Results 21 to 30 of about 15,288 (260)

Recovery of proprioceptive feedback from nerve crush

open access: yesThe Journal of Physiology, 2011
Non‐Technical Summary  Regeneration of muscle nerves damaged by crush reconnects the peripheral limb of neural circuits that pass through the spinal cord, but the mechanisms underlying functional recovery remain uncertain. We examined the actions of natural muscle stretch that initiates muscle contraction, i.e.
Prather, Jonathan F.   +6 more
openaire   +5 more sources

LYSOSOMES IN THE RAT SCIATIC NERVE FOLLOWING CRUSH [PDF]

open access: yesThe Journal of Cell Biology, 1965
Peripheral nerves undergoing degeneration are favorable material for studying the types, origins, and functions of lysosomes. The following lysosomes are described: (a) Autophagic vacuoles in altered Schwann cells. Within these vacuoles the myelin and much of the axoplasm which it encloses in the normal nerve are degraded (Wallerian degeneration).
E, Holtzman, A B, Novikoff
openaire   +2 more sources

Skeletal muscle transcriptomics identifies common pathways in nerve crush injury and ageing

open access: yesSkeletal Muscle, 2022
Motor unit remodelling involving repeated denervation and re-innervation occurs throughout life. The efficiency of this process declines with age contributing to neuromuscular deficits.
C. A. Staunton   +6 more
doaj   +1 more source

Reduced Renshaw Recurrent Inhibition after Neonatal Sciatic Nerve Crush in Rats

open access: yesNeural Plasticity, 2014
Renshaw recurrent inhibition (RI) plays an important gated role in spinal motion circuit. Peripheral nerve injury is a common disease in clinic. Our current research was designed to investigate the change of the recurrent inhibitory function in the ...
Liang Shu   +6 more
doaj   +1 more source

Acetyl salicylic acid augments functional recovery following sciatic nerve crush in mice

open access: yesJournal of Brachial Plexus and Peripheral Nerve Injury, 2007
Cyclin-dependent kinase 5 (CDK-5) appears to play a significant role in peripheral nerve regeneration as CDK-5 inhibition retards nerve regeneration following nerve crush. Anti-inflammatory drug acetyl salicylic acid elevates CDK-5 and reduces ischemia –
Gunale Bhagawat K   +3 more
doaj   +1 more source

Retinal ganglion cell survival and axon regeneration in WldS transgenic rats after optic nerve crush and lens injury

open access: yesBMC Neuroscience, 2012
Background We have previously shown that the slow Wallerian degeneration mutation, whilst delaying axonal degeneration after optic nerve crush, does not protect retinal ganglion cell (RGC) bodies in adult rats.
Lorber Barbara   +4 more
doaj   +1 more source

Assessment of outer retinal thickness and function in mice after experimental optic nerve trauma

open access: yesBMC Ophthalmology, 2022
Background Optic nerve trauma caused by crush injury is frequently used for investigating experimental treatments that protect retinal ganglion cells (RGCs) and induce axonal regrowth.
Karin Rose Lypka   +4 more
doaj   +1 more source

Reset Neurectomy for Cutaneous Nerve Injuries

open access: yesPlastic and Reconstructive Surgery, Global Open, 2021
Summary. Diffuse cutaneous nerve injuries, often caused by a crush mechanism, are challenging for the nerve surgeon. Discrete nerve transections and focal neuromas are easier to identify and have a more distinct treatment algorithm.
Kyle R. Eberlin, MD   +3 more
doaj   +1 more source

Canine Adipose-Derived Mesenchymal Stromal Cells Enhance Neuroregeneration in a Rat Model of Sciatic Nerve Crush Injury

open access: yesCell Transplantation, 2019
Crush injuries in peripheral nerves are frequent and induce long-term disability with motor and sensory deficits. Due to axonal and myelin sheath disruptions, strategies for optimized axonal regeneration are needed. Multipotent mesenchymal stromal cells (
Diego Noé Rodríguez Sánchez   +6 more
doaj   +1 more source

Delivery of Wnt inhibitor WIF1 via engineered polymeric microspheres promotes nerve regeneration after sciatic nerve crush

open access: yesJournal of Tissue Engineering, 2022
Injuries within the peripheral nervous system (PNS) lead to sensory and motor deficits, as well as neuropathic pain, which strongly impair the life quality of patients.
Na Zhang   +6 more
doaj   +1 more source

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