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Characterising cellular and molecular features of human peripheral nerve degeneration
Acta Neuropathologica Communications, 2020 Nerve regeneration is a key biological process in those recovering from neural trauma. From animal models it is known that the regenerative capacity of the peripheral nervous system (PNS) relies heavily on the remarkable ability of Schwann cells to ...
Matthew B. Wilcox +6 more
doaj +1 more source
Natural-Based Biomaterials for Peripheral Nerve Injury Repair
Frontiers in Bioengineering and Biotechnology, 2020 Peripheral nerve injury treatment is a relevant problem because of nerve lesion high incidence and because of unsatisfactory regeneration after severe injuries, thus resulting in a reduced patient’s life quality.
B. Fornasari +3 more
semanticscholar +1 more source
Peripheral nerve injuries [PDF]
The American Journal of Surgery, 1932 Nerve injuries caused by medical interventions (Iatrogenic lesions) can complicate procedures and affect any part of the peripheral nervous system. Available data is fragmentary and little information is accessible on the overall incidence of iatrogenic nerve lesions that ranges from 1.5 to 15%.[1, 2] Major drawbacks are the limited number of patients ...
Anesti, Katerina, Caine, Paul
openaire +14 more sources
Journal of Neuroinflammation, 2022 Background Neuropathic pain is still a challenge for clinical treatment as a result of the comprehensive pathogenesis. Although emerging evidence demonstrates the pivotal role of glial cells in regulating neuropathic pain, the role of Schwann cells and ...
Qian Wang +4 more
doaj +1 more source
Nerve Ultrasound in Traumatic and Iatrogenic Peripheral Nerve Injury
Diagnostics, 2020 Peripheral nerve injury is a potentially debilitating disorder that occurs in an estimated 2–3% of all patients with major trauma, in a similar percentage of medical procedures.
J. Wijntjes, A. Borchert, N. van Alfen
semanticscholar +1 more source
BMC Musculoskeletal Disorders, 2022 Objectives During French-door laminoplasty, a linear array transducer of IOUS was used to observe and record the spinal cord decompression. To acquire a higher-reliability method, and compare the in-observer and inter-observer reliability of two methods ...
Huachuan Wu +6 more
doaj +1 more source
The Effect of Schwann Cells/Schwann Cell-Like Cells on Cell Therapy for Peripheral Neuropathy
Frontiers in Cellular Neuroscience, 2022 Peripheral neuropathy is a common neurological issue that leads to sensory and motor disorders. Over time, the treatment for peripheral neuropathy has primarily focused on medications for specific symptoms and surgical techniques.
Qian Wang +8 more
doaj +1 more source
The Success and Failure of the Schwann Cell Response to Nerve Injury
Frontiers in Cellular Neuroscience, 2019 The remarkable plasticity of Schwann cells allows them to adopt the Remak (non-myelin) and myelin phenotypes, which are specialized to meet the needs of small and large diameter axons, and differ markedly from each other.
K. Jessen, R. Mirsky
semanticscholar +1 more source
Frontiers in Physiology, 2018 Skeletal muscle atrophy occurs under various conditions, such as disuse, denervation, fasting, aging, and various diseases. Although the underlying molecular mechanisms are still not fully understood, skeletal muscle atrophy is closely associated with ...
Jiaying Qiu +10 more
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Frontiers in Physiology, 2020 Although denervated muscle atrophy is common, the underlying molecular mechanism remains unelucidated. We have previously found that oxidative stress and inflammatory response may be early events that trigger denervated muscle atrophy. Isoquercitrin is a
Yuntian Shen +8 more
doaj +1 more source