Results 81 to 90 of about 829,895 (308)

Advances in adhesion interfaces of peripheral nerve repair materials: mechanism, classification, evaluation method, and functionalization

Frontiers in Cell and Developmental Biology
Peripheral nerve injury is a prevalent clinical disease, but achieving functional recovery remains a significant research challenge. In recent years, the therapeutic efficacy of nerve repair materials has garnered widespread attention from researchers ...
Qi Meng, Qi Meng, Qi Meng, Qi Meng, Meng Zhang, Meng Zhang, Meng Zhang, Meng Zhang, Yichong Zhang, Yichong Zhang, Yichong Zhang, Yichong Zhang, Haoran Jiang, Haoran Jiang, Haoran Jiang, Haoran Jiang, Yang Qu, Yang Qu, Yang Qu, Yang Qu, Ci Li, Chenyujun Hu, Chenyujun Hu, Chenyujun Hu, Chenyujun Hu, Zhihao Lin, Zhihao Lin, Zhihao Lin, Zhihao Lin, Bohan Xing, Bohan Xing, Bohan Xing, Bohan Xing, Fengxue Zhu, Peixun Zhang, Peixun Zhang, Peixun Zhang, Peixun Zhang, Peixun Zhang   +38 more
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

A small molecule screen identifies in vivo modulators of peripheral nerve regeneration in zebrafish. [PDF]

PLoS ONE, 2017
Adult vertebrates have retained the ability to regenerate peripheral nerves after injury, although regeneration is frequently incomplete, often leading to functional impairments.
Juliane Bremer, Julianne Skinner, Michael Granato   +2 more
doaj   +1 more source

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini, Giulia Tammam, Andra Ezaru, Manuela Gambella, Benoît Sanson, Luisa Villa, Michele Cavalli, Mihai‐Bogdan Ioncea, Angela Puma, Sabrina Sacconi   +9 more
wiley   +1 more source

The role of growth associated transcription factors c-Jun and ATMIN in neuronal regeneration and repair [PDF]

, 2010
Subsequent to neuronal injury, increased levels of protein synthesis accompany associated rises in transcription factor expression. Two transcription factors involved in the cellular stress response are c-Jun and ATMIN. Neuron-specific deletion of c-Jun
Ruff, C.A.D.B.
core  

Efficacy of Fampridine on Refractory Optic Neuritis in Neuromyelitis Optica Spectrum Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorders (NMOSD) usually occur with acute refractory optic neuritis (ON). However, there is a lack of efficacious treatments to improve recovery. Since fampridine has been found to improve the prognosis of multiple sclerosis (MS) and MS‐related ON, it is necessary to explore the efficacy of fampridine ...
Hongxuan Wang, Wanru Chen, Xiangpen Li, Hengjian Lu, Chenguang Li, Xiaoni Zhang, Lulu Bu, Xiaoyu Xu, Qingyu Shen, Ying Peng   +9 more
wiley   +1 more source

TrkB dependent adult hippocampal progenitor differentiation mediates sustained ketamine antidepressant response

Nature Communications, 2017
The precise mechanism for the sustained antidepressant action of ketamine is unclear. This study shows ketamine can promote neuronal differentiation via TrkB-ERK activation in mice and the sustained behavioral effect is attenuated when adult neurogenesis
Zhenzhong Ma, Tong Zang, Shari G. Birnbaum, Zilai Wang, Jane E. Johnson, Chun-Li Zhang, Luis F. Parada   +6 more
doaj   +1 more source

An Explicit Constitutive Reconstruction Framework for Mechanical Characterization of Miniaturized 3D‐Printed Specimens

Advanced Engineering Materials, EarlyView.
An explicit constitutive reconstruction framework enables accurate tensile characterization of miniaturized additively manufactured specimens using only the grip‐to‐grip displacement measurements. Progressive validation through self‐consistency, analytical comparison, and inverse finite element method (iFEM) benchmarking demonstrates constitutive ...
Junqing Leng, Caralyn Collins, Pengpeng Zhang, Joanna Zhang, Cheng Sun   +4 more
wiley   +1 more source

Regeneration of nerves [PDF]

Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character, 1906
Abstract In 1901 two of us published a paper on Nerve Degeneration, a subject which it is almost impossible to study without taking into account the closely-related subject of nerve regeneration. From the microscopic study of the distal portions of divided nerve trunks we arrived at the conclusion that the activity of the neurilemmal ...
Frederick Walker Mott, William Dobinson Halliburton, Arthur Edmunds   +2 more
openaire   +1 more source

Morphology, Transport, and Dynamics of Protein Adsorption in Open‐Cell Metal Foam

Advanced Engineering Materials, EarlyView.
Stainless steel (SS) open‐cell foams are shown to adsorb more protein per unit area than previously reported 316L SS and chromium oxide surfaces under static and flow conditions. An integrated approach combining 3D pore imaging, flow simulation, and protein adsorption experiments characterizes the foam’s performance.
Chinmaya Prerana Inguva, Joseph Lavoie, Afsaneh Rabiei   +2 more
wiley   +1 more source