Results 31 to 40 of about 348,995 (347)

Thermal Catalytic Decomposition of Dimethyl Methyl Phosphonate Using CuO-CeO₂/γ-Al₂O₃

Applied Sciences, 2022
Chemical warfare agents (CWAs) are highly toxic and fast-acting and are easy to cause large-scale poisoning to humans and livestock after being released. The activated carbon used for CWAs adsorption has disadvantages of limited adsorption capacity, easy
Han Gao, Weimin Kong, Shuyuan Zhou, Xuwei Wang, Qingrong He, Yanchun Dong   +5 more
doaj   +1 more source

Electrochemical Biosensors based on Acetylcholinesterase and Butyrylcholinesterase. A Review

International Journal of Electrochemical Science, 2016
Two cholinesterases are known: acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The both enzymes are presented in the body under physiological conditions and the both enzymes have broad use in pharmacology, toxicology and analyses.
Miroslav Pohanka
doaj   +1 more source

Soman (GD) Rat Model to Mimic Civilian Exposure to Nerve Agent: Mortality, Video-EEG Based Status Epilepticus Severity, Sex Differences, Spontaneously Recurring Seizures, and Brain Pathology

Frontiers in Cellular Neuroscience, 2022
Modeling a real-world scenario of organophosphate nerve agent (OPNA) exposure is challenging. Military personnel are premedicated with pyridostigmine, which led to the development of OPNA models with pyridostigmine/oxime pretreatment to investigate novel
Meghan Gage, Meghan Gage, Nikhil S. Rao, Manikandan Samidurai, Marson Putra, Marson Putra, Suraj S. Vasanthi, Christina Meyer, Chong Wang, Thimmasettappa Thippeswamy, Thimmasettappa Thippeswamy   +10 more
doaj   +1 more source

Identification and Study of Biomarkers from Novichok-Inhibited Butyrylcholinesterase in Human Plasma

Molecules, 2021
To identify biomarkers of ethyl (1-(diethylamino)ethylidene)phosphoramidofluoridate (A234)- or methyl (1-(diethylamino)ethylidene)phosphoramidofluoridate (A232)-inhibited butyrylcholinesterase (BChE), we investigated nonapeptide adducts containing the ...
Woo-Hyeon Jeong, Jin-Young Lee, Kyoung-Chan Lim, Hyun-Suk Kim   +3 more
doaj   +1 more source

Neurotoxicity [PDF]

, 2014
Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust, Creeley, Feldman, Grandjean, Herken, Panzica, Parent, Pessah, Rice, Román, Spencer, Spencer, Tu, Vinken, Yasui, Zawia   +15 more
core   +2 more sources

Novel Bisquaternary Oximes—Reactivation of Acetylcholinesterase and Butyrylcholinesterase Inhibited by Paraoxon

Molecules, 2009
Four novel bisquaternary aldoxime cholinesterase reactivators differing in their chemical structure were prepared. Afterwards, their biological activity was evaluated for their ability to reactivate acetylcholinesterase (AChE; EC 3.1.1.7) and ...
Daniel Jun, Jana Zdarova Karasova, Miroslav Pohanka, Martina Hrabinova, Kamil Musilek, Martin Paar, Vladimir Cirkva, Jiri Palecek, Kamil Kuca, Lucie Musilova   +9 more
doaj   +1 more source

Postoperative pain management in children: Guidance from the pain committee of the European Society for Paediatric Anaesthesiology (ESPA Pain Management Ladder Initiative) [PDF]

, 2018
The main remit of the European Society for Paediatric Anaesthesiology (ESPA) Pain Committee is to improve the quality of pain management in children. The ESPA Pain Management Ladder is a clinical practice advisory based upon expert consensus to help to ...
Adamek, Akin, Al-Zaben, Alm, Amminnikutty, Amoli, Anderson, Anderson, Antila, Arcioni, Association of Paediatric Anaesthetists of Great Britain and Ireland, Aubrun, Aveline, Aysenur, Bailey, Bailie, Bakan, Baley, Becke, Beers, Bell, Ben-Meir, Bertini, Bhalla, Birmingham, Bouwmeester, Bozkurt, Breitfeld, Breschan, Breschan, Brown, Brown, Büttner, Carstensen, Cha, Chan, Chou, Conti, Cousins, Crellin, Cyna, Dadure, Dadure, Dahi-Taleghani, Dahmani, Dalens, Das, Derry, Derry, Duedahl, Ecoffey, El-Fattah, Elshammaa, Fendrich, Fieler, Finkel, Flack, Fösel, Ganidagli, Gear, Gemma, Ginsberg, Glover, Habre, He, Hicks, Hinz, Holmer Pettersson, Hong, Howard, Hudcova, Huenseler, Huynh, Höhne, Ingelmo, Ivani, Ivani, Ivani, Ivani, Jahr, Jaksch, José María, Ju, Jöhr, Kamata, Kart, Kimiaei Asadi, Kokki, Kokki, Kokki, Kokki, Koppert, Kost-Byerly, Kost-Byerly, Kubica-Cielińska, Kumar, Kurihara, Kwak, Lam, Laskowski, Lavonas, Leclair, Lee, Leksowski, Leoni, Litalien, Liu, Liu, Lorenzo, Lundeberg, Lönnqvist, Lönnqvist, Lönnqvist, Manworren, Marel, Marhofer, Mazoit, McNicol, Merry, Messerer, Messerer, Miller, Miró, Mobley, Mohammed, Momeni, Moriceau, Morton, Morton, Mukherjee, Müller, Mędrzycka-Dąbrowska, O'Sullivan, Olkkola, Orange, Ousley, Pace, Park, Park, Pasero, Petrat, Pierce, Polaner, Qian, Rabbitts, Redmann, Richer, Rugyte, Sahin, Sammartino, Sandeman, Schnabel, Schnabel, Schug, Schug, Schug, Schultz-Machata, Sekhavat, She, Shirazi, Sng, Soh, Sola, Soulard, Southworth, Sowder, Spacek, Splinter, Stamer, Staschen, Steans, Steffen, Subramanyam, Suresh, Taheri, Tobias, Tsuchiya, Valizadeh, Voepel-Lewis, Walker, Walther-Larsen, Walther-Larsen, Wang, Weintraud, Willschke, Willschke, Willschke, Wilson, Wilson-Smith, Wininger, Wong, Wong, Xue, Xue, Yaster, Yildiz, Yung   +196 more
core   +1 more source

Targeted Synthesis of 1-(4-Hydroxyiminomethylpyridinium)-3-pyridiniumpropane Dibromide – A New Nerve Agent Reactivator

Molecules, 2007
Preparation of 1-(4-hydroxy-iminomethylpyridinium)-3-pyridiniumpropane dibromide is described. This compound represents a new acetylcholinesterase (AChE) reactivator, which has no substituents on the second pyridinium ring as found in other commonly used
Jan Marek, Martina Hrabinova, Petr Stodulka, Daniel Jun, Martin Paar, Kamil Musilek, Kamil Kuca   +6 more
doaj   +1 more source

A naphthalimide-based fluorescence-enhanced probe for nerve agent mimics

上海师范大学学报. 自然科学版, 2020
Neurotoxic agents, such as sarin, soman and tauben, are highly toxic organophosphorus compounds, which can be used as chemical weapons.These compounds mainly inhibit the activity of acetylcholine enzymes, which in turn cause nervous system disorders ...
ZHAO Lei, CHEN Kang, CHENG Tanyu
doaj   +1 more source

Chromogenic detection of nerve agent mimics [PDF]

, 2008
A new chromogenic protocol for the selective detection of nerve agent mimics is reported.Costero Nieto, Ana Maria, Ana.Costero@uv.es ; Gil Grau, Salvador, Salvador.Gil@uv.es ; Parra Alvarez, Margarita, Margarita.Parra@uv ...
Ana M. Costero, Bencic-Nagale, Brown, Burnworth, Dale, Eubanks, Félix Sancenón, Giordano, Gooding, Gunnlaugsson, Hewage, Hill, Jr, Ilhan, Jenkins, Jenkins, Jenkins, Kady, Knapton, Létant, Margarita Parra, McBride, McKusick, Minin, Pavlov, Pedro M. E. Mancini, Ramón Martínez-Máñez, Royo, Salvador Gil, Santiago Royo, Shunmugam, Sohn, Southard, Terrier, Trettnak, Van Houten, Wallace, Wallace, Wang, Wang, Zhang   +39 more
core   +2 more sources