Results 41 to 50 of about 348,995 (347)

Characterizing the immune microenvironment of malignant peripheral nerve sheath tumor by PD-L1 expression and presence of CD8+ tumor infiltrating lymphocytes. [PDF]

open access: yes, 2016
BackgroundMalignant peripheral nerve sheath tumor (MPNST) is an aggressive sarcoma with few treatment options. Tumor immune state has not been characterized in MPNST, and is important in determining response to immune checkpoint blockade.
Bernthal, Nicholas   +11 more
core   +2 more sources

TSE pathogenesis in cattle and sheep [PDF]

open access: yes, 2008
Many studies have been undertaken in rodents to study the pathogenesis of transmissible spongiform encephalopathies (TSE). Only a few studies have focused on the pathogenesis of bovine spongiform encephalopathy (BSE) and scrapie in their natural hosts ...
Bossers, A.   +2 more
core   +3 more sources

Characterization of the Interaction of Nerve Agent Mimics with Selected Synthetic Receptors

open access: yesOrganic Materials, 2022
Qualitative NMR spectroscopic and quantitative calorimetric binding studies were performed to characterize the interaction of nontoxic mimics of the V-type nerve agent VX (O-ethyl S-[2-(diisopropylamino)ethyl] methylphosphonothioate) and the Novichok ...
Carolina Braga Barbosa   +3 more
doaj   +1 more source

Detection of Novichok and V-Group Nerve Agents by Chemosensors Containing Nile Blue Chromophore

open access: yesChemosensors
This paper presents the results of experiments aiming for the detection and differentiation of selected nerve agents of the Novichok and V-group using simple strip detectors containing colourimetric indicator, specifically chemosensor Nile Blue A ...
Martin Urban   +4 more
doaj   +1 more source

Therapeutic strategy for facial paralysis based on the combined application of Si-based agent and methylcobalamin

open access: yesBiochemistry and Biophysics Reports, 2022
Facial paralysis results in the decline in the generation of facial expressions and is attributed to several causes. Intractable facial paralysis has a poor prognosis, and new treatments are required.
Yoshihisa Koyama   +13 more
doaj   +1 more source

Biosilica-nanogold composite: Easy-to-prepare catalyst for soman degradation [PDF]

open access: yes, 2019
A very fast single-step biosynthesis of gold nanoparticles (AuNPs) using algal cells of Mallomonas kalinae (MK) is introduced. The average particle size of crystalline AuNPs was approximately 10 nm.
Holišová, Veronika   +7 more
core   +1 more source

Nerve agents in honey [PDF]

open access: yesScience, 2017
Analysis of local honey samples shows global landscape contamination by ...
openaire   +2 more sources

Nerve agents: A clear and present danger to mankind [PDF]

open access: yesScripta Medica, 2019
This editorial is written on the occasion of the 25th anniversary of the infamous sarin and VX terrorist attacks in Japan, in order to increase the awareness of the potential terrorist use of nerve agents and to urge the preparedness to cope with its ...
Stojiljković Miloš P.
doaj  

Nanoparticle drug delivery systems for inner ear therapy: An overview [PDF]

open access: yes, 2017
open7noembargoed_20180701Valente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini, AlessandroValente, Filippo; Astolfi, Laura; Simoni, Edi; Danti, Serena; Franceschini, Valeria; Chicca, Milvia; Martini,
Astolfi, Laura   +6 more
core   +2 more sources

Nerve agent hydrolysis activity designed into a human drug metabolism enzyme. [PDF]

open access: yesPLoS ONE, 2011
Organophosphorus (OP) nerve agents are potent suicide inhibitors of the essential neurotransmitter-regulating enzyme acetylcholinesterase. Due to their acute toxicity, there is significant interest in developing effective countermeasures to OP poisoning.
Andrew C Hemmert   +14 more
doaj   +1 more source

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