Results 281 to 290 of about 1,223,403 (400)

Carbamazepine Alleviates Retinal and Optic Nerve Neural Degeneration in Diabetic Mice via Nerve Growth Factor-Induced PI3K/Akt/mTOR Activation [PDF]

, 2019
Nehal M. Elsherbiny, Yousra Abdel–Mottaleb, Amany Y. Elkazaz, Hoda Atef, Rehab M. Lashine, Amal M. Youssef, Wessam Ezzat Morsy, Sabah H. El-Ghaiesh, Rabie E. Elshaer, Mohamed El‐Shafey, Sawsan A. Zaitone   +10 more
openalex   +1 more source

PRMT3‐Mediated H4R3me2a Promotes Primary Age‐Related Tauopathy by Driving Tau Hyperphosphorylation in Neuron

Advanced Science, EarlyView.
This study identifies PRMT3‐mediated H4R3me2a as a critical driver of tau hyperphosphorylation in primary age‐related tauopathy. Mechanistic insights reveal that the PRMT3/H4R3me2a/miR‐448 axis suppresses IGF1R expression via epigenetic regulation, further dysregulating the PI3K/AKT/GSK3β pathway.
Haotian Liu, Xinnan Liu, Fengyuan Tian, Yashuang Chen, Jingying Li, Xue Wang, Wenying Qiu, Xia Wang, Chao Ma, Wei Ge   +9 more
wiley   +1 more source

Deletion of SIRPα (signal regulatory protein-α) promotes phagocytic clearance of myelin debris in Wallerian degeneration, axon regeneration, and recovery from nerve injury [PDF]

, 2019
Gerard Elberg, Sigal Liraz‐Zaltsman, Fanny Reichert, Takashi Matozaki, Michael Tal, Shlomo Rotshenker   +5 more
openalex   +1 more source

The excimer lamp induces cutaneous nerve degeneration and reduces scratching in a dry-skin mouse model.

Journal of Investigative Dermatology, 2014
A. Kamo, M. Tominaga, Y. Kamata, K. Kaneda, K. Ko, H. Matsuda, Utako Kimura, H. Ogawa, K. Takamori   +8 more
semanticscholar   +1 more source

Astrocytic ET‐1 System Determines Microglia Phenotype Following Spinal Cord Injury

Advanced Science, EarlyView.
The study reveals that astrocytic ET‐1 system is solely activated by thrombin following SCI via RhoA/NF‐κB and MAPKs/NF‐κB signal pathway. The release of astrocytic ET‐1 drives microglia polarization toward M1 phenotype through YAP signaling via ETA and ETB receptors.
Bingqiang He, Si Xu, Mengdi Li, Hui Li, Shaolan Li, Li Niu, Honghua Song, Rixin Cai, Yue Zhou, Zhilong Cao, Yingjie Wang, Yongjun Wang   +11 more
wiley   +1 more source

Retinal and optic nerve degeneration in patients with multiple sclerosis followed up for 10 years [PDF]

, 2019
Elisa Viladés Palomar, Elvira Orduna‐Hospital, M.J. Rodrigo Sanjuán, J.G. Larrea Samper, Elena García‐Martín   +4 more
openalex   +1 more source

Understanding the Metal‐Center Mediated Adsorption and Redox Mechanisms in a FeMn(NbTa)2O6 Columbite Material for Anion Exchange Membrane Water Electrolyzers

Advanced Energy Materials, EarlyView.
FeMn(NbTa)2O6‐columbite is a sustainable and high‐performance bifunctional electrocatalyst for anion exchange membrane water electrolyzers, comparable to benchmark catalysts. In situ XAS and DFT analysis show Fe/Mn sites exhibit higher OER activity due to reduced overpotentials and favorable O→OOH energetics. The Nb/Ta sites facilitate charge transfer,
Patrick M. Bacirhonde, Devendra Shrestha, Kyoungin Kang, Esensil Man Hia, Nikhil Komalla, Nelson Y. Dzade, Merve Buldu‐Akturk, Michelle P. Browne, Milan Babu Poudel, Dong Jin Yoo, Eun‐Suk Jeong, Ahmed Yousef Mohamed, Byoung Gun Han, Deok‐Yong Cho, Matthew T. Curnan, Geun Ho Gu, Jeong Woo Han, Chan Hee Park   +17 more
wiley   +1 more source

Faculty Opinions recommendation of Adding insult to injury: cochlear nerve degeneration after "temporary" noise-induced hearing loss.

, 2010
Tobias Moser
openalex   +1 more source

Cell Membrane‐Coated Lipid Nanoparticles for Drug Delivery

Aggregate, EarlyView.
This review highlights recent progress in cell membrane‐coated lipid nanoparticles (CMC‐LNPs), focusing on their design, preparation methods, functional integration, and biomedical applications. It discusses various types of LNPs and coating strategies, characterization techniques, therapeutic functions, and applications.
Moataz B. Zewail, Guangze Yang, Yilong Fan, Yue Hui, Chun‐Xia Zhao, Yun Liu   +5 more
wiley   +1 more source

Optical analysis of facial nerve degeneration in Bell’s palsy

, 2021
Hadas Lupa Yitzhak, Michael Wolf, Nisan Ozana, Yarden Tzabari Kelman, Zeev Zalevsky   +4 more
openalex   +1 more source