Results 61 to 70 of about 113,844 (214)

Single-channel recording in myelinated nerve fibers reveals one type of Na channel but different K channels.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1989
Amphibian myelinated nerve fibers were treated with collagenase and protease. Axons with retraction of the myelin sheath were patch-clamped in the nodal and paranodal region. One type of Na channel was found. It has a single-channel conductance of 11 pS (
P. Jonas   +3 more
semanticscholar   +1 more source

Multi‐Scale Modeling of a 3D Soft Magnetoelectric Patch for Wireless Nerve Stimulation

open access: yesAdvanced Materials Interfaces, EarlyView.
Core‐shell, magnetoelectric nanoparticles (MENPs) can serve as wireless electric nano‐sources, thanks to their ability to generate high levels of electricity, when stimulated by a human‐safe external magnetic field. By combining MENPs with soft, biocompatible polymeric matrices and optimizing its composite configuration and electrical behavior via ...
Giulia Suarato   +6 more
wiley   +1 more source

Analysis of current density and related parameters in spinal cord stimulation [PDF]

open access: yes, 1998
A volume conductor model of the spinal cord and surrounding anatomical structures is used to calculate current (and current density) charge per pulse, and maximum charge density per pulse at the contact surface of the electrode in the dorsal epidural ...
Boom, Herman B.K.   +2 more
core   +3 more sources

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang   +9 more
wiley   +1 more source

Modulation of Calcitonin, Parathyroid Hormone, and Thyroid Hormone Secretion by Electrical Stimulation of Sympathetic and Parasympathetic Nerves in Anesthetized Rats

open access: yesFrontiers in Neuroscience, 2017
The thyroid and parathyroid glands are dually innervated by sympathetic (cervical sympathetic trunk [CST]) and parasympathetic (superior laryngeal nerve [SLN]) nerve fibers.
Harumi Hotta   +4 more
doaj   +1 more source

Contribution of Skin Biopsy in Peripheral Neuropathies

open access: yesBrain Sciences, 2020
In the last three decades the study of cutaneous innervation through 3 mm-punch-biopsy has provided an important contribution to the knowledge of small fiber somatic and autonomic neuropathies but also of large fiber neuropathies.
Maria Nolano   +3 more
doaj   +1 more source

Simulation of impedance changes with a FEM model of a myelinated nerve fibre [PDF]

open access: yes2019 J. Neural Eng. 16 056026, 2019
Objective: Fast neural Electrical Impedance Tomography (EIT) is a method which permits imaging of neuronal activity in nerves by measuring the associated impedance changes (dZ). Due to the small magnitudes of dZ signals, EIT parameters require optimization, which can be done using in silico modelling: apart from predicting the best parameters for ...
arxiv   +1 more source

The structural and functional integrity of peripheral nerves depends on the glial-derived signal desert hedgehog [PDF]

open access: yes, 2006
We show that desert hedgehog ( dhh), a signaling molecule expressed by Schwann cells, is essential for the structural and functional integrity of the peripheral nerve.
Jessen, KR   +6 more
core  

Neuronal FGF13 Inhibits Mitochondria‐Derived Damage Signals to Prevent Neuroinflammation and Neurodegeneration in a Mouse Model of Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
This study elucidates a novel role of FGF13 in manipulating neuronal fate via mitochondrial transfer. FGF13 is identified as a mitochondria‐stabilizing protein by interacting with mitochondrial proteins. Under stress, the decrease of neuronal FGF13 fails to retain mitochondria within the cytoplasm, leading to the release of damaged mitochondria to ...
Nanshan Song   +15 more
wiley   +1 more source

The Cutaneous Biopsy for the Diagnosis of Peripheral Neuropathies: Meissner’s Corpuscles and Merkel’s Cells [PDF]

open access: yes, 2018
Cutaneous biopsy is a complementary method, alternative to peripheral nerve biopsy, for the analysis of nerve involvement in peripheral neuropathies, systemic diseases, and several pathologies of the central nervous system.
Alba, Elda   +8 more
core   +2 more sources

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