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Nerve agents (NAs) induce a severe cholinergic crisis that can lead to status epilepticus (SE). Current guidelines for treatment of NA-induced SE only include prehospital benzodiazepines, which may not fully resolve this life-threatening condition.
Julia E. Morgan +11 more
doaj +1 more source
Release of vasopressin from isolated permeabilized neurosecretory nerve terminals is blocked by the light chain of botulinum A toxin [PDF]
The intracellular action on exocytosis of botulinim A toxin and constituent chains was studied using permeabilized isolated nerve endings from the rat neural lobe. The release of the neuropeptide vasopressin was measured by radioimmunoassay.
Dayanithi, G. +4 more
core +6 more sources
Nerve agents: emergency preparedness [PDF]
Nerve agents (NAs) are a highly toxic group of chemical warfare agents. NAs are organophosphorus esters with varying physical and chemical properties depending on the individual agent. The most recently developed class of NA is‘Novichok’, the existence of which was first revealed in the early 1990s, just before Russia signed the Chemical Weapons ...
Alan George Andrew Weir +2 more
openaire +2 more sources
The catalytic performances of the catalysts and decomposition mechanisms of dimethyl methylphosphonate (DMMP), a commonly used nerve agent simulant, are well understood based on previous studies.
Weimin Kong +6 more
doaj +1 more source
Objective Exposure to the nerve agent, soman (GD), induces status epilepticus (SE), epileptogenesis, and even death. Although rodent models studying the pathophysiological mechanisms show females to be more reactive to soman, no tangible sex differences ...
Meghan Gage +6 more
doaj +1 more source
Theoretical study on the toxicity of ‘Novichok’ agent candidates [PDF]
The identities and properties of ‘Novichok’ (Russian for ‘newcomer’ or ‘novice’) agents allegedly used in the recent terrorist attack in the UK have not been well documented. Although several people previously involved in the synthesis of these materials
Keunhong Jeong, Junwon Choi
doaj +1 more source
Composites of metal-organic frameworks and carbon materials have been suggested to be effective materials for the decomposition of chemical warfare agents.
Jaeheon Lee +5 more
doaj +1 more source
Social media video analysis methodology for sarin exposure
As social media becomes increasingly ubiquitous, many events are recorded and released on social media platforms, including chemical weapon attacks.
Sadik Toprak +5 more
doaj +1 more source
Theoretical study of the molecular aspect of the suspected novichok agent A234 of the Skripal poisoning [PDF]
Novichoks are the suspected nerve agents in the March 2018 Skripal poisoning. In this context, the novichok agent A234 (chemical structure proposed by Mirzayanov) was studied using computational methods to shed light on its molecular, electronic ...
Hanusha Bhakhoa +2 more
doaj +1 more source
Ethanol Ablation of a Peripheral Nerve Sheath Tumor Presenting as a Small Bowel Obstruction. [PDF]
Ethanol has historically been used as an ablative agent for a variety of lesions. One of the more common applications of this technique is celiac plexus neurolysis; however, recent reports have suggested a role for the endoscopic alcohol ablation of a ...
Chang, Kenneth +4 more
core +1 more source

