Results 31 to 40 of about 44,817 (303)
Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes [PDF]
, 2015 Background: NOD-like receptors (Nlrs) are key regulators of immune responses during infection and autoimmunity. A subset of Nlrs assembles inflammasomes, molecular platforms that are activated in response to endogenous danger and microbial ligands and ...
De Winter, Vicky +6 more
core +2 more sources
A sulfated carbohydrate epitope inhibits axon regeneration after injury [PDF]
, 2012 Chondroitin sulfate proteoglycans (CSPGs) represent a major barrier to regenerating axons in the central nervous system (CNS), but the structural diversity of their polysaccharides has hampered efforts to dissect the structure-activity relationships ...
Brown, Joshua M. +14 more
core +2 more sources
Recovery of proprioceptive feedback from nerve crush
The Journal of Physiology, 2011 Non‐Technical Summary Regeneration of muscle nerves damaged by crush reconnects the peripheral limb of neural circuits that pass through the spinal cord, but the mechanisms underlying functional recovery remain uncertain. We examined the actions of natural muscle stretch that initiates muscle contraction, i.e.
Prather, Jonathan F. +6 more
openaire +4 more sources
Critical role of p38 MAPK for regeneration of the sciatic nerve following crush injury in vivo [PDF]
, 2013 BACKGROUND The physiological function of p38α, which is an isoform of p38 MAPK, has been investigated previously in several studies using pharmacological inhibitors.
Atkins, G. +7 more
core +2 more sources
Assessment of outer retinal thickness and function in mice after experimental optic nerve trauma
BMC Ophthalmology, 2022 Background Optic nerve trauma caused by crush injury is frequently used for investigating experimental treatments that protect retinal ganglion cells (RGCs) and induce axonal regrowth.
Karin Rose Lypka +4 more
doaj +1 more source
Printable microscale interfaces for long-term peripheral nerve mapping and precision control [PDF]
, 2019 The nascent field of bioelectronic medicine seeks to decode and modulate peripheral nervous system signals to obtain therapeutic control of targeted end organs and effectors.
Alice E. White +11 more
core +1 more source
Reset Neurectomy for Cutaneous Nerve Injuries
Plastic and Reconstructive Surgery, Global Open, 2021 Summary. Diffuse cutaneous nerve injuries, often caused by a crush mechanism, are challenging for the nerve surgeon. Discrete nerve transections and focal neuromas are easier to identify and have a more distinct treatment algorithm.
Kyle R. Eberlin, MD +3 more
doaj +1 more source
Tracking intracavernously injected adipose-derived stem cells to bone marrow. [PDF]
, 2011 The intracavernous (i.c.) injection of stem cells (SCs) has been shown to improve erectile function in various erectile dysfunction (ED) animal models. However, the tissue distribution of the injected cells remains unknown.
Banie, L +6 more
core +1 more source
Cell Transplantation, 2019 Crush injuries in peripheral nerves are frequent and induce long-term disability with motor and sensory deficits. Due to axonal and myelin sheath disruptions, strategies for optimized axonal regeneration are needed. Multipotent mesenchymal stromal cells (
Diego Noé Rodríguez Sánchez +6 more
doaj +1 more source
Journal of Tissue Engineering, 2022 Injuries within the peripheral nervous system (PNS) lead to sensory and motor deficits, as well as neuropathic pain, which strongly impair the life quality of patients.
Na Zhang +6 more
doaj +1 more source