Results 71 to 80 of about 39,260 (248)

Immune or genetic-mediated disruption of CASPR2 causes pain hypersensitivity due to enhanced primary afferent excitability [PDF]

, 2018
Human autoantibodies to contactin-associated protein-like 2 (CASPR2) are often associated with neuropathic pain, and CASPR2 mutations have been linked to autism spectrum disorders, in which sensory dysfunction is increasingly recognized.
Bennett, David L., Buckley, Camilla, Carroll, Liam, Cervellini, Ilaria, Chisholm, Kim I., Clark, Alex J, Coutinho, Ester, Dawes, John M., Dickenson, Anthony H., Galino, Jorge, Giannoccaro, Maria Pia, Gutierrez-Mecinas, Maria, Iwagaki, Noboru, Jacobson, Leslie, Kuehn, Hannah, Kühnemund, Johannes, Lang, Bethan, Leite, M Isabel, Lewin, Gary R., McMahon, Stephen B., Menassa, David A., Middleton, Steven J., Patel, Ryan, Peck, Liam J., Peles, Elior, Pettingill, Philippa, Sanna, Maria D., Shakir, Akila, Sheridan, Joseph, Tewari, Damini, Themistocleous, Andreas C., Todd, Andrew J., Trendafilova, Teodora, Vincent, Angela, Walcher, Jan, Weir, Greg A., Werynska, Karolina, West, Steven J., Wildner, Hendrik, Zeilhofer, Hanns Ulrich   +39 more
core   +2 more sources

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

The Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose, Nicolae Radu, Mugurel Constantin Rusu   +2 more
wiley   +1 more source

Contribution of Skin Biopsy in Peripheral Neuropathies

Brain Sciences, 2020
In the last three decades the study of cutaneous innervation through 3 mm-punch-biopsy has provided an important contribution to the knowledge of small fiber somatic and autonomic neuropathies but also of large fiber neuropathies.
Maria Nolano, Stefano Tozza, Giuseppe Caporaso, Vincenzo Provitera   +3 more
doaj   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

Automated tracing of myelinated axons and detection of the nodes of Ranvier in serial images of peripheral nerves [PDF]

, 2015
The development of realistic neuroanatomical models of peripheral nerves for simulation purposes requires the reconstruction of the morphology of the myelinated fibres in the nerve, including their nodes of Ranvier.
Andres, Andriyenko, Auer, Berclaz, Breiman, Cardona, da Silva, Denk, Feria-Velasco, Frangi, Funke, Funke, Gierthmuehlen, Helmstaedter, Huelsenbeck, Hunter, Karnovsky, Kim, Kreshuk, Kuhn, Li, Li, Lindeberg, Liu, Lou, More, Novas, Nunez-Iglesias, Plachta, Plachta, Ramachandran, Romero, Sato, Schindelin, Schultze, Smith, Sommer, Vazquez-Reina, Vita, Yang, Zhang   +40 more
core   +1 more source

Force stimulation promotes nerve regeneration by restoring cellular energy

BMEMat, EarlyView.
Mechanical stimulation can help nerves regenerate in various ways. We developed two devices (a piezo‐motor‐driven stretching device and a SAW‐based actuator) to apply mechanical stimulation to sciatic nerve and DRG neurons. Our study shows that appropriate mechanical force stimulation can promote regeneration by restoring the energy supply to the ...
Zhe Wang, Chen Cai, Hetao Xie, Yupeng Yang, Lei Li, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Meiwan Chen, Yuanhua Sang, Bing Ji, Zenan Wang   +10 more
wiley   +1 more source

Myelin Basic Protein and Cardiac Sympathetic Neurodegeneration in Nonhuman Primates

Neurology Research International, 2021
Minimal myelination is proposed to be a contributing factor to the preferential nigral neuronal loss in Parkinson’s disease (PD). Similar to nigral dopaminergic neurons, sympathetic neurons innervating the heart have long, thin axons which are ...
Jeanette M. Metzger, Helen N. Matsoff, Don Vu, Alexandra D. Zinnen, Kathryn M. Jones, Viktoriya Bondarenko, Heather A. Simmons, Colleen F. Moore, Marina E. Emborg   +8 more
doaj   +1 more source

3D Neuro-electronic interface devices for neuromuscular control: Design studies and realisation steps [PDF]

, 1995
In order to design the shape and dimensions of new 3D multi-microelectrode information transducers properly, i. e. adapted to the scale of information delivery to and from peripheral nerve fibres, a number of studies were, and still are, being performed ...
Frieswijk, Theo A., Meier, Jan H., Rozijn, Tom H., Rutten, Wim L.C., Smit, Jos P.A.   +4 more
core   +2 more sources

The association between neural crest‐derived glia and melanocyte lineages throughout development and disease

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient cell population that emerges from the dorsal neural tube during neurulation and migrates extensively throughout the embryo. Among their diverse derivatives, glial cells (such as Schwann and satellite ganglionic cells) and melanocytes represent two major lineages. In vitro studies suggested they share a common
Chaya Kalcheim
wiley   +1 more source

Selective Fiber Degeneration in the Peripheral Nerve of a Patient With Severe Complex Regional Pain Syndrome

Frontiers in Neuroscience, 2018
Aims: Complex regional pain syndrome (CRPS) is characterized by chronic debilitating pain disproportional to the inciting event and accompanied by motor, sensory, and autonomic disturbances. The pathophysiology of CRPS remains elusive.
Adrien Yvon, Adrien Yvon, Alessandro Faroni, Adam J. Reid, Adam J. Reid, Vivien C. Lees   +5 more
doaj   +1 more source