Results 21 to 30 of about 480,406 (311)
Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) were continuously delivered to the striatum at biologically active levels via recombinant adeno-associated viral (rAAV) gene transfer 4–5 weeks prior to 30 min of middle cerebral ...
Gunnar Andsberg +5 more
doaj +1 more source
Wound repair is a key step in the treatment of skin injury caused by burn, surgery, and trauma. Various stem cells have been proven to promote wound healing and skin regeneration as candidate seed cells.
Ziying Zhu +8 more
doaj +1 more source
Addition of insulin-like growth factors (IGF-1) for the regeneration of critical defects in peripheral nerve injuries. Biological findings [PDF]
Producción CientíficaThe purpose is analyze the biological and cellular regeneration of non-repairable lesions of peripheral nerve by muscle graft enhanced with growth factors. Methods: Controlled clinical experimental trial, level I evidence.
Barrio Sanz, Patricia +5 more
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Neuropeptídeos na pele Neuropeptides in the skin
Há evidências crescentes de que a inervação cutânea é capaz de modular uma variedade de fenômenos cutâneos agudos e crônicos, interagindo com as células da pele e seus componentes imunes.
Pedro Kalil-Gaspar
doaj +1 more source
KLF9 and JNK3 Interact to Suppress Axon Regeneration in the Adult CNS [PDF]
Neurons in the adult mammalian CNS decrease in intrinsic axon growth capacity during development in concert with changes in Krüppel-like transcription factors (KLFs). KLFs regulate axon growth in CNS neurons including retinal ganglion cells (RGCs). Here,
Apara, Akintomide +16 more
core +2 more sources
神経成長因子(nerve growth factor; NGF)は,知覚神経二ューロン,交感神経ニューロン,中枢の一部のコリン系ニューロンの分化・成熟を促し,生存・機能を維持し,突起伸展を引き起こす,分子量約26000の蛋白質である. NGFは,神経科学,発生学の分野において最も古くから実体の明らかにされていた分子のひとつで, NGFの研究で得られた膨大な知見から神経回路の形成過程や調節機構の概要が窺い知ることができるようになった.最近では, NGFを投与すると,末梢神経の軸索再生が促進されること,遅発性ニューロン死が抑制されること,老化による学習記憶能力低下が抑制されること,などが報告され,臨床応用への期待も高まってきている.
Y, Furukawa, S, Furukawa
openaire +3 more sources
The glia response after peripheral nerve injury: A comparison between Schwann cells and olfactory ensheathing cells and their uses for neural regenerative therapies [PDF]
The peripheral nervous system (PNS) exhibits a much larger capacity for regeneration than the central nervous system (CNS). One reason for this difference is the difference in glial cell types between the two systems.
Barton, Matthew J. +4 more
core +2 more sources
Background: Late Onset Bipolar Disorder (LOBD) is the development of Bipolar Disorder (BD) at an age above 50 years old. It is often difficult to differentiate from other aging dementias, such as Alzheimer's Disease (AD), because they share cognitive and
Ariadna Besga +12 more
doaj +1 more source
Nerve growth factor, brain-derived neurotrophic factor, and the chronobiology of mood: a new insight into the "neurotrophic hypothesis" [PDF]
The light information pathways and their relationship with the body rhythms have generated a new insight into the neurobiology and the neurobehavioral sciences, as well as into the clinical approaches to human diseases associated with disruption of ...
IANNITELLI, ANGELA +2 more
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Angiogenic and Neurotrophic Effects of Human Bone Marrow Mesenchymal Stem Cell-Derived Conditioned Medium for Erectile Dysfunction [PDF]
Department of Biomedical EngineeringA three-dimensional spheroid culture system to harvest conditioned medium (CM) from human bone marrow-derived mesenchymal stem cells (hBM-MSCs) with high efficiency were introduced and investigated the therapeutic ...
Kim, Seul Gi
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