Results 241 to 250 of about 4,225,584 (267)
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Colorimetric and fluorescent sensors for detection of nerve agents and organophosphorus pesticides
, 2021Qian Chen +9 more
semanticscholar +1 more source
Organic Phosphorus Compounds—Nerve Agents
Critical Care Clinics, 2005The organic phosphorous compounds (OPC) include both the military grade nerve agents and the organic phosphorous pesticides. The major mechanism of OPC toxicity is through inhibition of acetylcholinesterase in neuronal synapses leading to excess acetylcholine and overstimulation of target organs. Signs and symptoms depend on the affinity of the OPC for
Claudia L. Barthold, Joshua G. Schier
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Handy ratiometric detection of gaseous nerve agents with AIE-fluorophore-based solid test strips
, 2016Exposure to odorless, colorless, tasteless and yet lethal nerve gases could lead to paralysis of the central nervous system, organ failure or even rapid death.
Shuailing Huang +4 more
semanticscholar +1 more source
CHAPTER 3:Toxicology of Organophosphorus Nerve Agents
, 2016Organophosphorus (OP) nerve agents are highly toxic chemicals that act primarily by inhibiting the enzyme acetylcholinesterase, and the most important routes of exposure are ingestion, inhalation and absorption through the skin.
H. Rice
semanticscholar +1 more source
Zirconia/Graphene Oxide Hybrid Micromotors for Selective Capture of Nerve Agents
, 2015Self-propelled zirconia-graphene/Pt hybrid tubular micromotors, prepared by electrochemical template synthesis, are used for both high-affinity capture and isolation of nerve agents.
Virendra V. Singh +4 more
semanticscholar +1 more source
The acute treatment of nerve agent exposure
Journal of the Neurological Sciences, 2006Nerve agents (NA) are simple and cheap to produce but can produce casualties on a massive scale. They have already been employed by terrorist organizations and rogue states on civilians and armed forces alike. By inhibiting the enzyme acetylcholine esterase, NAs prevent the breakdown of the neurotransmitter acetylcholine.
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Biomarkers of Nerve Agents Exposure
2009Nerve agents (OPC) could be used in terrorist acts. Investigation of longer-lived biomarkers for verification of exposure to toxic compounds is important for diagnosis and prognosis of there intoxications. We study the effects of doses of toxic agent and the times expire after intoxications on the potential biomarkers.
Todor A. Popov +5 more
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Neuroactive Agents and Nerve Membrane Conductances [PDF]
The Journal of General Physiology, 1968 John W. Moore, Toshio Narahashi
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Bacterial detoxification of organophosphate nerve agents
Current Opinion in Microbiology, 2002Bacterial enzymes have been isolated that catalyze the hydrolysis of organophosphate nerve agents with high-rate enhancements and broad substrate specificity. Mutant forms of these enzymes have been constructed through rational redesign of the active-site binding pockets and random mutagenesis to create protein variants that are optimized for the ...
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