Results 71 to 80 of about 23,201 (210)

Structural reorganization of the sciatic, peroneal, and tibial nerves during osteosynthesis of lower leg fracture and after fracture consolidation (an experimental study)

Анналы клинической и экспериментальной неврологии, 2017
The study purpose was to identify histological changes in the peripheral nerves and determine functional significance of subclinical neuropathy in experimental simulation of lower leg fractures.
T. N. Varsegova, N. A. Shchudlo, M. M. Shchudlo, M. A. Stepanov, M. S. Sayfutdinov   +4 more
doaj   +1 more source

Anatomical and functional mapping of vagal nociceptive sensory nerve subsets innervating the mouse lower airways by intersectional genetics

The Journal of Physiology, EarlyView.
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil, Justin Shane Hooper, Seol‐Hee Kim, Parmvir K. Bahia, Nika Pavelkova, Sanjay S. Nair, Teresa S. Darcey, Karina V. Lurye, Meghana Madaram, Jailene Fiallo, Stephen H. Hadley, Thomas E. Taylor‐Clark   +11 more
wiley   +1 more source

A quantitative evaluation of gross versus histologic neuroma formation in a rabbit forelimb amputation model: potential implications for the operative treatment and study of neuromas

Journal of Brachial Plexus and Peripheral Nerve Injury, 2011
Background Surgical treatment of neuromas involves excision of neuromas proximally to the level of grossly "normal" fascicles; however, proximal changes at the axonal level may have both functional and therapeutic implications with regard to amputated ...
Kuiken Todd A, Ding Xianzhong, O'Shaughnessy Kristina D, Kim Peter S, Ko Jason H, Dumanian Gregory A   +5 more
doaj   +1 more source

High‐altitude headache: Insights into pathophysiology and potential treatment implications

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla, Florian Frank, Giacomo Strapazzon, Justin Lawley   +3 more
wiley   +1 more source

Hypoxia‐induced vulnerability of the somatosensory nervous system

The Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

Comparison Outcome of Nerve Regeneration across an Eggshell Membrane Guidance Channel and Autograft

Caspian Journal of Neurological Sciences, 2016
Background: Peripheral nerves may be damaged during an injury and its current standard treatment is using an autologous nerve. Objectives: The purpose of this experimental study is to evaluate and compare the histological results of nerve regeneration ...
Gholam-Hossein Farjah, Malak-Sadat Naeimi, Ali Saberi   +2 more
doaj  

Modelling the memory of unmyelinated axons: Integration of a data‐driven approach with physiological memory concept

The Journal of Physiology, EarlyView.
Abstract figure legend Simplified and resource‐efficient computational model for predicting activity‐dependent conduction velocity changes in individual spikes within spike trains in unmyelinated axons. Fibre memory: The conduction speed of each action potential is modulated non‐linearly by the axon's prior activity.
Anna Maxion, Jenny Tigerholm, Barbara Namer, Ekaterina Kutafina   +3 more
wiley   +1 more source

The role of group III/IV afferent feedback in the ventilatory, pressor and metabolic responses to exercise in normoxia and hypoxia

The Journal of Physiology, EarlyView.
Abstract figure legend Participants completed cycling exercise with (placebo) and without (25 µg intrathecal fentanyl) intact group III/IV muscle afferent feedback in three settings: normoxia, acute hypoxia and chronic hypoxia after 7–9 days of acclimatisation (∼3800 m). Blocking afferent feedback suppressed exercise hyperpnoea across all environments,
Elliott J. Jenkins, Phuong L. Ha, Connor A. Howe, Jay M. J. R. Carr, Justin A. Monteleone, Andrew J. M. Douglas, Abigail Nicholson, Andrew Steele, Brydie Lemkes, Jodie L. Koep, L. Madden Brewster, Jennifer Duffy, Mathew I. B. Debenham, Tena Monaghan, Declan Isaak, Jacob McCormick, Brian H. Dalton, Chris J. McNeil, Jared Baylis, David MacLeod, Mike Stembridge, Markus Amann, Philip N. Ainslie, Travis D. Gibbons   +23 more
wiley   +1 more source

Peripheral regeneration of Aβ low‐threshold mechanoreceptors is limited despite activation of regenerative transcriptional pathways

The Journal of Physiology, EarlyView.
Abstract figure legend The regeneration of Aβ low‐threshold mechanoreceptors (Aβ‐LTMRs), sensory neurons responsible for discriminative touch, has not previously been explored. Here, we took advantage of the selective expression of Calb1 in Aβ‐LTMRs to generate two genetic mouse models for studying their regenerative response after nerve injury.
Sara Bolívar, Natàlia Martínez‐Mateu, David Ovelleiro, Esther Udina   +3 more
wiley   +1 more source

Satellite Glial Cells Synthesize and Release GABA to Activate Extrasynaptic GABAA Receptors That Modulate Dorsal Root Ganglia Neuron Excitability

Glia, Volume 74, Issue 9, September 2026.
Mechanism of synthesis, release, receptor activation, uptake, and degradation of GABA in dorsal root ganglia (DRG). Left: GABA is synthesized from putrescine in satellite glial cells (SGCs). After being released by Best1 channel, it activates GABAA receptors in sensory neurons, producing a chloride current.
Natalie Jiménez‐Barrios, Ricardo González‐Ramírez, Francisco Javier Paz‐Bermúdez, Guadalupe Raya‐Tafolla, José Segovia Vila, Ricardo Felix, Rodolfo Delgado‐Lezama, Benjamín Florán Garduño   +7 more
wiley   +1 more source