Results 11 to 20 of about 12,848,873 (295)

Cavernous nerve reconstruction with autologous vein graft and platelet-derived growth factors

open access: yesAsian Journal of Andrology, 2017
In this study, we investigated the feasibility of using autologous vein graft and platelet-derived growth factors to bridge transected cavernous nerve in a rat model.
Xie-Gang Ding   +4 more
doaj   +2 more sources

Analysis of the C/EBP family of transcription factors in neuronal repair [PDF]

open access: yes, 2009
PhDNeurons within the peripheral nervous system (PNS) have a remarkable ability to repair themselves after injury; however, neurons within the central nervous system (CNS) do not spontaneously regenerate.
López de Heredia, Luis
core   +4 more sources

Expression of neuropeptides – galanin and Reg2 - in subcategories of nociceptors after nerve injury [PDF]

open access: yes, 2010
PhDNeuropeptides show dynamic changes in expression after nerve injury, and have been implicated in chronic pain states. I sought to compare expression of two peptides which are upregulated after nerve injury, galanin and Reg2, and to determine the ...
Burrows, Karen Lynne
core   +4 more sources

An organized 3D in vitro model for peripheral nerve studies [PDF]

open access: yes, 2013
Three-dimensional cell cultures have been proposed to address the limitations in two-dimensional cell cultures (i.e. lack of relevant architectural features) and very few have developed 3D cell culture methods for peripheral nerve studies. Therefore, the
Daud, Muhammad Fauzi
core   +5 more sources

Willin, an upstream component of the Hippo signaling pathway, orchestrates mammalian peripheral nerve fibroblasts [PDF]

open access: yes, 2013
Willin/FRMD6 was first identified in the rat sciatic nerve, which is composed of neurons, Schwann cells, and fibroblasts. Willin is an upstream component of the Hippo signaling pathway, which results in the inactivation of the transcriptional coactivator
Tilston-Lünel, A.M.   +47 more
core   +2 more sources

Role of neurotrophic factors in enhancing linear axonal growth of ganglionic sensory neurons in vitro

open access: yesNeural Regeneration Research, 2020
Neurotrophins play a major role in the regulation of neuronal growth such as neurite sprouting or regeneration in response to nerve injuries. The role of nerve growth factor, neurotrophin-3, and brain-derived neurotrophic factor in maintaining the ...
Michele Fornaro   +6 more
doaj   +1 more source

Morphology and Nanomechanics of Sensory Neurons Growth Cones following Peripheral Nerve Injury [PDF]

open access: yes, 2012
A prior peripheral nerve injury in vivo, promotes a rapid elongated mode of sensory neurons neurite regrowth in vitro. This in vitro model of conditioned axotomy allows analysis of the cellular and molecular mechanisms leading to an improved neurite re ...
Vivien Szabo   +24 more
core   +2 more sources

Increased Brain-Derived Neurotrophic Factor Levels in Cerebrospinal Fluid During the Acute Phase in TBI-Induced Mechanical Allodynia in the Rat Model

open access: yesJournal of Pain Research, 2022
Wangseok Do,1 Jiseok Baik,1,2 Soeun Jeon,1 Chang-Min You,1 Dahyun Kang,1 Young-Hoon Jung,1 Jiyoon Lee,3 Hae-Kyu Kim1,2 1Department of Anesthesia and Pain Medicine and Biomedical Research Institute Pusan National University Hospital, Busan, Republic of ...
Do W   +7 more
doaj  

Neuropathological and Behavioral Consequences of Adeno-Associated Viral Vector-Mediated Continuous Intrastriatal Neurotrophin Delivery in a Focal Ischemia Model in Rats

open access: yesNeurobiology of Disease, 2002
Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) were continuously delivered to the striatum at biologically active levels via recombinant adeno-associated viral (rAAV) gene transfer 4–5 weeks prior to 30 min of middle cerebral ...
Gunnar Andsberg   +5 more
doaj   +1 more source

Polydopamine-modified chitin conduits with sustained release of bioactive peptides enhance peripheral nerve regeneration in rats

open access: yesNeural Regeneration Research, 2022
[INLINE:1] The introduction of neurotrophic factors into injured peripheral nerve sites is beneficial to peripheral nerve regeneration. However, neurotrophic factors are rapidly degraded in vivo and obstruct axonal regeneration when used at a ...
Ci Li   +7 more
doaj   +1 more source

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