Results 21 to 30 of about 2,724,357 (343)

Regenerative Role of T Cells in Nerve Repair and Functional Recovery

Frontiers in Immunology, 2022
The immune system is essential in the process of nerve repair after injury. Successful modulation of the immune response is regarded as an effective approach to improving treatment outcomes.
Xiaoxuan Tang, Xiaoxuan Tang, Qiaoyuan Li, Tingting Huang, Han Zhang, Xiaoli Chen, Jue Ling, Yumin Yang   +7 more
doaj   +1 more source

Natural-Based Biomaterials for Peripheral Nerve Injury Repair

Frontiers in Bioengineering and Biotechnology, 2020
Peripheral nerve injury treatment is a relevant problem because of nerve lesion high incidence and because of unsatisfactory regeneration after severe injuries, thus resulting in a reduced patient’s life quality.
B. Fornasari, Giacomo Carta, G. Gambarotta, S. Raimondo   +3 more
semanticscholar   +1 more source

Inhibition of Schwann cell pannexin 1 attenuates neuropathic pain through the suppression of inflammatory responses

Journal of Neuroinflammation, 2022
Background Neuropathic pain is still a challenge for clinical treatment as a result of the comprehensive pathogenesis. Although emerging evidence demonstrates the pivotal role of glial cells in regulating neuropathic pain, the role of Schwann cells and ...
Qian Wang, Han-yang Li, Zhuo-min Ling, Gang Chen, Zhong-Ya Wei   +4 more
doaj   +1 more source

Nerve Ultrasound in Traumatic and Iatrogenic Peripheral Nerve Injury

Diagnostics, 2020
Peripheral nerve injury is a potentially debilitating disorder that occurs in an estimated 2–3% of all patients with major trauma, in a similar percentage of medical procedures.
J. Wijntjes, A. Borchert, N. van Alfen
semanticscholar   +1 more source

The Success and Failure of the Schwann Cell Response to Nerve Injury

Frontiers in Cellular Neuroscience, 2019
The remarkable plasticity of Schwann cells allows them to adopt the Remak (non-myelin) and myelin phenotypes, which are specialized to meet the needs of small and large diameter axons, and differ markedly from each other.
K. Jessen, R. Mirsky
semanticscholar   +1 more source

The Effect of Schwann Cells/Schwann Cell-Like Cells on Cell Therapy for Peripheral Neuropathy

Frontiers in Cellular Neuroscience, 2022
Peripheral neuropathy is a common neurological issue that leads to sensory and motor disorders. Over time, the treatment for peripheral neuropathy has primarily focused on medications for specific symptoms and surgical techniques.
Qian Wang, Fang-Yu Chen, Zhuo-Min Ling, Wen-Feng Su, Ya-Yu Zhao, Gang Chen, Gang Chen, Gang Chen, Zhong-Ya Wei   +8 more
doaj   +1 more source

Mechanistic Role of Reactive Oxygen Species and Therapeutic Potential of Antioxidants in Denervation- or Fasting-Induced Skeletal Muscle Atrophy

Frontiers in Physiology, 2018
Skeletal muscle atrophy occurs under various conditions, such as disuse, denervation, fasting, aging, and various diseases. Although the underlying molecular mechanisms are still not fully understood, skeletal muscle atrophy is closely associated with ...
Jiaying Qiu, Qingqing Fang, Tongtong Xu, Changyue Wu, Lai Xu, Lingbin Wang, Xiaoming Yang, Shu Yu, Qi Zhang, Fei Ding, Hualin Sun   +10 more
doaj   +1 more source

Comparative intra- and inter-observer reliability of two methods for evaluating intraoperative ultrasonography-based spinal cord hyperechogenicity intensity in degenerative cervical myelopathy

BMC Musculoskeletal Disorders, 2022
Objectives During French-door laminoplasty, a linear array transducer of IOUS was used to observe and record the spinal cord decompression. To acquire a higher-reliability method, and compare the in-observer and inter-observer reliability of two methods ...
Huachuan Wu, Guoliang Chen, Xianlong Li, Zhengya Zhu, Zuofeng Xu, Xizhe Liu, Shaoyu Liu   +6 more
doaj   +1 more source

Hyaluronic acid ameliorates intervertebral disc degeneration via promoting mitophagy activation

Frontiers in Bioengineering and Biotechnology, 2022
Activation of mitophagy was considered to be a potential therapeutic strategy for intervertebral disc degeneration (IDD). There was evidence suggesting that hyaluronic acid (HA) can protect mitochondria from oxidative stress in chondrocytes, but its ...
Fu Zhang, Fu Zhang, Songjuan Wang, Manman Gao, Baoliang Li, Zhongyuan He, Tao Tang, Zhengya Zhu, Shaoyu Liu, Shaoyu Liu, Zhiyu Zhou, Zhiyu Zhou   +11 more
doaj   +1 more source

Isoquercitrin Delays Denervated Soleus Muscle Atrophy by Inhibiting Oxidative Stress and Inflammation

Frontiers in Physiology, 2020
Although denervated muscle atrophy is common, the underlying molecular mechanism remains unelucidated. We have previously found that oxidative stress and inflammatory response may be early events that trigger denervated muscle atrophy. Isoquercitrin is a
Yuntian Shen, Qiuyu Zhang, Ziwei Huang, Jianwei Zhu, Jiayi Qiu, Wenjing Ma, Xiaoming Yang, Fei Ding, Hualin Sun   +8 more
doaj   +1 more source