Results 11 to 20 of about 3,082,625 (411)

Mesenchymal stem cell treatment for peripheral nerve injury: a narrative review

open access: yesNeural Regeneration Research, 2021
Peripheral nerve injuries occur as the result of sudden trauma and lead to reduced quality of life. The peripheral nervous system has an inherent capability to regenerate axons.
Rui-Cheng Zhang   +8 more
semanticscholar   +1 more source

Progress in methods for evaluating Schwann cell myelination and axonal growth in peripheral nerve regeneration via scaffolds

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
Peripheral nerve injury (PNI) is a neurological disorder caused by trauma that is frequently induced by accidents, war, and surgical complications, which is of global significance.
Jue Ling   +8 more
doaj   +1 more source

Volumetric MRI is a promising outcome measure of muscle reinnervation

open access: yesScientific Reports, 2021
The development of outcome measures that can track the recovery of reinnervated muscle would benefit the clinical investigation of new therapies which hope to enhance peripheral nerve repair. The primary objective of this study was to assess the validity
Matthew Wilcox   +8 more
doaj   +1 more source

Peripheral nerve injury and myelination: Potential therapeutic strategies

open access: yesJournal of Neuroscience Research, 2020
Traumatic peripheral nerve injury represents a major clinical and public health problem that often leads to significant functional impairment and permanent disability. Despite modern diagnostic procedures and advanced microsurgical techniques, functional
M. Modrak   +4 more
semanticscholar   +1 more source

Characterising cellular and molecular features of human peripheral nerve degeneration

open access: yesActa Neuropathologica Communications, 2020
Nerve regeneration is a key biological process in those recovering from neural trauma. From animal models it is known that the regenerative capacity of the peripheral nervous system (PNS) relies heavily on the remarkable ability of Schwann cells to ...
Matthew B. Wilcox   +6 more
doaj   +1 more source

Pure-silk fibroin hydrogel with stable aligned micropattern toward peripheral nerve regeneration

open access: yesNanotechnology Reviews, 2021
Successful repair of long-distance peripheral nerve injuries remains a challenge in the clinic. Rapid axon growth is a key to accelerate nerve regeneration.
Gu Xinyi   +6 more
doaj   +1 more source

Light-Triggered Adhesive Silk-Based Film for Effective Photodynamic Antibacterial Therapy and Rapid Hemostasis

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Successful control of massive hemorrhage in deep wounds with irregular shape and low elasticity still remains great challenges in the clinic. As the wound sites are usually at risk of bacterial infection, it is necessary to design an ideal hemostatic ...
Tingting Huang   +7 more
doaj   +1 more source

Incidence of Nerve Injury After Extremity Trauma in the United States

open access: yesHAND, 2020
Background Traumatic peripheral nerve injuries cause chronic pain, disability, and long-term reductions in quality of life. However, their incidence after extremity trauma remains poorly understood.
William M. Padovano   +7 more
semanticscholar   +1 more source

Inhibition of Schwann cell pannexin 1 attenuates neuropathic pain through the suppression of inflammatory responses

open access: yesJournal of Neuroinflammation, 2022
Background Neuropathic pain is still a challenge for clinical treatment as a result of the comprehensive pathogenesis. Although emerging evidence demonstrates the pivotal role of glial cells in regulating neuropathic pain, the role of Schwann cells and ...
Qian Wang   +4 more
doaj   +1 more source

Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes [PDF]

open access: yes, 2015
Background: NOD-like receptors (Nlrs) are key regulators of immune responses during infection and autoimmunity. A subset of Nlrs assembles inflammasomes, molecular platforms that are activated in response to endogenous danger and microbial ligands and ...
De Winter, Vicky   +6 more
core   +2 more sources

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