Results 41 to 50 of about 44,817 (303)

TRPV1 agonist, capsaicin, induces axon outgrowth after injury via Ca2+/PKA signaling [PDF]

open access: yes, 2018
Preconditioning nerve injuries activate a pro-regenerative program that enhances axon regeneration for most classes of sensory neurons. However, nociceptive sensory neurons and central nervous system neurons regenerate poorly.
DiAntonio, Aaron   +4 more
core   +2 more sources

Overexpressing neurogenic differentiation factor 1 in Müller cells improves retinal function after optic nerve crush injury in adult mice

open access: yesNeural Regeneration Research
Optic nerve injury leads to axonal degeneration and the death of retinal ganglion cells, which ultimately causes vision loss. Notably, current treatments are limited.
Liting Zhong   +7 more
doaj   +1 more source

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine   +14 more
wiley   +1 more source

B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS [PDF]

open access: yes, 2014
Activation of intrinsic growth programs that promote developmental axon growth may also facilitate axon regeneration in injured adult neurons. Here, we demonstrate that conditional activation of B-RAF kinase alone in mouse embryonic neurons is sufficient
Charron, Jean   +12 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Interfacing peripheral nerve with macro-sieve electrodes following spinal cord injury [PDF]

open access: yes, 2017
Macro-sieve electrodes were implanted in the sciatic nerve of five adult male Lewis rats following spinal cord injury to assess the ability of the macro-sieve electrode to interface regenerated peripheral nerve fibers post-spinal cord injury. Each spinal
Birenbaum, Nathan K   +2 more
core   +3 more sources

The Effect of Clioquinol on Nerve Fiber Regeneration Following Nerve Crush Injury

open access: yesJournal of UOEH, 1986
The effect of clioquinol on regeneration of myelinated fibers of the sural nerve in rats was studied. Clioquinol suspended in polyethylen glycol (300 mg/kg body weight/day, test) and polyethylen glycol only (control) were administered for 14 and 21 days starting 7 days before the nerve crush.
S, Shiraishi   +4 more
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Effects of ozone therapy on facial nerve regeneration

open access: yesBrazilian Journal of Otorhinolaryngology
Introduction: Ozone may promote moderate oxidative stress, which increases antioxidant endogenous systems. There are a number of antioxidants that have been investigated therapeutically for improving peripheral nerve regeneration.
Isa Ozbay   +6 more
doaj   +1 more source

Assessment and diagnosis of acute limb compartment syndrome: A literature review [PDF]

open access: yes, 2014
Background: Compartment syndrome is a collection of symptoms that signal increased pressure in the muscle compartment and results in compromised tissue perfusion.
Ali, Parveen   +2 more
core   +2 more sources

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