Sural nerve involvement in experimental hypertension: morphology and morphometry in male and female normotensive Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR) [PDF]
Background The sural nerve has been widely investigated in experimental models of neuropathies but information about its involvement in hypertension was not yet explored.
Sanada Luciana+5 more
doaj +5 more sources
Electrical neurostimulation for chronic pain: on selective relay of sensory neural activities in myelinated nerve fibers [PDF]
Chronic pain affects about 100 million adults in the US. Despite their great need, neuropharmacology and neurostimulation therapies for chronic pain have been associated with suboptimal efficacy and limited long-term success, as their mechanisms of action are unclear. Yet current computational models of pain transmission suffer from several limitations.
Anderson, William S.+3 more
arxiv +4 more sources
Nerve Preparation and Recordings for Pharmacological Tests of Sensory and Nociceptive Fiber Conduction Ex Vivo [PDF]
Measuring signal propagation through nerves is a classical electrophysiological technique established decades ago to evaluate sensory and motor functions in the nervous system.
Volodymyr Krotov, Olga Kopach
doaj +3 more sources
The effects of normal aging on myelinated nerve fibers in monkey central nervous system
The effects of aging on myelinated nerve fibers of the central nervous system are complex. Many myelinated nerve fibers in white matter degenerate and are lost, leading to some disconnections between various parts of the central nervous system.
Alan Peters
doaj +2 more sources
The mechanosensitive ion channel TRAAK is localized to the mammalian node of Ranvier [PDF]
TRAAK is a membrane tension-activated K+ channel that has been associated through behavioral studies to mechanical nociception. We used specific monoclonal antibodies in mice to show that TRAAK is localized exclusively to nodes of Ranvier, the action ...
Stephen G Brohawn+5 more
doaj +3 more sources
Asymptotic construction of pulses in the Hodgkin Huxley model for myelinated nerves [PDF]
A quantitative description of pulses and wave trains in the spatially discrete Hodgkin-Huxley model for myelinated nerves is given. Predictions of the shape and speed of the waves and the thresholds for propagation failure are obtained. Our asymptotic predictions agree quite well with numerical solutions of the model and describe wave patterns ...
Carpio, A.
arxiv +6 more sources
Background The dental pulp is a common source of pain and is used to study peripheral inflammatory pain mechanisms. Results show most fibers are unmyelinated, yet recent findings in experimental animals suggest many pulpal afferents originate from fibers
Henry Michael A+2 more
doaj +2 more sources
The vagus nerve provides motor, sensory, and autonomic innervation of multiple organs, and electrical vagus nerve stimulation (VNS) provides an adjunctive treatment option for e.g. medication-refractory epilepsy and treatment-resistant depression.
L. Havton+10 more
semanticscholar +1 more source
Optical Modeling and Characterization of Demyelinated Nerve Using Graphene-Based Photonic Structure
The myelin sheath, as an insulation layer in nerve cells, plays an essential role in neural communication and signal conduction. Loss of myelin, referred to as demyelination, is associated with many mental disorders. Detecting the tiny demyelinated parts
Amir Maghoul+5 more
doaj +1 more source
Structural and molecular characteristics of axons in the long head of the biceps tendon [PDF]
The innervation of the long head of the biceps tendon (LHBT) is not sufficiently documented. This is a drawback since pathologies of the LHBT are a major source of shoulder pain.
Blumer, Roland+7 more
core +1 more source