc   +1 more source

Evidence of nerve agent VX exposure in rat plasma by detection of albumin-adducts in vitro and in vivo. [PDF]

Arch Toxicol, 2023
Kranawetvogl T, Kranawetvogl A, Scheidegger L, Wille T, Steinritz D, Worek F, Thiermann H, John H.   +7 more
europepmc   +1 more source