Perturbations in neuroinflammatory pathways are associated with paclitaxel-induced peripheral neuropathy in breast cancer survivors. [PDF]
, 2019 Paclitaxel is a common chemotherapy drug associated with the development of chronic paclitaxel-induced peripheral neuropathy (PIPN). PIPN is associated with neuroinflammatory mechanisms in pre-clinical studies.
Abrams, Gary +9 more
core
ATF3 upregulation in glia during Wallerian degeneration: differential expression in peripheral nerves and CNS white matter [PDF]
, 2004 Background: Many changes in gene expression occur in distal stumps of injured nerves but the transcriptional control of these events is poorly understood.
Anderson, PN +6 more
core +3 more sources
Characteristics of Cerebral Palsy in the Midwestern US
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim +6 more
wiley +1 more source
The Physiologic Basis of Molecular Therapeutics for Peripheral Nerve Injury: A Primer
Journal of Hand Surgery Global OnlinePeripheral nerve injuries affect a significant number of patients who experience trauma affecting the hand and upper extremity. Improving unsatisfactory outcomes from repair of these injuries remains a clinical challenge despite advancements in ...
Marie C. Spezia, MSc +2 more
doaj +1 more source
Pseudotumor cerebri syndrome in childhood : incidence, clinical profile and risk factors in a national prospective population-based cohort study [PDF]
, 2017 Aim To investigate the epidemiology, clinical profile and risk factors of pseudotumor cerebri syndrome (PTCS) in children aged 1-16 years. Methods A national prospective population-based cohort study over 25 months.
Dean, Fiona +8 more
core +3 more sources
Nerve Excitability in Asymptomatic Carriers and Amyotrophic Lateral Sclerosis Patients With C9orf72
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We investigated the effects of C9orf72 mutation carriership on peripheral nerve excitability in asymptomatic individuals from families with a history of C9orf72 amyotrophic lateral sclerosis (ALS) and patients. Methods We included 47 asymptomatic individuals from families with a history of C9orf72 ALS, of whom 23 were carriers (C9 ...
Diederik J. L. Stikvoort García +3 more
wiley +1 more source
Predicting Axonal Response to Molecular Gradients with a Computational Model of Filopodial Dynamics [PDF]
, 2004 Axons are often guided to their targets in the developing nervous system by attractive or repulsive molecular concentration gradients. We propose a computational model for gradient sensing and directed movement of the growth cone mediated by filopodia ...
Caton A. +3 more
core +3 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Paroxysmal kinesigenic dyskinesia (PKD) is the most common hereditary paroxysmal movement disorder. The PRRT2 gene is the first identified causative gene and accounts for the majority of PKD. In this study, we investigated the pathogenicity of PRRT2 variants in the splice regions. Methods Patients with clinically suspected PKD and no
Jiao‐Jiao Xu +5 more
wiley +1 more source
Vestnik Dermatologii i Venerologii, 2017 Goal. To assess the effect of topical treatment of atopic dermatitis patients with the 0.1% tacrolimus ointment on the itching intensity and skin expression level of growth factor proteins affecting the intensity of cutaneous innervation.
V. V. Chikin +3 more
doaj +1 more source
Enzymatic activities of mouse nerve growth factor and its subunits. [PDF]
, 1968 Lloyd A. Greene +2 more
openalex +1 more source