Results 11 to 20 of about 1,688,218 (301)

Biphasic response of human iPSC-derived neural network activity following exposure to a sarin-surrogate nerve agent [PDF]

Frontiers in Cellular Neuroscience
Organophosphorus nerve agents (OPNA) are hazardous environmental exposures to the civilian population and have been historically weaponized as chemical warfare agents (CWA). OPNA exposure can lead to several neurological, sensory, and motor symptoms that
Chandrakumar Bogguri, Vivek Kurien George, Beheshta Amiri, Alexander Ladd, Nicholas R. Hum, Aimy Sebastian, Heather A. Enright, Carlos A. Valdez, T. Nathan Mundhenk, Jose Cadena, Doris Lam   +10 more
doaj   +2 more sources

Responding to nerve agent poisoning: A guide for emergency nurses. Part 2 [PDF]

, 2020
The release of chemical agents can cause loss of life and result in major incidents. Chemical agent-related major incidents require a modified response by emergency services due to the chemicals’ transmissibility, lethality, latency and persistence.
McGhee, Stephen, Clochesy, John, Finnegan, Alan   +2 more
core   +2 more sources

Instantaneous Degradation of Nerve Agent Simulants using Zirconium-based Metal-organic Polyhedra [PDF]

, 2023
Metal-organic polyhedra (MOPs) are discrete molecules made of metal ions/clusters and organic ligands, and their crystal packing leads to the generation of intrinsic and extrinsic porosity.
Delaney, Radke, Tim , Zuehlsdorff, Kyriakos, Stylianou, Kye, Hunter, Kieran, Brunson, Kimia, Kiaei, Ava, Thomas, Andrzej, Gładysiak, Tim Zuehlsdorff, Kimia Kiaei, Kieran Brunson, Delaney Radke, Kye Hunter, Ava Thomas, Kyriakos Stylianou, Andrzej Gładysiak   +15 more
core   +1 more source

Chromogenic detection of nerve agent mimics [PDF]

, 2008
A new chromogenic protocol for the selective detection of nerve agent mimics is ...
Salvador Gil, Ramón Martínez-Máñez, Costero Nieto, Ana María, Ana M. Costero, Martínez Máñez, Ramón, Parra Álvarez, Margarita, Gil Grau, Salvador, Pedro M. E. Mancini, Santiago Royo, Margarita Parra, Royo, Santiago, Mancini, Pedro M. E., Félix Sancenón, Sancenón Galarza, Felix   +13 more
core   +1 more source

Sex‐based structural and functional MRI outcomes in the rat brain after soman (GD) exposure‐induced status epilepticus

Epilepsia Open, 2023
Objective Exposure to the nerve agent, soman (GD), induces status epilepticus (SE), epileptogenesis, and even death. Although rodent models studying the pathophysiological mechanisms show females to be more reactive to soman, no tangible sex differences ...
Meghan Gage, Suraj S Vasanthi, Christina M Meyer, Nikhil S Rao, Daniel R Thedens, Sridhar S. Kannurpatti, Thimmasettappa Thippeswamy   +6 more
doaj   +1 more source

Thermal Catalytic Decomposition of Dimethyl Methyl Phosphonate Using CuO-CeO₂/γ-Al₂O₃

Applied Sciences, 2022
Chemical warfare agents (CWAs) are highly toxic and fast-acting and are easy to cause large-scale poisoning to humans and livestock after being released. The activated carbon used for CWAs adsorption has disadvantages of limited adsorption capacity, easy
Han Gao, Weimin Kong, Shuyuan Zhou, Xuwei Wang, Qingrong He, Yanchun Dong   +5 more
doaj   +1 more source

Electrochemical Biosensors based on Acetylcholinesterase and Butyrylcholinesterase. A Review

International Journal of Electrochemical Science, 2016
Two cholinesterases are known: acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The both enzymes are presented in the body under physiological conditions and the both enzymes have broad use in pharmacology, toxicology and analyses.
Miroslav Pohanka
doaj   +1 more source

Soman (GD) Rat Model to Mimic Civilian Exposure to Nerve Agent: Mortality, Video-EEG Based Status Epilepticus Severity, Sex Differences, Spontaneously Recurring Seizures, and Brain Pathology

Frontiers in Cellular Neuroscience, 2022
Modeling a real-world scenario of organophosphate nerve agent (OPNA) exposure is challenging. Military personnel are premedicated with pyridostigmine, which led to the development of OPNA models with pyridostigmine/oxime pretreatment to investigate novel
Meghan Gage, Meghan Gage, Nikhil S. Rao, Manikandan Samidurai, Marson Putra, Marson Putra, Suraj S. Vasanthi, Christina Meyer, Chong Wang, Thimmasettappa Thippeswamy, Thimmasettappa Thippeswamy   +10 more
doaj   +1 more source

Nerve agents in honey [PDF]

Science, 2017
Analysis of local honey samples shows global landscape contamination by ...
openaire   +2 more sources

A Reactivator of Organophosphorus Nerve Agent-Inhibited Human Acetylcholinesterase: Characterization, Mechanistic Insights and Design

, 2022
Koh, John T.Organophosphorus nerve agents are highly toxic compounds which pose a threat worldwide. These compounds induce toxicity by covalently binding to the active site serine of acetylcholinesterase, which results in inhibition of the enzyme ...
Cadieux, C. Linn
core   +1 more source