Results 211 to 220 of about 175,050 (352)

Calpain inhibitors protect against axonal degeneration in a model of anti-ganglioside antibody-mediated motor nerve terminal injury [PDF]

, 2003
Graham M. O’Hanlon
openalex   +1 more source

Neuroglobin effectively halts vision loss in Harlequin mice at an advanced stage of optic nerve degeneration

, 2021
Hélène Cwerman‐Thibault, Christophe Lechauve, Vassilissa Malko-Baverel, Sébastien Augustin, Gwendoline Le Guilloux, Élodie Reboussin, Julie Dégardin-Chicaud, Manuel Simonutti, Thomas Debeir, Marisol Corral‐Debrinski   +9 more
openalex   +1 more source

Lesion Site‐Targeted Microspheres Modulate Nav1.7‐Related Signaling for Osteoarthritis Treatment

Advanced Science, EarlyView.
Cartilage‐targeted carbamazepine‐loaded WYRGRL‐modified composite microspheres (CBZ/WCOM) anchor to exposed type II collagen in osteoarthritic lesions and release carbamazepine under acidic conditions. This bind‐then‐release platform modulates Nav1.7‐related sodium signaling, Na⁺/Ca²⁺ exchanger‐associated Ca2+ dynamics, and heat shock protein 70 ...
Cheng Chen, Jiaying Li, Jinjin Ma, Xiaonan Yuan, Yao Xiao, Yang Zhang, Yuan Chen, Hao Jiang, Hui He, Jie Hu, Qianglong Chen, Jinniu Zhang, Bin Li, Yun Zhou, Fengxuan Han, Yong Wang   +15 more
wiley   +1 more source

miR-27a-3p Upregulation and Netrin-1 Deficiency Drive Inflammatory Responses and Nerve Degeneration in Patients With Diabetes. [PDF]

Eur J Neurol
Mondal A, Banerjee S, Naskar S, Bose C, Saha C, Pramanik S, Mukherjee B, Jati P, Sahana PK, Malik RA, Mukhopadhyay S.   +10 more
europepmc   +1 more source

Evaluation of Nicotinamide Riboside in Prevention of Small Nerve Fiber Axon Degeneration and Promotion of Nerve Regeneration [PDF]

Simone Thomas, Remi Ben‐Davies, Aysel Cetinkaya‐Fisgin, Xindan Hu, Xiaoling Li, Sarah Stewart, Baohan Pan, Jeffery L. Twiss, Rajiv R. Ratan, Dianna E. Willis, Michael Polydefkis, Ahmet Höke   +11 more
openalex   +1 more source

Targeting Dnmt3a/m5C/RelA Axis Attenuates Microglia Inflammatory Response and Improves Postoperative Recovery in Chronic Compressive Cervical Spinal Cord Injury

Advanced Science, EarlyView.
A pro‐inflammatory microglial subset persists after decompression in chronic compressive cervical spinal cord injury and shows enhanced Dnmt3a‐driven m5C signaling. By stabilizing RelA mRNA, this axis sustains NF‐κB activation and postoperative neuroinflammation.
Tianyu Qin, Yuan Jiang, Yongheng Xie, Huanwei Qu, Wenbin Yan, Jingle Chen, Yining Chen, Huayi Li, Naibo Feng, Jiajun Wu, Chao Zhang, Zhengqi Huang, Ming Shi, Zhihuai Deng, Guozhi Xiao, Houqing Long   +15 more
wiley   +1 more source

TLR4 deletion reduces small fiber sensory abnormalities and nerve degeneration in diabetic male mice. [PDF]

Neuroscience
Crowards S, Ryals J, Heslop L, Hauser W, Totta-Griese G, Madden T, Wright DE.   +6 more
europepmc   +1 more source

Nerve growth factor delays retinal degeneration in C3H mice

, 1996
The aim of the present study was to investigate the biological role of nerve growth factor (NGF) on retinal degeneration in the C3H mouse strain. This strain is characterized by a single gene mutation (rd) which leads to photoreceptor degeneration ...
LAMBIASE, ALESSANDRO, Aloe, L.
core  

Autonomic nerve dysfunction in patients with spinocerebellar degeneration.

, 1990
Hajime Nakagawa, Yukio Watanabe, Ken-ich Kanda, Naoki Ohashi, Kanemasa Mizukoshi   +4 more
openalex   +2 more sources

PRMT9 Aggravated Dopaminergic Neurodegeneration in Parkinson's Disease Model by Facilitating the Degradation of DUSP26 and Inducing Mitochondrial Dysfunction

Advanced Science, EarlyView.
In the pathological state of PD induced by MPP+, the upregulated PRMT9 in dopaminergic neurons translocates into mitochondrion and interacts with DUSP26 and catalyzes its arginine methylation, leading to the ubiquitin‐proteasomal degradation of DUSP26 mediated by Trim32.
Tengfei Liu, Xiaomeng Song, Xin Guo, Rui Xiao, Ru Sun, Qiuran Ji, Lu Yu, Yiquan Li, Qingyi Fu, Qidi Xue, Lingjun Kong, Lin Chen, Chengjiang Gao, Huiqing Liu   +13 more
wiley   +1 more source