Results 101 to 110 of about 656,722 (293)

Rescuing axons from degeneration does not affect retinal ganglion cell death

Brazilian Journal of Medical and Biological Research, 2016
After a traumatic injury to the central nervous system, the distal stumps of axons undergo Wallerian degeneration (WD), an event that comprises cytoskeleton and myelin breakdown, astrocytic gliosis, and overexpression of proteins that inhibit axonal ...
S. de Lima, B.S. Mietto, C. Paula, T. Muniz, A.M.B. Martinez, P.F. Gardino   +5 more
doaj   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Memantine Exacerbates Trimethyltin‐Induced Neurodegeneration and Delays Cognitive Impairment Recovery

Neuropsychopharmacology Reports
Trimethyltin (TMT), a type of organotin compound, induces neuronal loss in specific brain regions and cognitive impairments. These changes are transient and followed by recovery, thereby indicating a model of transient brain damage.
Yusuke Onaka, Taro Yamaguchi, Takumu Yamasaki, Koki Morishige, Masanori Yoneyama   +4 more
doaj   +1 more source

Recent Advances in Transparent Microelectrode Device Architecture and Fabrication Strategies for Biomedical Applications

Advanced Materials Technologies, EarlyView.
Transparent microelectrode arrays enable simultaneous optical and electrical electrophysiology with high spatiotemporal resolution, allowing multimodal observations of dynamic biological systems. Advances in materials and device architectures improve device performance by addressing key trade‐offs between optical transparency, impedance, and ...
Michael Abraham Listyawan, Tran Bach Dang, Chi Cong Nguyen, Yee Lap Pong, Tianruo Guo, Thanh Nho Do, Hoang‐Phuong Phan   +6 more
wiley   +1 more source

Polyethylene glycol has immunoprotective effects on sciatic allografts, but behavioral recovery and graft tolerance require neurorrhaphy and axonal fusion

Neural Regeneration Research
Behavioral recovery using (viable) peripheral nerve allografts to repair ablation-type (segmental-loss) peripheral nerve injuries is delayed or poor due to slow and inaccurate axonal regeneration.
Tyler A. Smith, Liwen Zhou, Cameron L. Ghergherehchi, Michelle Mikesh, Cathy Z. Yang, Haley O. Tucker, JuliAnne Allgood, Jared S. Bushman, George D. Bittner   +8 more
doaj   +1 more source

DEGENERATION OF MUSCLE FOLLOWING NERVE INJURY [PDF]

Brain, 1916
n ...
openaire   +2 more sources

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

The thickness of the retinal nerve fiber layer, macula, and ganglion cell‐inner plexiform layer in people with drug‐resistant epilepsy

Epilepsia Open
Objective Using Optical coherence tomography (OCT), we evaluated the association between peripapillary retinal nerve fiber, macular thickness, macular ganglion cell‐inner plexiform layer, and drug resistance.
Yujie Chen, Weixi Xiong, Lu Lu, Xintong Wu, Le Cao, Jiani Chen, Yingfeng Xiao, Josemir W. Sander, Bo Wu, Dong Zhou   +9 more
doaj   +1 more source

Induction of Nitric Oxide and Its Role in Facial Nerve Regeneration According to the Method of Facial Nerve Injury

Antioxidants
Nitric oxide (NO) is an important molecule in cell communication that also plays an important role in many biological processes. Given the dual role of NO in nerve degeneration and regeneration after facial nerve injury, we sought to delve deeper into ...
Yeon Ju Oh, Dong Keon Yon, Yong Sung Choi, Jinseok Lee, Joon Hyung Yeo, Sung Soo Kim, Jae Min Lee, Seung Geun Yeo   +7 more
doaj   +1 more source

THE DEGENERATION OF PERIPHERAL NERVE FIBRES [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1950
E, GUTMANN, J, HOLUBAR
openaire   +2 more sources