Results 51 to 60 of about 1,821,081 (364)
Physical Stimulation Combined with Biomaterials Promotes Peripheral Nerve Injury Repair
Peripheral nerve injury (PNI) is a clinical problem with high morbidity that can cause severe damage. Surgical suturing or implants are usually required due to the slow speed and numerous factors affecting repair after PNI.
Zhipeng Zeng+5 more
doaj +1 more source
Neuroprotection, Growth Factors and BDNF-TrkB Signalling in Retinal Degeneration
Neurotrophic factors play key roles in the development and survival of neurons. The potent neuroprotective effects of neurotrophic factors, including brain-derived neurotrophic factor (BDNF), ciliary neurotrophic factor (CNTF), glial cell-line derived ...
A. Kimura+4 more
semanticscholar +1 more source
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi+6 more
wiley +1 more source
Roles of neural stem cells in the repair of peripheral nerve injury
Currently, researchers are using neural stem cell transplantation to promote regeneration after peripheral nerve injury, as neural stem cells play an important role in peripheral nerve injury repair.
Chong Wang+4 more
doaj +1 more source
Peripheral nerve injuries often result in lifelong disabilities despite advanced surgical interventions, indicating the urgent clinical need for effective therapies.
Katharina M. Prautsch+5 more
doaj +1 more source
Nerve growth factor (NGF) regulates the microtubule-dependent extension and maintenance of axons by some peripheral neurons. We show here that one effect of NGF is to promote microtubule assembly during neurite outgrowth in PC12 cells.
David+5 more
semanticscholar +1 more source
Genomic landscape and preclinical models of angiosarcoma
Angiosarcomas are a rare and aggressive cancer with a poor prognosis for patients. The genomic landscape of angiosarcoma can be highly complex and heterogenous; however, recent studies have identified some common features especially within anatomic and molecular subgroups.
Annaleigh Benton+3 more
wiley +1 more source
Partial denervation or paralysis of adult skeletal muscle is followed by nerve sprouting, probably due to release of diffusible sprout- inducing activity by inactive muscle.
Pica Caroni, P. Grandes
semanticscholar +1 more source
High‐grade serous ovarian cancer (HGSOC) is the most common and aggressive type of ovarian cancer with urgent need for new treatment strategies. This study evaluates plasma‐activated media (PAM) as a novel treatment for HGSOC, showing its ability to selectively induce oxidative stress and apoptosis in HGSOC cell lines, patient ascites cells and primary
Lorena T. Davies+9 more
wiley +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source