Results 31 to 40 of about 1,827,011 (365)

Thick collagen-based 3D matrices including growth factors to induce neurite outgrowth [PDF]

open access: yesActa Biomaterialia 8, 9 (2012) 3302-3312, 2012
Designing synthetic microenvironments for cellular investigations is a very active area of research at the crossroads of cell biology and materials science. The present work describes the design and functionalization of a three-dimensional (3D) culture support dedicated to the study of neurite outgrowth from neural cells.
arxiv   +1 more source

A ‘Relay’-Type Drug-Eluting Nerve Guide Conduit: Computational Fluid Dynamics Modeling of the Drug Eluting Efficiency of Various Drug Release Systems

open access: yesPharmaceutics, 2022
Nerve guidance conduits (NGCs) are tubular scaffolds that act as a bridge between the proximal and distal ends of the native nerve to facilitate the nerve regeneration.
Jiarui Zhou   +1 more
doaj   +1 more source

Can ReGeneraTing Agents Improve Functional Recovery of Transected Peripheral Nerve through a Nerve Gap Bridged with an Artery Graft?

open access: yesJournal of Reconstructive Microsurgery Open, 2019
Background The purpose of this study was to use artery grafts filled with CACIPLIQ20 and see if they promote nerve regeneration. Methods Sixty male Wistar rats were used. The rats were randomly divided into four experimental groups (n = 15):
George Alexopoulos   +10 more
doaj   +1 more source

Analysis of post-traumatic growth status and its influencing factors in patients with facial palsy

open access: yesChinese Neurosurgical Journal, 2018
Background Facial nerve paralysis in patients occurs in varying degrees of self-image disorders, both physically and mentally, resulting in low self-esteem, anxiety, depression, and even suicide; however, there were few researches on psychological ...
Qian Li   +5 more
doaj   +1 more source

Nerve Growth Factor: Early Studies and Recent Clinical Trials

open access: yesCurrent Neuropharmacology, 2018
Since its discovery, nerve growth factor (NGF) has long occupied a critical role in developmental and adult neuro-biology for its many important regulatory functions on the survival, growth and differentiation of nerve cells in the peripheral and central
M. Rocco, M. Soligo, L. Manni, L. Aloe
semanticscholar   +1 more source

Morphofunctional Characterization of Different Tissue Factors in Congenital Diaphragmatic Hernia Affected Tissue

open access: yesDiagnostics, 2021
Congenital diaphragm hernia (CDH) is a congenital disease that occurs during prenatal development. Although the morbidity and mortality rate is rather significant, the pathogenesis of CDH has been studied insignificantly due to the decreased ...
Ricards Kaulins   +3 more
doaj   +1 more source

Nerve Growth Factor and Autoimmune Diseases

open access: yesCurrent Issues in Molecular Biology, 2023
NGF plays a crucial immunomodulatory role and increased levels are found in numerous tissues during autoimmune states. NGF directly modulates innate and adaptive immune responses of B and T cells and causes the release of neuropeptides and neurotransmitters controlling the immune system activation in inflamed tissues.
Sergio Terracina   +10 more
openaire   +5 more sources

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Potential application of let-7a antagomir in injured peripheral nerve regeneration

open access: yesNeural Regeneration Research, 2023
Neurotrophic factors, particularly nerve growth factor, enhance neuronal regeneration. However, the in vivo applications of nerve growth factor are largely limited by its intrinsic disadvantages, such as its short biological half-life, its contribution ...
Qian-Qian Chen   +6 more
doaj   +1 more source

Tumor microenvironment (Part I): Tissue integrity in a rat model of peripheral neural cancer [PDF]

open access: yesHeliyon, Volume 10, Issue 13, e33932, July 15, 2024
ICAM-1 (intercellular adhesion molecule 1) and MPZ (myelin protein zero) are thought to be a factor in the integrity of nerve tissues. In this report, we attempted to trace the expression of ICAM-1, responsible for cell-to-cell adhesion, and of MPZ, the main constituent of myelin sheath, in malignant tissues of the sciatic nerve (SN) in inbred male ...
arxiv   +1 more source

Home - About - Disclaimer - Privacy