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The chemistry of nerve degeneration

, 1913
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Brain imaging signature of neuropathic pain phenotypes in small-fiber neuropathy: altered thalamic connectome and its associations with skin nerve degeneration.

Pain, 2020
Small-fiber neuropathy (SFN) has been traditionally considered as a pure disorder of peripheral nervous system, characterized by neuropathic pain and degeneration of small-diameter nerve fibers in the skin.
C. Chao, M. Tseng, Yea-Huey Lin, Paul-Chen Hsieh, Chien-Ho Lin, Shin-Leh Huang, S. Hsieh, M. Chiang   +7 more
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Electrical stimulation accelerates Wallerian degeneration and promotes nerve regeneration after sciatic nerve injury

Glia, 2022
Following peripheral nerve injury (PNI), Wallerian degeneration (WD) in the distal stump can generate a microenvironment favorable for nerve regeneration.
Xiangling Li, Tieyuan Zhang, Chaochao Li, Wen-jing Xu, Y. Guan, Xiaoya Li, Haofeng Cheng, Shengfeng Chen, Boyao Yang, Yuli Liu, Zhiqi Ren, Xiangyu Song, Zhibo Jia, Yu Wang, Jinshu Tang   +14 more
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NERVE DEGENERATION IN POLIOMYELITIS

Archives of Neurology & Psychiatry, 1932
For purposes of comparison with the degenerating fibers of nerves and roots from monkeys killed during the acute stage of poliomyelitis, it was deemed advisable to study by physiologic and histologic methods normal nerves severed from their cells of origin.
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Chemical degeneration of intestinal nerves

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1990
In 15 dogs, cobalt chloride solutions were infused close intra-arterially to perfuse a short segment of the jejunum. In an additional four dogs, the jejunum was perfused with the aqueous vehicle (perfusion control). All animals were killed after 1 mo and tissue samples from cobalt-treated and from nonperfused intestine (tissue comparison control) were
C T, Frantzides, J C, Garancis, B T, Doumas, R E, Condon   +3 more
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OPTIC NERVE DEGENERATION IN ALZHEIMERʼS DISEASE

Journal of Neuropathology and Experimental Neurology, 1986
Alzheimer's disease is a dementing disorder of unknown cause in which there is degeneration of neuronal subpopulations in the central nervous system. In postmortem studies, we found widespread axonal degeneration in the optic nerves of 8 of 10 patients with Alzheimer's disease.
D R, Hinton, A A, Sadun, J C, Blanks, C A, Miller   +3 more
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Ischemic Degeneration of Nerve Fibers

Archives of Neurology, 1960
Direct evidence that nerve fiber degeneration may follow occlusion of groups of regional vasa nervorum, although provided by the experiments of Okada 17 (1905), Adams 1 (1943), Durward 11 (1948), and Roberts 19 (1948), has been scanty, and the conclusions to be drawn from the highly variable, but mainly negative, results of these experiments are ...
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Peripheral Nerve Glycolysis in Wallerian Degeneration

Archives of Neurology, 1967
Although lLTHOUGH no completely satisfactory explanation for the changes occurring in the transected nerve has been established, nevertheless, changes in some enzymes associated with experimental wallerian degeneration have been reported. Most prominent among these are acetylcholinesterase, phosphatases, succinic dehydrogenase, and β-glucuronidase. 1-8
I, DeSibrik, D, O'Doherty
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Cochlear Nerve Degeneration Coincident With Adrenocerebroleukodystrophy

Archives of Otolaryngology - Head and Neck Surgery, 1976
A 19-month-old boy had adrenocerebroleukodystrophy and unusually severe cochlear nerve degeneration and demyelination, a condition in advance of that expected from known disease entities. We report the only known temporal bone study in adrenocerebroleukodystrophy.
M, Igarashi, J G, Neely, P F, Anthony, B R, Alford   +3 more
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Muscle degeneration following remote nerve injury

Journal of Neurobiology, 1998
Muscle depends upon innervation and contraction to maintain a differentiated state. Denervation can therefore induce muscle atrophy. In grasshoppers, muscle degeneration can also be triggered by the severing of a leg during autotomy. In this case, the muscles that degenerate are neither damaged nor denervated.
K E, Personius, E A, Arbas
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