Results 341 to 350 of about 1,869,384 (384)
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Journal of Biomedical Materials Research. Part A, 2014
Artificial nerve guidance conduits (NGCs) containing bioactive neurotrophic factors and topographical structure to biomimic native tissues are essential for efficient regeneration of nerve gaps.
Kuihua Zhang +3 more
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Artificial nerve guidance conduits (NGCs) containing bioactive neurotrophic factors and topographical structure to biomimic native tissues are essential for efficient regeneration of nerve gaps.
Kuihua Zhang +3 more
semanticscholar +1 more source
Tissue Localization of Nerve Growth Factor and Nerve Growth Factor Receptors
1991The pioneering investigations of Levi-Montalcini and coworkers established that nerve growth factor (NGF) is an important physiological regulator of neurons of the peripheral nervous system. No doubt in part because of the dramatic and specific effects on the sympathetic and sensory nervous system resulting from immunochemically depriving rodents of ...
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The nerve growth factor family
Progress in Growth Factor Research, 1990Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) are small, basic, secretory proteins that allow the survival of specific neuronal populations. In their biologically active form, after cleavage from their biosynthetic precursors, these three neurotrophic proteins, or neurotrophins, show about 50% amino acid ...
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Nerve Growth Factor: Neurotrophin or Cytokine?
International Archives of Allergy and Immunology, 2003Nerve growth factor (NGF) is a neutrophin exerting an important role in the development and functions of the central and peripheral nervous system. However, it has recently been documented that several immune cells – such as mast cells, lymphocytes and eosinophils – produce, store and release NGF.
BONINI, Sergio +4 more
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1980
Nerve growth factor (NGF) is an insulin-like protein, which regulates growth, development and maintenance of sympathetic and embryonic sensory neurons. It is found in varying amounts in the venom of all tested poisonous snakes and in the male mouse submaxillary gland.
Roger Y. Andres, Ralph A. Bradshaw
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Nerve growth factor (NGF) is an insulin-like protein, which regulates growth, development and maintenance of sympathetic and embryonic sensory neurons. It is found in varying amounts in the venom of all tested poisonous snakes and in the male mouse submaxillary gland.
Roger Y. Andres, Ralph A. Bradshaw
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Human nerve growth factor: Lack of immunocrossreactivity with mouse nerve growth factor
Life Sciences, 1980Abstract Human β-nerve growth factor (hNGF) was purified from term human placenta. The biological potency of hNGF in the chick dorsal root ganglion assay did not differ significantly from that of mouse NGF (mNGF). Molecular weight determinations of mNGF and hMGF were also similar.
Delbert A. Fisher +2 more
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New England Journal of Medicine, 2010
Osteoarthritis, a common, painful condition, occurs at a rate of 1% per year and affects the majority of people who are over 55 years of age. In a proof-of-concept, phase 2 study in this issue of the Journal, Lane and colleagues1 report that blocking the activity of nerve growth factor with a neutralizing humanized monoclonal antibody (tanezumab) can ...
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Osteoarthritis, a common, painful condition, occurs at a rate of 1% per year and affects the majority of people who are over 55 years of age. In a proof-of-concept, phase 2 study in this issue of the Journal, Lane and colleagues1 report that blocking the activity of nerve growth factor with a neutralizing humanized monoclonal antibody (tanezumab) can ...
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Receptors for Nerve Growth Factor
1993Publisher Summary This chapter discusses the two receptors for nerve growth factor (NGF)—namely, (1) the low-affinity NGF receptor and (2) the product of the proto-oncogene trk . It also reviews the way they were originally identified and the structural and functional features of the two receptors.
David S. Battleman +2 more
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Biochemistry, 1986
Pheochromocytoma (PC12) cells have been found to differ from dorsal root ganglionic cells with respect to the modulation of the beta nerve growth factor (beta NGF) binding properties elicited by alpha NGF and gamma NGF. In contrast to our previous results with intact dorsal root ganglionic cells in which only high-affinity binding was blocked, alpha ...
Kenneth E. Neet, Nathaniel R. Woodruff
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Pheochromocytoma (PC12) cells have been found to differ from dorsal root ganglionic cells with respect to the modulation of the beta nerve growth factor (beta NGF) binding properties elicited by alpha NGF and gamma NGF. In contrast to our previous results with intact dorsal root ganglionic cells in which only high-affinity binding was blocked, alpha ...
Kenneth E. Neet, Nathaniel R. Woodruff
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1987
Beta-nerve growth factor (s-NGF) is a polypeptide of 118 amino acids, and is a member of the group of polypeptide growth factors (PGF) that includes epidermal growth factor (EGF), platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), and several other growth factors (see Table 1).
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Beta-nerve growth factor (s-NGF) is a polypeptide of 118 amino acids, and is a member of the group of polypeptide growth factors (PGF) that includes epidermal growth factor (EGF), platelet-derived growth factor (PDGF), fibroblast growth factor (FGF), and several other growth factors (see Table 1).
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